Alendronate prodrug-1
Alendronate prodrug-1(compound 2) is an inhibitor of farnesyl diphosphate synthase (FPPS). Alendronate prodrug-1 has an antiproliferative effect with an IC50 value of 34.0 μM.
For research use only. We do not sell to patients.
- Formula: C22H31N3O15P2
- Molecular Weight:639.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Alendronate prodrug-1 has an antiproliferative effect after light illumination (365 nm, 4 mW/cm2, 10 min) with an IC50 value of 34.0 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:MDA-MB-231
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Concentration:1-1000 μM
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Incubation Time:72 h
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Result:Had a negligible effect on the viability of cancer cells at the highest tested concentration of 400 μM.
Inhibited cell proliferative with an IC50 value of 34.0 μM after exposure to UV light( 365nm,4mW/cm 2, 10 min).
Chemical Information
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Molecular Weight 639.44
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Formula C22H31N3O15P2
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SMILES
COC1=C(OC)C=C(COP(C(CCCN)(O)P(OCC2=CC(OC)=C(OC)C=C2[N+]([O-])=O)(O)=O)(O)=O)C([N+]([O-])=O)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)