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  4. Alendronate prodrug-1

Alendronate prodrug-1(compound 2) is an inhibitor of farnesyl diphosphate synthase (FPPS). Alendronate prodrug-1 has an antiproliferative effect with an IC50 value of 34.0 μM.

For research use only. We do not sell to patients.

Alendronate prodrug-1 Chemical Structure

Alendronate prodrug-1 Chemical Structure

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Alendronate prodrug-1 Related Antibodies

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Description

Alendronate prodrug-1(compound 2) is an inhibitor of farnesyl diphosphate synthase (FPPS). Alendronate prodrug-1 has an antiproliferative effect with an IC50 value of 34.0 μM[1].

In Vitro

Alendronate prodrug-1 has an antiproliferative effect after light illumination (365 nm, 4 mW/cm2, 10 min) with an IC50 value of 34.0 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Alendronate prodrug-1 Related Antibodies

Cell Proliferation Assay[1]

Cell Line: MDA-MB-231
Concentration: 1-1000 μM
Incubation Time: 72 h
Result: Had a negligible effect on the viability of cancer cells at the highest tested concentration of 400 μM.
Inhibited cell proliferative with an IC50 value of 34.0 μM after exposure to UV light( 365nm，4mW/cm 2, 10 min).
Molecular Weight

639.44

Formula

C22H31N3O15P2
SMILES

COC1=C(OC)C=C(COP(C(CCCN)(O)P(OCC2=CC(OC)=C(OC)C=C2[N+]([O-])=O)(O)=O)(O)=O)C([N+]([O-])=O)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Alendronate prodrug-1 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Alendronate prodrug-1Alendronate prodrug1Alendronate prodrug 1OthersAlendronate prodrugFPPS inhibitorantiproliferativelight activatedInhibitorinhibitorinhibit

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