Clindamycin 2,4-diphosphate
Clindamycin 2,4-diphosphate is a related impurity of Clindamycin phosphate (HY-B1064), a prodrug of Clindamycin (HY-B1455). Clindamycin phosphate inhibits protein synthesis by targeting the bacterial ribosomal 50S subunit.
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- CAS. Nr.: 1309048-48-3
- Formel: C18H35ClN2O11P2S
- Molecular Weight:584.94
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
After entering the body, Clindamycin phosphate is rapidly converted into its active form, clindamycin, which effectively inhibits anaerobic bacteria (such as Bacteroides fragilis) and Gram-positive bacteria (such as Staphylococcus aureus and Streptococcus species), but has weaker effects against most Gram-negative bacteria[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1309048-48-3
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Molecular Weight 584.94
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Formel C18H35ClN2O11P2S
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SMILES
O=C([C@@H]1C[C@H](CN1C)CCC)N[C@@H]([C@]2([H])[C@@H]([C@@H]([C@H]([C@H](O2)SC)OP(O)(O)=O)O)OP(O)(O)=O)[C@@H](Cl)C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Li Y, et al. [Isolation and identification of impurities from raw material of clindamycin phosphate]. Yao Xue Xue Bao. 2010 Nov;45(11):1415-20. Chinese. [Content Brief]
[2]. Li H, et al. Clindamycin hydrochloride and clindamycin phosphate: two drugs or one? A retrospective analysis of a spontaneous reporting system. Eur J Clin Pharmacol. 2017 Feb;73(2):251-253. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)