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Results for "

low+toxicity

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (3) Acetolactate Synthase (ALS) (1) Adrenergic Receptor (2) Akt (4) Aldehyde Dehydrogenase (ALDH) (1) Aldose Reductase (2) AMPK (1) Amyloid-β (3) Anaplastic lymphoma kinase (ALK) (1) Androgen Receptor (1) Antibiotic (9) Apoptosis (55) Autophagy (4) Bacterial (28) Bcl-2 Family (5) BCRP (1) Biochemical Assay Reagents (33) Btk (1) c-Kit (4) c-Myc (1) Carbonic Anhydrase (2) Caspase (11) CDK (7) Checkpoint Kinase (Chk) (2) Chloride Channel (1) Choline Kinase (2) Cholinesterase (ChE) (5) COX (3) CRM1 (1) CX3CR1 (1) Cytochrome P450 (3) Dengue Virus (1) Deubiquitinase (1) Dihydrofolate reductase (DHFR) (2) DNA/RNA Synthesis (7) Dopamine Receptor (1) Dopamine Transporter (1) Drug Derivative (6) Drug Intermediate (6) Drug Metabolite (3) EGFR (11) Endogenous Metabolite (13) Enterovirus (2) Environmental Pollutants (16) FAK (2) Ferroptosis (2) FGFR (6) Flavivirus (1) FLT3 (1) Fluorescent Dye (29) Fungal (5) GABA Receptor (2) Gli (1) Glutathione Peroxidase (2) Glyoxalase (GLO) (1) HBV (2) HDAC (5) Hedgehog (1) Herbicide (4) HIF/HIF Prolyl-Hydroxylase (1) Histamine Receptor (5) Histone Demethylase (1) Histone Methyltransferase (1) HIV (2) HSP (3) HSV (9) IAP (3) IFNAR (1) iGluR (1) IKZF Family (1) Indoleamine 2,3-Dioxygenase (IDO) (2) Influenza Virus (1) Insecticide (4) Integrin (1) Interleukin Related (8) IRAK (1) Isotope-Labeled Compounds (17) JAK (3) Liposome (3) mAChR (1) MDM-2/p53 (3) Microtubule/Tubulin (4) Mitochondrial Metabolism (2) MMP (2) Molecular Glues (1) Monoamine Oxidase (1) Monoamine Transporter (1) mTOR (1) Mucin (1) MyD88 (1) NF-κB (7) NO Synthase (3) Nuclear Hormone Receptor 4A/NR4A (1) Orthopoxvirus (2) P-glycoprotein (9) p38 MAPK (1) Parasite (9) PARP (4) PD-1/PD-L1 (3) PDGFR (6) Phospholipase (1) PI3K (4) Potassium Channel (1) PPAR (1) Prostaglandin Receptor (1) PROTACs (5) Pyruvate Kinase (2) Ras (3) Reactive Oxygen Species (ROS) (8) Reference Standards (28) Reverse Transcriptase (2) SARS-CoV (2) Scavenger Receptor Class B type I (SR-BI） (1) Ser/Thr Protease (1) Serotonin Transporter (1) Smo (1) SOD (1) SphK (1) Src (4) STAT (2) STING (1) TET Protein (1) Thyroid Hormone Receptor (1) TNF Receptor (4) Toll-like Receptor (TLR) (5) Topoisomerase (1) Transferrin Receptor (1) Transmembrane Glycoprotein (1) Tyrosinase (1) Urea Transporter (1) VD/VDR (2) VEGFR (2) Virus Protease (1) VZV (1) Wee1 (1) Wnt (2) β-catenin (1)
By Research Areas:	Cancer (131) Cardiovascular Disease (8) Endocrinology (4) Infection (65) Inflammation/Immunology (31) Metabolic Disease (29) Neurological Disease (24)
Click Chemistry:	DBCO (1) Azide (2) Alkynes (8)
Oligonucleotides:	Pegylated Lipids (2) Aptamers (1) Nucleoside Analogs (1) Thymidine (1) Cationic Lipids (1) Polymers (1)

312

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

MCE Kits

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0711

Indocyanine green 40+ Cited Publications Foxgreen; IC Green; Cardiogreen	Fluorescent Dye	Cancer
Indocyanine green (Foxgreen) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography (Ex/Em = 785/813 nm) .

HY-B0525A

Carbenicillin disodium 5+ Cited Publications Sodium carbenicillin	Antibiotic Bacterial	Infection
Carbenicillin disodium (Sodium carbenicillin) is a broad-spectrum semi-synthetic penicillin antibiotic for gram-negative bacteria. Carbenicillin disodium can interfere the cell wall synthesis while displaying low toxicity to plant tissue .

HY-D0227

THAM 1 Publications Verification Tris; Tris(hydroxymethyl)aminomethane	Biochemical Assay Reagents	Metabolic Disease
THAM (Tris) is a low-toxicity amino alcohol buffer, a specific CO₂-consuming proton acceptor that buffers carbon dioxide and acid both in vitro and in vivo. THAM binds protons to form bicarbonate, reduces PaCO₂, and induces intracellular alkalization, thereby ameliorating hypercapnia-induced elevation of pulmonary blood vessels and pulmonary arterial pressure. THAM may cause PaCO₂ rebound, hypoglycemia, and respiratory depression. THAM removes amniotic epithelium and preserves the basement membrane, but depletes extracellular matrix and reduces the adhesion rate of limbal epithelial cells. THAM can act as a CO₂ carrier to enhance the productivity and carbon utilization rate of Scenedesmus obliquus. THAM is a key component of buffer solutions used in various biological, cell culture, biochemical, and molecular biology applications .

HY-D0227A

THAM hydrochloride 1 Publications Verification Tris HCl; Tris(hydroxymethyl)aminomethane hydrochloride	Biochemical Assay Reagents	Metabolic Disease Cancer
THAM hydrochloride (Tris HCl) is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. THAM hydrochloride is an effective amine compound for pH control in the physiological range .

HY-117288

S55746 1 Publications Verification BCL201	Bcl-2 Family	Cancer
S55746 (BCL201) is a potent, orally active and selective BCL-2 inhibitor, with a K_i of 1.3 nM and a K_d of 3.9 nM. S55746 (BCL201) has antitumor activity with low toxicity .

HY-D1583

Cyanine5 DBCO hexafluorophosphate 4 Publications Verification DBCO-Cy5 hexafluorophosphate; Cyanine5 dibenzocyclooctyne hexafluorophosphate	Fluorescent Dye	Others
Cyanine5 DBCO (DBCO-Cy5) hexafluorophosphate is a low-toxicity azide reactive probe (NIR fluorescent dye), for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO hexafluorophosphate has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO hexafluorophosphate can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .

HY-W017522

Adipic acid Hexanedioic acid	Environmental Pollutants Endogenous Metabolite HSV	Infection Metabolic Disease
Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc .

HY-P5307

Peptide A5K INF7-A5K-TAT	Biochemical Assay Reagents	Others
Peptide A5K (INF7-A5K-TAT) is an amphiphilic peptide derived from the HA2-TAT fusion scaffold. Peptide A5K can non-covalently bind to CRISPR ribonucleoproteins and efficiently deliver them to cells, such as primary human T cells, B cells, and NK cells. Peptide A5K enables low-toxicity, precise, and multiplex genome editing, holding great application potential in the field of cell therapy .

HY-D1163

Chromium(III) acetate 2 Publications Verification Chromium acetate; Chromic acetate; Chromium triacetate	Environmental Pollutants AMPK	Metabolic Disease
Chromium(III) acetate (Chromic acetate) is an AMPK inhibitor that promotes lipogenesis by inhibiting AMPK phosphorylation. Chromium(III) acetate has low toxicity in mammals, with an LD₅₀ of 2365 mg/kg in rats .

HY-116387

WR99210 4 Publications Verification BRL 6231 free base	Dihydrofolate reductase (DHFR) Parasite	Infection
WR99210 is an orally active and low-toxicity dihydrofolate reductase (DHFR) inhibitor (IC₅₀<0.075 nM). WR99210 shows good antiparasitic activity and is effective against P. falciparum and P. falciparum strains (including Pyrimethamine< (HY-18062)-resistant P. falciparum strains) as well as T. gondii .

HY-B1950

Quizalofop-p-ethyl (R)-Quizalofop ethyl; Quinofop-ethyl	Environmental Pollutants SOD Herbicide	Infection
Quizalofop-P-ethyl is a low-toxicity herbicide, a highly selective new type of post-emergence herbicide for dryland crops, with high selectivity between gramineous weeds and dicotyledonous crops, and it has good control efficacy against gramineous weeds in broadleaf crop fields.

HY-120635

BMS-1001 hydrochloride	PD-1/PD-L1	Inflammation/Immunology Cancer
BMS-1001 is an orally active human PD-L1/PD-1 immune checkpoint inhibitor. BMS-1001 exhibits low-toxicity in cells. The IC₅₀ value of BMS-1001 in a homogeneous time-resolved fluorescence (HTRF) binding assay is 2.25 nM .

HY-B1217

Bronopol BNPD; BNPK	Environmental Pollutants Bacterial	Infection
Bronopol is an antibacterial agent with low toxicity (to mammals) and high activity (especially against Gram-negative bacteria). Bronopol oxidizes protein thiols, inhibits enzymatic activity, and exhibits antibacterial activity. Bronopol is also a formaldehyde releaser .

HY-W133920

Polypropylene glycol 2000 PPG 2000	Environmental Pollutants Biochemical Assay Reagents	Others
Polypropylene glycol 2000 (PPG 2000) is a polyether produced by ring-opening polymerization of propylene oxide. Polypropylene glycol 2000 has low toxicity, and acts as a dispersant for leather finishing materials, as well as a surfactant and wetting agent for pharmaceutical preparations .

HY-W013762

Tributyl citrate	Environmental Pollutants Biochemical Assay Reagents	Others
Tributyl citrate is a low-toxicity and orally active citrate ester with no genotoxicity or skin sensitizing activity. Tributyl citrate also acts as a plasticizer, solvent, FDA-approved indirect food additive, and topical anesthetic, among other uses. Tributyl citrate induces a needle-prick insensitivity response that lasts for more than 2 hours, and a 5% suspension of it temporarily eliminates the corneal reflex in rabbits. Tributyl citrate causes no significant systemic toxicity in rats and cats at most tested doses, and only may cause growth retardation and gastrointestinal reactions such as diarrhea and nausea at high doses or with repeated oral administration .

HY-142122

Imipramine N-oxide	Drug Metabolite	Neurological Disease
Imipramine N-oxide is the metabolite of Imipramine. Imipramine N-oxide exhibits low toxicity in rat and mouse experiments. Imipramine N-oxide can be used for the research of endogenous depressions .

HY-W393372

THAM maleate 1 Publications Verification Tris maleate; Tris(hydroxymethyl)aminomethane maleate	Environmental Pollutants Biochemical Assay Reagents	Cardiovascular Disease Metabolic Disease
THAM (Tris) maleate is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. THAM maleate is an effective amine compound for pH control in the physiological range .

HY-B0525

Carbenicillin	Antibiotic Bacterial	Infection
Carbenicillin is a broad-spectrum semi-synthetic penicillin antibiotic for gram-negative bacteria. Carbenicillin can interfere the cell wall synthesis while displaying low toxicity to plant tissue .

HY-D0227J

THAM hydrochloride (≥99%, for cell culture) 1 Publications Verification Tris HCl (≥99%, for cell culture); Tris hydrochloride (≥99%, for cell culture)	Biochemical Assay Reagents	Metabolic Disease
THAM hydrochloride (≥99%, for cell culture) is a low-toxicity amino alcohol buffer, a specific CO₂-consuming proton acceptor that buffers carbon dioxide and acid both in vitro and in vivo. THAM hydrochloride (≥99%, for cell culture) binds protons to form bicarbonate, reduces PaCO₂, and induces intracellular alkalization, thereby ameliorating hypercapnia-induced elevation of pulmonary blood vessels and pulmonary arterial pressure. THAM hydrochloride (≥99%, for cell culture) may cause PaCO₂ rebound, hypoglycemia, and respiratory depression. THAM hydrochloride (≥99%, for cell culture) removes amniotic epithelium and preserves the basement membrane, but depletes extracellular matrix and reduces the adhesion rate of limbal epithelial cells. THAM hydrochloride (≥99%, for cell culture) can act as a CO₂ carrier to enhance the productivity and carbon utilization rate of Scenedesmus obliquus. THAM hydrochloride (≥99%, for cell culture) is a key component of buffer solutions used in various biological, cell culture, biochemical, and molecular biology applications .

HY-N10508

Calcitroic acid	Drug Metabolite VD/VDR	Metabolic Disease Cancer
Calcitroic acid is a vitamin D receptor (VDR) agonist that can activate VDR-mediated transcription. Calcitroic acid is the main metabolite of 1,25-dihydroxyvitamin D3, with the highest concentrations found in the liver and mucosa of mice, and it has metabolic stability and very low toxicity .

HY-151483

TK-129	Wnt Histone Demethylase	Cardiovascular Disease
TK-129 is an orally active, low-toxicity, potent KDM5B inhibitor (with high affinity; IC₅₀=44 nM). TK-129 exerts cardioprotective effects by inhibiting KDM5B and blocking the KDM5B-associated Wnt pathway. TK-129 reduces ang II-induced activation of cardiac fibroblasts in vitro and reduces isoprenaline-induced myocardial remodelling and fibrosis in vivo. TK-129 can be used in studies of cardiovascular disease .

HY-B0755

Etimicin sulfate	Antibiotic	Infection
Etimicin (sulfate), a fourth-generation aminoglycoside antibiotic, is now widely clinically used due to its high efficacy and low toxicity.

HY-79504

Ferrocene	Environmental Pollutants Parasite	Infection Cancer
Ferrocene is an important structural core in bioorganometallic chemistry because of its inherent stability, excellent redox properties, and low toxicity. Ferrocene has antimalarial and anticancer properties .

HY-156048

Trifluoromethyl-tubercidin 2 Publications Verification TFMT	Influenza Virus	Infection
Trifluoromethyl-tubercidin (TFMT) is an inhibitor of 2'-O-ribose methyltransferase 1 (MTr1). Trifluoromethyl-tubercidin can inhibit the replication of influenza A and B viruses by interfering with the cap-snatching process of the influenza virus. Trifluoromethyl-tubercidin has antiviral activity and low toxicity .

HY-116387A

WR99210 hydrochloride 4 Publications Verification BRL 6231	Dihydrofolate reductase (DHFR) Parasite	Infection
WR99210 hydrochloride is an orally active and low-toxicity dihydrofolate reductase (DHFR) inhibitor (IC₅₀<0.075 nM). WR99210 hydrochloride shows good antiparasitic activity and is effective against P. falciparum and P. falciparum strains as well as T. gondii .

HY-111817

ACT-451840	Parasite	Infection
ACT-451840 is an orally active, potent and low-toxicity compound, showing activity against sensitive and resistant plasmodium falciparum strains. ACT-451840 targets all asexual blood stages of the parasite, has a rapid onset of action. ACT-451840 behaves in a way similar to artemisinin derivatives, with very rapid onset of action and elimination of parasite. ACT-451840 can be used for the research of malarial .

HY-D2188

IMP-2373	Deubiquitinase	Cancer
IMP-2373 is a low-toxicity activity-based probe targeting covalent pan-deubiquitinase (DUB), which modulates and monitors DUB activity via covalent binding to the catalytic cysteine and active site of DUB. IMP-2373 enables real-time tracking of dynamic intracellular DUB activity in physiologically relevant living cell systems, and quantitative analysis of activity changes induced by pharmacological inhibition or MYC dysregulation. IMP-2373 can be used for research on related diseases such as B-cell lymphoma .

HY-W018584

2-Phenoxyphenol o-Phenoxyphenol	Drug Derivative	Others
2-Phenoxyphenol (o-Phenoxyphenol) is the main product in the photocatalytic reduction and dechlorination reaction of Triclosan (HY-B1119). 2-Phenoxyphenol has low toxicity and can be recycled and utilized as a chemical raw material .

HY-N5058

Dehydroeffusol	Apoptosis	Cancer
Dehydroeffusol is a phenanthrene from medicinal herb Juncus effuses. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. It shows very low toxicity .

HY-D2907

Cyanine 5 DBCO DBCO-Cy5; Cyanine5 dibenzocyclooctyne	Fluorescent Dye	Others
Cyanine5 DBCO (DBCO-Cy5) is a low-toxicity azide reactive probe (NIR fluorescent dye), for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .

HY-Y0383

Dimethyl terephthalate	Biochemical Assay Reagents	Others
Dimethyl terephthalate is a low toxicity, low volatility industrial chemical widely used in the production of polyester fibers and films .

HY-D0227B

THAM acetate 1 Publications Verification Tris acetate; Tris(hydroxymethyl)aminomethane acetate	Biochemical Assay Reagents	Metabolic Disease
THAM acetate is a low-toxicity amino alcohol buffer, a CO₂-consuming proton acceptor that buffers carbon dioxide and acid both in vitro and in vivo. THAM acetate binds protons to form bicarbonate, reduces PaCO₂, and induces intracellular alkalization, thereby ameliorating hypercapnia-induced elevation of pulmonary blood vessels and pulmonary arterial pressure. THAM acetate may cause PaCO₂ rebound, hypoglycemia, and respiratory depression. THAM acetate removes amniotic epithelium and preserves the basement membrane, but depletes extracellular matrix and reduces the adhesion rate of limbal epithelial cells. THAM acetate can act as a CO₂ carrier to enhance the productivity and carbon utilization rate of Scenedesmus obliquus. THAM acetate is a key component of buffer solutions used in various biological, cell culture, biochemical, and molecular biology applications .

HY-118992

Aurodox X 5108; Goldinomycin	Antibiotic Bacterial	Infection
Aurodox (X 5108) is an antibiotic obtained from a streptomyces variant, Aurodox can against a number of gram-positive bacteria. Aurodox shows a very *low toxicity* in mice and promoted poultry growth .

HY-152081

DENV-IN-7	Flavivirus Dengue Virus HIV DNA/RNA Synthesis	Infection
DENV-IN-7, a flavone analog, is a dengue virus (DENV) inhibitor with an EC₅₀ value of 70 nM. DENV-IN-7 has low toxicity against normal cell and anti-dengue activity .

HY-117288A

S55746 hydrochloride 1 Publications Verification BCL201 hydrochloride	Bcl-2 Family	Cancer
S55746 hydrochloride (BCL201 hydrochloride) is a potent, orally active and selective BCL-2 inhibitor, with a K_i of 1.3 nM and a K_d of 3.9 nM. S55746 hydrochloride (BCL201 hydrochloride) has antitumor activity with low toxicity .

HY-147648

Glyoxalase I inhibitor 6 1 Publications Verification	Glyoxalase (GLO)	Cancer
Glyoxalase I inhibitor 6 (Compound 9j) is a glyoxalase I (Glo-I) inhibitor with an IC₅₀ of 1.13 μM. Glyoxalase I inhibitor 6 can be used as anticancer agent with low toxicity .

HY-132297A

PARP1-IN-5 dihydrochloride 1 Publications Verification	PARP	Cancer
PARP1-IN-5 dihydrochloride is a low toxicity, orally active, potent and selective PARP-1 inhibitor (IC₅₀ =14.7 nM). PARP1-IN-5 dihydrochloride can be used for the research of cancer .

HY-W704973

F-ara-EdU	DNA/RNA Synthesis	Cancer
F-ara-EdU is a low-toxic, highly stable probe for DNA synthesis that is used as a marker for cell proliferation and DNA replication by binding to DNA or RNA in cells. F-ara-EdU can also be used to detect the rate of DNA synthesis within cells, as well as to study the mechanisms of DNA repair and damage .

HY-120647

BMS-1001	PD-1/PD-L1	Inflammation/Immunology Cancer
BMS-1001 is an orally active human PD-L1/PD-1 immune checkpoint inhibitor. BMS-1001 exhibits low-toxicity in cells. The IC₅₀ value of BMS-1001 in a homogeneous time-resolved fluorescence (HTRF) binding assay is 2.25 nM .

HY-118165

Phenthoate 2 Publications Verification	Environmental Pollutants Cholinesterase (ChE)	Neurological Disease
Phenthoate is an organophosphorus pesticide having low toxicity in animals. Phenthoate is also a AChE inhibitor .

HY-126199

Tetrachlorvinphos	Endogenous Metabolite	Others
Tetrachlorvinphos is an organophosphorus pesticide that has the activity of inhibiting cholinesterase. Tetrachlorvinphos is used as a pesticide, mainly for the control of pests. Tetrachlorvinphos has low toxicity to mammals .

HY-N7262

Hydroxyvalerenic acid	Others	Cancer
Hydroxyvalerenic acid is isolated from Verbena officinalis, has a low toxicity with IC₅₀ values of 123 and 165 μM against GLC4 and COLO 320 cells, respectively .

HY-140656F

Biotin-PEG20000-Biotin	Fluorescent Dye	Others
Biotin-PEG20000-Biotin is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity.

HY-DY1027

Indocyanine green (solution)	Fluorescent Dye	Cancer
Indocyanine green (Foxgreen) (solution) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography (Ex/Em = 785/813 nm) . Solvent and concentration: DMSO: 10 mM

HY-P3912A

Endotoxin inhibitor TFA	Interleukin Related	Infection
Endotoxin inhibitor TFA is a synthetic peptide that binds lipid A with high affinity, thereby detoxifying LPS (HY-D1056) and preventing LPS-induced cytokine release in vivo. Endotoxin inhibitor TFA inhibits the febrile response to LPS with very low toxicity and lethality .

HY-135739

Benzobarbital	Cytochrome P450	Cardiovascular Disease Metabolic Disease
Benzobarbital is an active low-toxicity inductor of the liver monooxygenase system. Benzobarbital raises cytochrome P-450 concentration. Benzobarbital can be used in the research of post-ischemic liver disease .

HY-106993

Cipralisant GT-2331	Histamine Receptor	Neurological Disease Endocrinology
Cipralisant (GT-2331) is an orally active, low-toxicity, potent, selective, high affinity histamine H3 receptor full antagonist in vivo, and an agonist in vitro, with a pK_i of 9.9 for histamine H3 receptor and a K_i of 0.47 nM for rat histamine H3 receptor. Cipralisant has the potential for attention-deficit hyperactivity disorder research . Cipralisant is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-P5307A

Peptide A5K acetate INF7-A5K-TAT acetate	Biochemical Assay Reagents	Others
Peptide A5K (INF7-A5K-TAT) acetate is an amphiphilic peptide derived from the HA2-TAT fusion scaffold. Peptide A5K acetate can non-covalently bind to CRISPR ribonucleoproteins and efficiently deliver them to cells, such as primary human T cells, B cells, and NK cells. Peptide A5K acetate enables low-toxicity, precise, and multiplex genome editing, holding great application potential in the field of cell therapy .

HY-100334

Pirinixil BR-931	Drug Derivative	Metabolic Disease
Pirinixil is a hypolipidemic agent of low toxicity.

HY-DY1068

Cyanine5 DBCO hexafluorophosphate (solution)	Fluorescent Dye	Others
Cyanine5 DBCO (DBCO-Cy5) hexafluorophosphate (solution) is a low-toxicity azide reactive probe (NIR fluorescent dye) , for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO hexafluorophosphate has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO hexafluorophosphate can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) . Solvent and concentration: DMSO: 10 mM

Cat. No.	Product Name

HY-L219

Antimicrobial Peptides Library

58 compounds

Antimicrobial Peptides (AMPs), also known as antimicrobial peptides or antibiotic peptides, are a class of polypeptides encoded by specific genes in various biological cells and induced by external stimuli. They exhibit broad-spectrum bioactivity against bacteria, fungi, viruses, protozoa, and even tumor cells. AMPs serve as crucial effector molecules in the host's innate immune system.Due to their wide antimicrobial spectrum, low toxicity to normal cells of higher animals, high safety profile, low tendency to induce resistance, and additional benefits such as immune enhancement and antioxidant effects, antimicrobial peptides hold significant promise in new drug development.

MCE offers 58 types of antimicrobial peptides, which can be applied in high-throughput screening for research in anti-infection therapies, immunotherapy, anticancer drug development, and agricultural disease control.

HY-L110

Cyclic Peptide Library

97 compounds

Cyclic peptides are polypeptide chains taking cyclic ring structure, which exhibit diverse biological activities, such as antibacterial activity, immunosuppressive activity and anti-tumor activity. Cyclic peptides, with the features of good binding affinity, target selectivity and low toxicity, show great success as therapeutics. Multiple cyclic peptides are currently in clinical use, for examples, gramicidin and tyrocidine with bactericidal activity, cyclosporin A with immunosuppressive activity, and vancomycin with antibacterial activity. Furthermore, cyclic peptides usually have the sufficient size and a balanced conformational flexibility/rigidity for binding to flat protein-protein interaction (PPI) interfaces, which have potential to develop PPI drugs.

MCE offers a unique collection of 97 cyclic peptides, all of which have good bioactivities. MCE Cyclic Peptide Library is a powerful tool for drug discovery and PPI inhibitor screening.

HY-L922

Good ADMET Diversity Library

25000 compounds

A diverse compound library with favorable ADMET properties (Absorption, Distribution, Metabolism, Excretion, and Toxicity) is crucial in drug discovery. Early evaluation of ADMET properties allows for the exclusion of molecules with unfavorable profiles at the initial stages, thereby reducing the risk of late-stage development failures, lowering R&D costs, and accelerating optimization of lead compounds. Based on predictions from ADMET-related AI algorithms, the compounds in this library are predicted to exhibit favorable oral bioavailability (F > 30%), reasonable plasma protein binding (PPB < 98%), minimized CYP3A4 inhibition potential (inhibition probability < 50%, CYP3A4 is the most critical drug-metabolizing enzyme in the cytochrome P450 family) , low toxicity profiles, with 140 potentially toxic substructures pre-identified and excluded via substructure searching to eliminate compounds containing hazardous fragments. The diversity library enables broad applicability in high-throughput screening (HTS) and high-content screening (HCS).

HY-L214

Liposome Library

191 compounds

Liposomes are spherical or multilayered spherical vesicles formed by the self-assembly of diacyl chain phospholipids (lipid bilayers) in aqueous solutions, which can be made from natural or synthetic phospholipids and exhibit good biocompatibility and low toxicity. They can serve as delivery carriers for various bioactive substances (such as drugs, proteins, nucleic acids, etc.) and are widely used in biomedical and chemical research. The main advantages of liposomes include 1) Protective effect: Their bilayer structure can protect encapsulated molecules from enzymatic degradation, oxidation, and other influences, extending stability and activity; 2) Active targeting: Surface modifications enable active targeting, enhancing the concentration of drugs or molecules in specific tissues or cells; 3) Customizability: The composition and structure of liposomes can be adjusted according to needs, such as altering phospholipid types or adding targeting ligands. These properties make liposomes highly valuable in developing novel drug delivery systems, serving as nucleic acid carriers for gene transfection, studying cellular uptake mechanisms and drug release kinetics, as well as developing functional food additives to improve the bioavailability of nutritional components.

MCE contains 191 liposome compounds, which is a good tool for lipidomic-related studies.

Cat. No.	Product Name	Type

HY-D0711

Indocyanine green 40+ Cited Publications Foxgreen; IC Green; Cardiogreen	Fluorescent Dyes
Indocyanine green (Foxgreen) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography (Ex/Em = 785/813 nm) .

HY-D0985A

TMRE Maximum Cited Publications 75 Publications Verification Tetramethylrhodamine ethyl ester perchlorate	Fluorescent Dyes
Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .

HY-D0984A

TMRM Perchlorate 30+ Cited Publications T668	Fluorescent Dyes
Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .

HY-D0816

Rhodamine 123 25+ Cited Publications RH-123; R-22420	Fluorescent Dyes
Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .

HY-D0309

Rhodamine 6G 4 Publications Verification Basic Red 1	Fluorescent Dyes
Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .

HY-D1583

Cyanine5 DBCO hexafluorophosphate

4 Publications Verification

DBCO-Cy5 hexafluorophosphate; Cyanine5 dibenzocyclooctyne hexafluorophosphate

Fluorescent Dyes

Cyanine5 DBCO (DBCO-Cy5) hexafluorophosphate is a low-toxicity azide reactive probe (NIR fluorescent dye), for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO hexafluorophosphate has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO hexafluorophosphate can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .

HY-D0984

TMRM	Fluorescent Dyes
Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .

HY-DY1042

TMRM Perchlorate (solution)

Fluorescent Dyes

Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .
Solvent and concentration: DMSO: 10 mM

HY-D0711R

Indocyanine green (Standard) Foxgreen (Standard); IC Green (Standard); Cardiogreen (Standard)	Fluorescent Dyes
Indocyanine green (Standard) is the analytical standard of Indocyanine green. This product is intended for research and analytical applications. Indocyanine green (Foxgreen) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography .

HY-101876

Rhodamine 800	Fluorescent Dyes
Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .

HY-114354

BODIPY FL alkyne

BOD FL alkyne

Fluorescent Dyes

BODIPY (BOD) FL alkyne is an alkyne-containing BODIPY fluorophore derivative. BODIPY FL alkyne is a bioorthogonal labeling reagent with low toxicity and extremely low non-specific reactivity, and it is widely used in fluorescent bioimaging. BODIPY FL alkyne specifically labels azide groups on intracellular glycoconjugates mainly via strain-promoted azide-alkyne cycloaddition (SPAAC), or mediates site-specific conjugation with proteins such as IL-33, and supports positive cross-linking with other probes (e.g., DBCO-SCy5) for dual labeling. With the advantages of high specificity and low background interference, BODIPY FL alkyne can be used in the research of related diseases such as asthma, atopic dermatitis and inflammatory bowel disease .

HY-D1262

BODIPY-TS Thiol-green 2	Fluorescent Dyes
BODIPY-TS (Thiol-green 2) is a fast response and thiol-specific turn-on probe. BODIPY-TS utilizes the thiosulfonate scaffold as a thiol recognition unit. BODIPY-TS has low toxicity, and features high selectivity, low detection limit, and quantitative reaction to thiols . Ex: 490 nM; Em: 515 nM.

HY-DY1023

TMRE (solution)

Fluorescent Dyes

HY-D1456

TEPC466

Fluorescent Dyes

TEPC466 is a novel TEPP-46-based aggregation-induced emission (AIE) probe. TEPC466 shows a high degree of selectivity and sensitivity for the detection of PKM2 protein via the AIE effect. EPC466 can be used for the detection of PKM2. TEPC466 is successfully applied in imaging the PKM2 protein in colorectal cancer cells with low toxicity. TEPC466 is a useful tool for cancer diagnosis and research .

HY-D2188

IMP-2373

Fluorescent Dyes

IMP-2373 is a low-toxicity activity-based probe targeting covalent pan-deubiquitinase (DUB), which modulates and monitors DUB activity via covalent binding to the catalytic cysteine and active site of DUB. IMP-2373 enables real-time tracking of dynamic intracellular DUB activity in physiologically relevant living cell systems, and quantitative analysis of activity changes induced by pharmacological inhibition or MYC dysregulation. IMP-2373 can be used for research on related diseases such as B-cell lymphoma .

HY-DY1054

Rhodamine 123 (solution)

Fluorescent Dyes

HY-D2907

Cyanine 5 DBCO

DBCO-Cy5; Cyanine5 dibenzocyclooctyne

Fluorescent Dyes

Cyanine5 DBCO (DBCO-Cy5) is a low-toxicity azide reactive probe (NIR fluorescent dye), for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .

HY-D0309R

Rhodamine 6G (Standard)

Basic Red 1 (Standard)

Fluorescent Dyes

Rhodamine 6G (Standard) is the analytical standard of Rhodamine 6G. This product is intended for research and analytical applications. Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms .

HY-DY1027

Indocyanine green (solution)	Fluorescent Dyes
Indocyanine green (Foxgreen) (solution) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography (Ex/Em = 785/813 nm) . Solvent and concentration: DMSO: 10 mM

HY-DY1068

Cyanine5 DBCO hexafluorophosphate (solution)

Fluorescent Dyes

Cyanine5 DBCO (DBCO-Cy5) hexafluorophosphate (solution) is a low-toxicity azide reactive probe (NIR fluorescent dye) , for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO hexafluorophosphate has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO hexafluorophosphate can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .
Solvent and concentration: DMSO: 10 mM

HY-D1258

AC-green VDP-green	Fluorescent Dyes
AC-green (VDP-green) is a β-allyl carbamate fluorescent probe for specifically imaging vicinal dithiol proteins (VDPs) in living systems (λ_ex/λ_em=400/475 nm). AC-green can detect the reduced bovine serum albumin (rBSA) with high sensitivity. AC-green displays low toxicity and features high sensitivity, and is suitable for sensing VDPs in living cells and zebrafishes .

HY-D3153

PbQ

Fluorescent Dyes

PbQ is a tubulin inhibitor (with an IC₅₀ of 5 μM against goat tubulin) and a fluorescent probe for cuprous ions Cu (I). PbQ can penetrate the membrane of peripheral blood mononuclear cells, form a stable 1:1 complex with Cu ⁺ ions, and exhibits low toxicity and good biocompatibility toward macrophage cell lines. In addition, PbQ promotes tubulin degradation and disrupts the microtubule network in lung epithelial cells without affecting actin. PbQ also possesses genotoxicity by forming DNA base adducts, and it can activate caspase-3 and apoptosis-related genes, induce loss of mitochondrial membrane potential, and trigger cell apoptosis. PbQ can be used in studies related to chronic obstructive pulmonary disease .

Cat. No.	Product Name	Type

HY-W250168

Polyoxyethylene(10) oleyl ether

Polyethylene glycol oleyl ether, average Mn～709; Polyethylene glycol monooleyl ether, n～10

Biochemical Assay Reagents

Polyoxyethylene(10) oleyl ether, also known as POE(10) monooleate, is a nonionic surfactant consisting of a polyethylene glycol chain with 10 ethylene oxide units and an oleic acid residue. It has excellent emulsifying, wetting and dispersing properties, making it suitable for a variety of applications including personal care products and pharmaceutical formulations. POE(10) monooleate is commonly used as a solubilizer to improve the solubility and bioavailability of poorly soluble drugs. Furthermore, it is biodegradable and has low toxicity, making it an environmentally friendly ingredient suitable for various industrial applications.

HY-W010639

4-Penten-1-ol

Pent-4-en-1-ol

Biochemical Assay Reagents

4-Penten-1-ol is commonly used as a flavor ingredient in various products, including food, beverages, and perfumes, and can also be used as a starting material for the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. In addition, 4-Penten -1-ol has been investigated for its potential use as a biobased solvent due to its low toxicity and biodegradability, and its antimicrobial properties against certain bacteria and fungi, which may make it useful for developing new Antibacterial agents.

HY-W010532

trans-3-Hexenoic acid

(E)-Hex-3-enoic acid

Biochemical Assay Reagents

(E)-Hex-3-enoic acid is an unsaturated organic compound. It is commonly used as a fragrance ingredient in a variety of products, including food, beverages, and personal care products, and it can also be used as a starting material for the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. In addition, (E)-Hex- 3-enoic acid has been investigated for its potential use as a biobased solvent due to its low toxicity and biodegradability, as well as its potential antibacterial and antifungal properties, which may make it useful for developing new Antibacterial agents.

HY-W133920

Polypropylene glycol 2000 PPG 2000	Biochemical Assay Reagents
Polypropylene glycol 2000 (PPG 2000) is a polyether produced by ring-opening polymerization of propylene oxide. Polypropylene glycol 2000 has low toxicity, and acts as a dispersant for leather finishing materials, as well as a surfactant and wetting agent for pharmaceutical preparations .

HY-W250166

Polyoxyethylene tridecyl ether

Biochemical Assay Reagents

Poly(ethylene glycol) (12) tridecyl ether is a nonionic surfactant belonging to the family of ethoxylated fatty alcohols. It is commonly used as an emulsifier, solubilizer, and wetting agent in a variety of industrial and personal care products. Poly(ethylene glycol)(12) tridecyl ether has various properties that make it suitable for these applications, including its low toxicity, high solubility in water and organic solvents, and ability to stabilize emulsions. In addition, it can be used as a raw material for the production of other surfactants and specialty chemicals.

HY-W393372

THAM maleate 1 Publications Verification Tris maleate; Tris(hydroxymethyl)aminomethane maleate	Biochemical Assay Reagents
THAM (Tris) maleate is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. THAM maleate is an effective amine compound for pH control in the physiological range .

HY-D0227J

THAM hydrochloride (≥99%, for cell culture)

1 Publications Verification

Tris HCl (≥99%, for cell culture); Tris hydrochloride (≥99%, for cell culture)

Biochemical Assay Reagents

THAM hydrochloride (≥99%, for cell culture) is a low-toxicity amino alcohol buffer, a specific CO₂-consuming proton acceptor that buffers carbon dioxide and acid both in vitro and in vivo. THAM hydrochloride (≥99%, for cell culture) binds protons to form bicarbonate, reduces PaCO₂, and induces intracellular alkalization, thereby ameliorating hypercapnia-induced elevation of pulmonary blood vessels and pulmonary arterial pressure. THAM hydrochloride (≥99%, for cell culture) may cause PaCO₂ rebound, hypoglycemia, and respiratory depression. THAM hydrochloride (≥99%, for cell culture) removes amniotic epithelium and preserves the basement membrane, but depletes extracellular matrix and reduces the adhesion rate of limbal epithelial cells. THAM hydrochloride (≥99%, for cell culture) can act as a CO₂ carrier to enhance the productivity and carbon utilization rate of Scenedesmus obliquus. THAM hydrochloride (≥99%, for cell culture) is a key component of buffer solutions used in various biological, cell culture, biochemical, and molecular biology applications .

HY-W460471

Tris Buffered Saline

Biochemical Assay Reagents

Tris Buffered Saline is a common buffer reagent in molecular biology, consisting of Tris and NaCl. Tris Buffered Saline can adjust pH and ionic strength and is widely used in DNA/RNA extraction, PCR and protein electrophoresis. Tris Buffered Saline can purify and protect nucleic acid materials and improve reaction efficiency and concentration. In protein electrophoresis, Tris Buffered Saline stabilizes gels and maintains pH. Overall, Tris Buffered Saline offers versatility, good solubility, and low toxicity in molecular biology applications.

HY-158222A

Alginate Methacryloyl (MW 300000)

AlgMA (MW 300000)

Biochemical Assay Reagents

Alginate Methacryloyl (MW 300000) is a methacryloyl alginate with potential for use as a tissue engineering scaffold and 3D printing ink. Alginate Methacryloyl (MW 300000) is biocompatible, non-immunogenic, has low toxicity and is capable of physical cross-linking with divalent cations such as calcium . Alginate Methacryloyl (MW 300000) needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity.
Application: cell culture, biological 3D printing, tissue engineering, etc.

HY-W004705

(2-Aminophenyl)methanol 2-Hydroxymethylaniline	Biochemical Assay Reagents
(2-Aminophenyl)methanol (2-Hydroxymethylaniline) is a molecular chaperone to rescue P123S mutant pendrin. (2-Aminophenyl)methanol has the advantages of low dose, long-term effect and low toxicity. (2-Aminophenyl)methanol can be used for the study of Pendred syndrome (a syndromic deafness) .

HY-158222

Alginate Methacryloyl (MW 50000)

AlgMA (MW 50000)

Biochemical Assay Reagents

Alginate Methacryloyl (MW 50000) is a methacryloyl alginate with potential for use as a tissue engineering scaffold and 3D printing ink. Alginate Methacryloyl (MW 50000) is biocompatible, non-immunogenic, has low toxicity and is capable of physical cross-linking with divalent cations such as calcium . Alginate Methacryloyl (MW 50000) needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity.
Application: cell culture, biological 3D printing, tissue engineering, etc.

HY-Y0383

Dimethyl terephthalate	Biochemical Assay Reagents
Dimethyl terephthalate is a low toxicity, low volatility industrial chemical widely used in the production of polyester fibers and films .

HY-W010202

Dihydrolinalool

3,7-Dimethyloct-6-en-3-ol

Biochemical Assay Reagents

Dihydrolinalool, Dihydrolinalool is commonly used as a flavor ingredient in various products, including food, beverages, and perfumes, and it can also be used as a base material for the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. In addition, due to Dihydrolinalool's low toxicity and Biodegradability, which has been studied for its potential use as a bio-based solvent, has also been studied for its potential antioxidant and anti-inflammatory properties, which may make it useful in the study of various diseases, including cancer and Alzheimer's disease. Alzheimer's disease.

HY-W014226

4,4'-Dihydroxybenzophenone

Biochemical Assay Reagents

4,4'-Dihydroxybenzophenone is a type of phenolic ultraviolet absorber and a drug intermediate for synthesis of various anticancer active compounds (such as Sivifene (HY-14801)). 4,4'-Dihydroxybenzophenone binds to the active site of trypsin with binding constants (K_A = 7.59 x 10 ⁵ L/moL) and leads to abnormal structure of trypsin, suggesting that long-term intake may affect the digestive function of the human body. 4,4’-dihydroxybenzophenone has a relatively low toxicity to Chlorella vulgaris and a moderate toxicity to Daphnia magna .

HY-Y1013

5-Bromonicotinic acid	Biochemical Assay Reagents
5-Bromonicotinic acid can be used as a pharmaceutical intermediate to synthesize 5-aryloyl nicotinic acid compounds. 5-Bromonicotinic acid has the characteristics of good drug similarity, high oral bioavailability, and low toxicity through molecular docking prediction. 5-Bromonicotinic acid has good binding ability with hepatitis virus proteins (binding energy: -4.7 to -5.3 kcal/mol) .

HY-W010177

Ethyl heptanoate

Biochemical Assay Reagents

Ethyl heptanoate, Ethyl heptanoate is commonly used as a fragrance ingredient in a variety of products, including food, beverages, and personal care products, it can also be used as a solvent, and a building block for the synthesis of various organic compounds, including pharmaceuticals and agrochemicals, in addition , due to its low toxicity and biodegradability, Ethyl heptanoate has been investigated for its potential use as a bio-based solvent, as well as for its potential antimicrobial properties against certain bacteria and fungi.

HY-173381A

Cholesteryl-PEG1000-Biotin Cholesteryl biotinyl(polyethyleneglycol)-1000 carbamate	Biochemical Assay Reagents
Cholesteryl-PEG1000-Biotin is a lipid product. Cholesteryl-PEG1000-Biotin is a cholesterol backbone attached to one side of a PEG unit and a Biotin unit on the other side. Biotin is an enzyme cofactor that can be used to label proteins, and PEG is a low-toxic, hydrophilic, water-soluble polymer. Cholesteryl-PEG1000-Biotin can be used for drug circulation time studies .

HY-166997

AL-A12	Biochemical Assay Reagents
AL-A12 is a short-chain amino lipid with high gene delivery efficiency and low toxicity, and can be used in drug delivery research .

HY-Y0383R

Dimethyl terephthalate (Standard)	Biochemical Assay Reagents
Dimethyl terephthalate (Standard) is the analytical standard of Dimethyl terephthalate. This product is intended for research and analytical applications. Dimethyl terephthalate is a low toxicity, low volatility industrial chemical widely used in the production of polyester fibers and films .

HY-147207C

Phospholipid-PEG5000-Biotin	Biochemical Assay Reagents
Phospholipid-PEG5000-Biotin is a phospholipid PEG derivative, can be used for modify liposome and cells surface, and pancreatic islets for cell transplantation. Phospholipid is a class of lipid containing a hydrophilic “head” and two hydrophobic “tails”; PEG is a hydrophilic and water-soluble polymer with low toxicity; Biotin is an enzyme co-factor, can be used for labeling protein .

HY-147207A

Phospholipid-PEG2000-Biotin

Biochemical Assay Reagents

Phospholipid-PEG2000-Biotin is a Biotin labeled phospholipid PEG derivative, can be used for modify liposome and cells surface, and pancreatic islets for cell transplantation. Phospholipid is a class of lipid containing a hydrophilic "head" and two hydrophobic "tails" ; PEG is a hydrophilic and water-soluble polymer with low toxicity; Biotin is an enzyme co-factor, can be used for labeling protein .

HY-Y1013R

5-Bromonicotinic acid (Standard)

Biochemical Assay Reagents

5-Bromonicotinic acid (Standard) is the analytical standard of 5-Bromonicotinic acid. This product is intended for research and analytical applications. 5-Bromonicotinic acid can be used as a pharmaceutical intermediate to synthesize 5-aryloyl nicotinic acid compounds. 5-Bromonicotinic acid has the characteristics of good drug similarity, high oral bioavailability, and low toxicity through molecular docking prediction. 5-Bromonicotinic acid has good binding ability with hepatitis virus proteins (binding energy: -4.7 to -5.3 kcal/mol) .

Cat. No.	Product Name	Target	Research Area

HY-P5307

Peptide A5K INF7-A5K-TAT	Biochemical Assay Reagents	Others
Peptide A5K (INF7-A5K-TAT) is an amphiphilic peptide derived from the HA2-TAT fusion scaffold. Peptide A5K can non-covalently bind to CRISPR ribonucleoproteins and efficiently deliver them to cells, such as primary human T cells, B cells, and NK cells. Peptide A5K enables low-toxicity, precise, and multiplex genome editing, holding great application potential in the field of cell therapy .

HY-W250166

Polyoxyethylene tridecyl ether	Environmental Pollutants Biochemical Assay Reagents	Others
Poly(ethylene glycol) (12) tridecyl ether is a nonionic surfactant belonging to the family of ethoxylated fatty alcohols. It is commonly used as an emulsifier, solubilizer, and wetting agent in a variety of industrial and personal care products. Poly(ethylene glycol)(12) tridecyl ether has various properties that make it suitable for these applications, including its low toxicity, high solubility in water and organic solvents, and ability to stabilize emulsions. In addition, it can be used as a raw material for the production of other surfactants and specialty chemicals.

HY-P11099

Cys-LT7	Transferrin Receptor	Neurological Disease Cancer
Cys-LT7 is a transferrin receptor (TfR)-targeting peptide ligand. Cys-LT7 binds to a TfR site distinct from endogenous transferrin, mediates conjugated Doxorubicin (HY-15142A) delivery to TfR-overexpressed tumor cells, and exhibits low toxicity to TfR-low-expressed normal cells. Cys-LT7 is an L-configuration peptide susceptible to proteolytic enzymes, leading to poor biostability in peptide-drug conjugates. Cys-LT7 can be used for the research of glioblastoma, hepatocellular carcinoma, lung carcinoma .

HY-P11308

Cys-GE11	EGFR	Cancer
Cys-GE11 is an N-terminal modified GE11 (HY-P10128) with cysteine (Cys) added. Cys-GE11 can be coupled through the thiol group of Cys. Cys-GE11 can be linked to PEG-P (TMC-DTC) through the N-terminus of cysteine to form a targeted polymer. Cys-GE11 can target cells with high EGFR expression (such as SMMC-7721 cells). Cys-GE11 can significantly enhance drug enrichment at the tumor site and exhibit low toxicity .

HY-Y1091

D-Lysine	Endogenous Metabolite	Others
D-Lysine is a useful raw material employed as an analog of lutenizing-hormone-releasing hormone and as a agent carrier in the form of polylysine. D-Lysine decreases renal uptake of radioactivity during scintigraphy and PRRT with low toxicity. D-Lysine not interferes with the natural amino acid metabolic balance .

HY-113003

H-γ-Glu-Gln-OH γ-Glutamylglutamine; γ-Glu-Gln	Peptides	Others Cancer
H-γ-Glu-Gln-OH is a hydrophilic peptide and can be conjugated to drugs. The carrier composed of H-γ-Glu-Gln-OH has the characteristics of high water solubility and drug-loading capacity, good biocompatibility, low toxicity, improved tumor targeting ability, and anti-tumor efficacy .

HY-P5640

Tritrpticin	Bacterial Parasite	Infection
Tritrpticin is a porcine-derived antimicrobial peptide with properties such as membrane disruption and hemolysis. Tritrpticin disrupts the cell membranes of bacteria, fungi and Jurkat T cell leukemia cells and induces their death. Tritrpticin also enhances the efficacy of Metronidazole (HY-B0318) against Trichomonas vaginalis, reduces plasma endotoxin and inflammatory cytokine levels, restricts bacterial growth in blood and visceral tissues, decreases the mortality rate of septic shock in rats and enhances the therapeutic effect of ertapenem. Tritrpticin exhibits selective cytotoxicity against Jurkat T cell leukemia cells, while showing low toxicity to normal peripheral blood mononuclear cells and red blood cells, and can serve as a template for antimicrobial peptide design. Tritrpticin can be applied to research related to bacterial infections, fungal infections, trichomoniasis, septic shock and leukemia .

HY-P3912A

Endotoxin inhibitor TFA	Interleukin Related	Infection
Endotoxin inhibitor TFA is a synthetic peptide that binds lipid A with high affinity, thereby detoxifying LPS (HY-D1056) and preventing LPS-induced cytokine release in vivo. Endotoxin inhibitor TFA inhibits the febrile response to LPS with very low toxicity and lethality .

HY-P3350

LS-BF1	Bacterial	Infection
LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].

HY-P5307A

Peptide A5K acetate INF7-A5K-TAT acetate	Biochemical Assay Reagents	Others
Peptide A5K (INF7-A5K-TAT) acetate is an amphiphilic peptide derived from the HA2-TAT fusion scaffold. Peptide A5K acetate can non-covalently bind to CRISPR ribonucleoproteins and efficiently deliver them to cells, such as primary human T cells, B cells, and NK cells. Peptide A5K acetate enables low-toxicity, precise, and multiplex genome editing, holding great application potential in the field of cell therapy .

HY-P3912

Endotoxin inhibitor	COX Interleukin Related	Infection
Endotoxin inhibitor a synthetic peptide that binds lipid A with high affinity, thereby detoxifying LPS (HY-D1056) and preventing LPS-induced cytokine release in vivo. Endotoxin inhibitor inhibits the febrile response to LPS with very low toxicity and lethality .

HY-W024485

SARS-CoV-2-IN-86	SARS-CoV Drug Derivative	Infection
SARS-CoV-2-IN-86 (Compound 2734589) is SARS-CoV-2 methyltransferases nsp14 and nsp16 inhibitor, Andrographolide (HY-N0191) derivative. SARS-CoV-2-IN-86 has low toxicity, and according to toxicity analysis, the predicted LD50 is 700 mg/kg .

HY-P11064

G(IIKK)3I-NH2	Bacterial	Infection
G(IIKK)3I-NH2 is an antimicrobial peptide. G(IIKK)3I-NH2 exhibits potent antibacterial activity against both Gram-negative and Gram-positive bacteria. G(IIKK)3I-NH2 has low toxicity to primary cells and mice, and G(IIKK)3I-NH2 is not easy to induce bacterial resistance. G(IIKK)3I-NH2 can be used in the research of anti-infection agents .

HY-P11247

NOTA-SFCVHEM	Peptides	Cancer
NOTA-SFCVHEM can be activated by CTB. NOTA-SFCVHEM can be used to prepare PET tracer. NOTA-SFCVHEM has good stability, low toxicity, high tumor selectivity, and low liver accumulation .

HY-P10539

Hp1404	Bacterial	Infection
Hp1404 is a novel cationic antimicrobial peptide. Hp1404 has specific inhibitory activity against Gram-positive bacteria, including Staphylococcus aureus (MRSA) resistant to Laburnetin (HY-N7382). Hp1404 has antimicrobial activity, low toxicity, and is not prone to drug resistance, and can be used in the research of antimicrobial agents .

HY-P10669

NDI-Lyso	Caspase Apoptosis	Cancer
NDI-Lyso is a lysosome-targeted anticancer agent that induces the formation of rigid long fibers in cancer cell lysosomes through an enzyme-instructed self-assembly (EISA) mechanism catalyzed by cathepsin B. This process triggers lysosomal swelling, membrane permeabilization (LMP), and membrane disruption, ultimately leading to cancer cell apoptosis via a non-classical caspase-independent pathway. NDI-Lyso exhibits significant selective anticancer activity in various cancer cell lines and drug-resistant cancer cells (IC₅₀ ~10 μM) while showing low toxicity to normal cells (IC₅₀ > 60 μM) .

HY-P11634

KF-22	Bacterial	Infection
KF-22 is an antimicrobial peptide that exhibits antimicrobial activity against both Gram-negative and Gram-positive bacteria. KF-22 demonstrates broad-spectrum, potent activity against multidrug-resistant bacteria with low toxicity. KF-22 can be used in research related to infections .

HY-P11657

GN-2 peptoid	Bacterial	Infection
GN-2 peptoid is a 9-mer cationic amphipathic peptoid and bactericidal agent with an overall net charge of +4, broad-spectrum antimicrobial activity, and low hemolytic and cytotoxic activity against mammalian cells. GN-2 peptoid exerts bactericidal action against Escherichia coli in a concentration-dependent manner. GN-2 peptoid exhibits antimicrobial activity against Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli, Pseudomonas aeruginosa strains. GN-2 peptoid shows low toxicity against human red blood cells and HeLa cells. GN-2 peptoid maintains antimicrobial activity in the presence of 50% human blood plasma. GN-2 peptoid can be used for the research of bacterial infections .

Cat. No.	Product Name

HY-K2014

PEI Transfection Reagent

50+ Cited Publications

MCE PEI Transfection Reagent is designed based on 25 kDa PEI. It has high-efficiency, low-toxicity, strong-stability, and is suitable for many cell types, such as HEK-293、HEK-293T、CHO-K1、COS-1、COS-7、NIH/3T3、Sf9、HepG2 and HeLa et, even some hard-to-transfect cells. It can also be applied to large-scale recombinant protein expression and virus production. The 1 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

HY-K0608

Masson Staining Kit

MCE Masson Staining Kit can simultaneously stain various tissue components, such as cell nuclei, collagen fibers, and muscle fibers. It features low toxicity, environmental friendliness, simple operation, and stable performance. The staining results show clear coloration and high contrast. The stained sections can be stored for long periods with minimal fading, facilitating long-term preservation and image analysis. This kit is widely used in studies of connective tissue, muscle tissue, and collagen fibers, and is suitable for histological observation and related pathological analyses.

HY-K0609

Modified Masson Staining Kit

MCE Modified Masson Staining Kit employs Celestine Blue hematoxylin for light nuclear staining, offering shorter differentiation time compared to conventional methods. It features low toxicity, environmental friendliness, simple operation, and stable performance. The staining results show clear coloration and high contrast. The stained sections can be stored for long periods with minimal fading, facilitating long-term preservation and image analysis. This kit is widely used in studies of connective tissue, muscle tissue, and collagen fibers, and is suitable for histological observation and related pathological analyses.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N1445

Isoquercitrin 5+ Cited Publications Isoquercetin; Quercetin 3-glucoside	Apocynaceae Flavonols Flavonoids Classification of Application Fields Phenols Polyphenols Plants Apocynum venetum Linn. Disease Research Fields Source Classification Cancer	NF-κB NO Synthase
Isoquercetin (Quercetin 3-glucoside) is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties. Isoquercetin alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway . Isoquercetin regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system. Isoquercetin has high bioavailability and low toxicity, is a promising candidate agent to prevent birth defects in diabetic pregnancies .

HY-N0462

Corilagin Maximum Cited Publications 8 Publications Verification NP-004255	Phyllanthus urinaria Linn. Infection Structural Classification Classification of Application Fields Phenols Polyphenols Euphorbiaceae Plants Inflammation/Immunology Disease Research Fields Source Classification	Toll-like Receptor (TLR) Reverse Transcriptase Bacterial Apoptosis Autophagy
Corilagin, a gallotannin, has anti-tumor, anti-inflammatory and hepatoprotective activities. Corilagin inhibits activity of reverse transcriptase of RNA tumor viruses. Corilagin also inhibits the growth of Staphylococcus aureus with a MIC of 25 μg/mL. Corilagin shows anti-tumor activity on hepatocellular carcinoma and ovarian cancer model. Corilagin shows low toxicity to normal cells and tissues .

HY-W017522

Adipic acid Hexanedioic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Endocrine diseases Metabolic Disease Endogenous metabolite Disease Research Fields Cardiovascular System Disorder Cancer Source Classification	Environmental Pollutants Endogenous Metabolite HSV
Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc .

HY-W009141

1-Monopalmitin Glyceryl palmitate	Plants Source Classification	P-glycoprotein IAP PI3K Akt Caspase Apoptosis
1-Monopalmitin (Glyceryl palmitate) is an activator of the PI3K/Akt pathway and an inhibitor of P-glycoprotein (P-gp). 1-Monopalmitin can induce G2/M arrest and caspase-dependent apoptosis in cancer cells, while inhibiting IAPs protein expression. 1-Monopalmitin can increase drug accumulation by inhibiting P-gp activity in intestinal Caco-2 cells. 1-Monopalmitin has the ability to induce protective autophagy and apoptosis of lung cancer cells (IC₅₀=50-58 μg/mL), with low toxicity to normal cells .

HY-N10508

Calcitroic acid	Ketones, Aldehydes, Acids Endogenous metabolite	Drug Metabolite VD/VDR
Calcitroic acid is a vitamin D receptor (VDR) agonist that can activate VDR-mediated transcription. Calcitroic acid is the main metabolite of 1,25-dihydroxyvitamin D3, with the highest concentrations found in the liver and mucosa of mice, and it has metabolic stability and very low toxicity .

HY-Y1091

D-Lysine	Classification of Application Fields Other Diseases Amino acids Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
D-Lysine is a useful raw material employed as an analog of lutenizing-hormone-releasing hormone and as a agent carrier in the form of polylysine. D-Lysine decreases renal uptake of radioactivity during scintigraphy and PRRT with low toxicity. D-Lysine not interferes with the natural amino acid metabolic balance .

HY-113003

H-γ-Glu-Gln-OH γ-Glutamylglutamine; γ-Glu-Gln	Animals Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Others
H-γ-Glu-Gln-OH is a hydrophilic peptide and can be conjugated to drugs. The carrier composed of H-γ-Glu-Gln-OH has the characteristics of high water solubility and drug-loading capacity, good biocompatibility, low toxicity, improved tumor targeting ability, and anti-tumor efficacy .

HY-N1445R

Isoquercitrin (Standard) 1 Publications Verification Isoquercetin (Standard); Quercetin 3-glucoside (Standard)	Apocynaceae Flavonols Structural Classification Flavonoids Phenols Polyphenols Plants Apocynum venetum Linn. Source Classification	Reference Standards NF-κB NO Synthase
Isoquercetin (Standard) is the analytical standard of Isoquercetin. This product is intended for research and analytical applications. Isoquercetin (Quercetin 3-glucoside) is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties. Isoquercetin alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway . Isoquercetin regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system. Isoquercetin has high bioavailability and low toxicity, is a promising candidate agent to prevent birth defects in diabetic pregnancies .

HY-N5058

Dehydroeffusol	Natural Products Juncus effusus Linn. Juncaceae Classification of Application Fields Phenols Polyphenols Plants Disease Research Fields Source Classification Cancer	Apoptosis
Dehydroeffusol is a phenanthrene from medicinal herb Juncus effuses. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. It shows very low toxicity .

HY-N0462R

Corilagin (Standard) NP-004255 (Standard)	Phyllanthus urinaria Linn. Structural Classification Phenols Polyphenols Euphorbiaceae Plants Source Classification	Toll-like Receptor (TLR) Reference Standards Reverse Transcriptase Bacterial Apoptosis Autophagy
Corilagin (Standard) is the analytical standard of Corilagin. This product is intended for research and analytical applications. Corilagin, a gallotannin, has anti-tumor, anti-inflammatory and hepatoprotective activities. Corilagin inhibits activity of reverse transcriptase of RNA tumor viruses. Corilagin also inhibits the growth of Staphylococcus aureus with a MIC of 25 μg/mL. Corilagin shows anti-tumor activity on hepatocellular carcinoma and ovarian cancer model. Corilagin shows low toxicity to normal cells and tissues .

HY-N12461

Cucurbitacin F	Triterpenes Structural Classification Hemsleya gigantha W. J. Chang Terpenoids Cucurbitaceae Plants Source Classification	Bacterial Caspase Apoptosis
Cucurbitacin F is a tetracyclic protostane-type triterpenoid with low toxicity, antibacterial and anti-inflammatory activities, and is also a related compound of Cucurbitacin B (HY-N0416). Cucurbitacin F widely exists in plants such as Cucurbitaceae plants, Quisqualis indica and Sorbaria sorbifolia. Cucurbitacin F acts as an actin aggregator and reduces cell viability in a dose-dependent manner. Cucurbitacin F induces apoptosis by triggering G2/M phase cell cycle arrest and activating the caspase-3-dependent apoptosis .

HY-118992

Aurodox X 5108; Goldinomycin	Infection Microorganisms Classification of Application Fields Antibiotics Disease Research Fields Other Antibiotics Source Classification	Antibiotic Bacterial
Aurodox (X 5108) is an antibiotic obtained from a streptomyces variant, Aurodox can against a number of gram-positive bacteria. Aurodox shows a very *low toxicity* in mice and promoted poultry growth .

HY-W010202

Dihydrolinalool 3,7-Dimethyloct-6-en-3-ol	Amomum subulatum Roxb. Structural Classification Natural Products Plants Source Classification Zingiberaceae	Environmental Pollutants
Dihydrolinalool, Dihydrolinalool is commonly used as a flavor ingredient in various products, including food, beverages, and perfumes, and it can also be used as a base material for the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. In addition, due to Dihydrolinalool's low toxicity and Biodegradability, which has been studied for its potential use as a bio-based solvent, has also been studied for its potential antioxidant and anti-inflammatory properties, which may make it useful in the study of various diseases, including cancer and Alzheimer's disease. Alzheimer's disease.

HY-135525

Agroclavine	Infection Structural Classification Alkaloids Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Endogenous metabolite Disease Research Fields Indole Alkaloids Source Classification Cancer	Dopamine Receptor Adrenergic Receptor
Agroclavine acts as an agonist of the D1-dopamine receptor and α₁-adrenergic receptor. Agroclavine enhances the sensitivity of the brain to magnetic fields; it impairs spatial memory without affecting hippocampal long-term potentiation (LTP). Agroclavine exerts bidirectional regulatory effects on immune activity: it enhances NK cell activity with low toxicity under normal conditions, while it inhibits NK cell activity and exhibits significant cardiac and hepatic toxicity under stress conditions. Agroclavine can be used for research on neuroelectrophysiology, learning and memory, and immunoregulation .

HY-N7262

Hydroxyvalerenic acid	Classification of Application Fields Ketones, Aldehydes, Acids Valeriana officinalis Linn. Plants Valerianaceae Disease Research Fields Cancer Source Classification	Others
Hydroxyvalerenic acid is isolated from Verbena officinalis, has a low toxicity with IC₅₀ values of 123 and 165 μM against GLC4 and COLO 320 cells, respectively .

HY-W017522R

Adipic acid (Standard) Hexanedioic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Disease markers Endocrine diseases Endogenous metabolite Cardiovascular System Disorder Cancer Source Classification	Reference Standards Endogenous Metabolite HSV
Adipic acid (Standard) (Hexanedioic acid (Standard)) is the analytical standard of Adipic acid (HY-W017522). This product is intended for research and analytical applications. Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc .

HY-W010177

Ethyl heptanoate	Source Classification	Environmental Pollutants Biochemical Assay Reagents
Ethyl heptanoate, Ethyl heptanoate is commonly used as a fragrance ingredient in a variety of products, including food, beverages, and personal care products, it can also be used as a solvent, and a building block for the synthesis of various organic compounds, including pharmaceuticals and agrochemicals, in addition , due to its low toxicity and biodegradability, Ethyl heptanoate has been investigated for its potential use as a bio-based solvent, as well as for its potential antimicrobial properties against certain bacteria and fungi.

HY-N6640

2-O-Acetyl-20-hydroxyecdysone 20-Hydroxyeedysone 2-acetate	other families Plants Steroids Source Classification	Amyloid-β
2-O-Acetyl-20-hydroxyecdysone, an ecdysterones in insects and terrestrial plants, inhibits amyloid-β₄₂ (Aβ₄₂)-induced cytotoxicity. 2-O-Acetyl-20-hydroxyecdysone could decrease Aβ oligomer formation through promotion of fibrogenesis, transforming Aβ oligomers to the low-toxicity fibrils .

HY-129347

Lankacyclinol A T-2636E	Microorganisms Antibiotics Source Classification	Antibiotic Bacterial
Lankacyclinol A is an orally active antibiotic isolated from Streptomyces rochei. Lankacyclinol A has broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria. Lankacyclinol A exhibits low toxicity in mice .

HY-N14407

Phenazostatin C	Microorganisms Antibiotics Other Antibiotics Source Classification	Others
Phenazostatin C can protect N18-RE-105 nerve cells from glutamate toxicity with an EC₅₀ of 0.37 μM and inhibit lipid peroxidation. Phenazostatin C has low toxicity, and 100 μM of Phenazostatin C is not cytotoxic .

HY-W009141R

1-Monopalmitin (Standard) Glyceryl palmitate (Standard)	Plants Source Classification	Reference Standards Apoptosis P-glycoprotein PI3K IAP Caspase Akt
1-Monopalmitin (Glyceryl palmitate) (Standard) is the analytical standard of 1-Monopalmitin (HY-W009141). This product is intended for research and analytical applications. 1-Monopalmitin (Glyceryl palmitate) is an activator of the PI3K/Akt pathway and an inhibitor of P-glycoprotein (P-gp). 1-Monopalmitin can induce G2/M arrest and caspase-dependent apoptosis in cancer cells, while inhibiting IAPs protein expression. 1-Monopalmitin can increase drug accumulation by inhibiting P-gp activity in intestinal Caco-2 cells. 1-Monopalmitin has the ability to induce protective autophagy and apoptosis of lung cancer cells (IC₅₀=50-58 μg/mL), with low toxicity to normal cells .

HY-N7262R

Hydroxyvalerenic acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Valeriana officinalis Linn. Plants Valerianaceae Source Classification	Reference Standards Others
Hydroxyvalerenic acid (Standard) is the analytical standard of Hydroxyvalerenic acid. This product is intended for research and analytical applications. Hydroxyvalerenic acid is isolated from Verbena officinalis, has a low toxicity with IC50 values of 123 and 165 μM against GLC4 and COLO 320 cells, respectively .

HY-172745

Conglobatin B1	Natural Products Microorganisms Source Classification	Others
Conglobatin B1 is a compound that can be isolated from Australian Streptomyces MST-91080. Conglobatin B1 is cytotoxic to the NS-1 myeloma cell line with an IC₅₀ of 0.084 μg/mL, but has low toxicity to NFF human fibroblasts. Conglobatin B1 can be used in the study of cancer .

HY-W010415

Prenyl acetate	Structural Classification Natural Products Rosaceae Plants Source Classification	Environmental Pollutants Insecticide
Prenyl acetate is an insecticide. At low concentrations, prenyl acetate exhibits an attractant effect on worker ants of the red imported fire ant, and it elicits strong antennal electroantennogram (EAG) responses in all castes of the red imported fire ant. Prenyl acetate shows low toxicity to mammals. It can be used in research related to the control of the red imported fire ant (Solenopsis invicta) .

Cat. No.	Product Name	Chemical Structure

HY-W017522S4

Adipic acid-d8
Adipic acid-d₈ (Hexanedioic acid-d₈) is the deuterium labeled Adipic acid (HY-W017522). Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc .

HY-W017522S3

Adipic acid-13C
Adipic acid- ¹³C (Hexanedioic acid- ¹³C) is the ¹³C labeled Adipic acid (HY-W017522). Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc .

HY-W017522S

Adipic acid-d10
Adipic acid-d₁₀ (Hexanedioic acid-d₁₀) is the deuterium labeled Adipic acid (HY-W017522). Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc .

HY-W017522S1

Adipic acid-13C6
Adipic acid- ¹³C₆ (Hexanedioic acid- ¹³C₆) is the ¹³C labeled Adipic acid (HY-W017522). Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc .

HY-W017522S2

Adipic acid-d4
Adipic acid-d₄ (Hexanedioic acid-d₄) is the deuterium labeled Adipic acid (HY-W017522). Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc .

HY-Y0383S2

Dimethyl terephthalate-13C2-1
Dimethyl terephthalate- ¹³C₂-1 is ¹³C labeled Dimethyl terephthalate. Dimethyl terephthalate is a low toxicity, low volatility industrial chemical widely used in the production of polyester fibers and films .

HY-118165S

Phenthoate-d6
Phenthoate-d₆ is deuterium labeled Phenthoate. Phenthoate is an organophosphorus pesticide having low toxicity in animals. Phenthoate is also a AChE inhibitor .

HY-126199S

(Z)-Tetrachlorvinphos-d6
(Z)-Tetrachlorvinphos-d₆ is the deuterium labeled Tetrachlorvinphos (HY-126199). Tetrachlorvinphos is an organophosphorus pesticide that has the activity of inhibiting cholinesterase. Tetrachlorvinphos is used as a pesticide, mainly for the control of pests. Tetrachlorvinphos has low toxicity to mammals .

HY-B1217S

Bronopol-d4
Bronopol-d₄ is deuterium labeled Bronopol. Bronopol is an antibacterial agent with low toxicity (to mammals) and high activity (especially against Gram-negative bacteria). Bronopol oxidizes protein thiols, inhibits enzymatic activity, and exhibits antibacterial activity. Bronopol is also a formaldehyde releaser ^.

HY-D0711S2

Indocyanine green-d7
Indocyanine green-d7 (Foxgreen-d7) is the deuterium labeled Indocyanine green (HY-D0711). Indocyanine green is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography .

HY-W017522S6

Adipic acid-13C2
Adipic acid- ¹³C₂ (Hexanedioic acid- ¹³C₂) is ¹³C labeled Adipic acid (HY-W017522). Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc .

HY-W017522S5

Adipic acid-d4-1
Adipic acid-d₄-1 (Hexanedioic acid-d₄-1) is the deuterium labeled Adipic acid (HY-W017522). Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc .

HY-Y0383S

Dimethyl terephthalate-d4
Dimethyl terephthalate-d₄ is the deuterium labeled Dimethyl terephthalate. Dimethyl terephthalate is a low toxicity, low volatility industrial chemical widely used in the production of polyester fibers and films .

HY-N10508S

Calcitroic acid-13C
Calcitroic acid- ¹³C is the ¹³C-labeled Calcitroic acid (HY-N10508). Calcitroic acid is a vitamin D receptor (VDR) agonist that can activate VDR-mediated transcription. Calcitroic acid is the main metabolite of 1,25-dihydroxyvitamin D3, with the highest concentrations found in the liver and mucosa of mice, and it has metabolic stability and very low toxicity .

HY-178400S

Ethyl heptanoate-d13

Ethyl heptanoate-d₁₃ is the deuterium labeled Ethyl heptanoate (HY-W010177). Ethyl heptanoate, Ethyl heptanoate is commonly used as a fragrance ingredient in a variety of products, including food, beverages, and personal care products, it can also be used as a solvent, and a building block for the synthesis of various organic compounds, including pharmaceuticals and agrochemicals, in addition , due to its low toxicity and biodegradability, Ethyl heptanoate has been investigated for its potential use as a bio-based solvent, as well as for its potential antimicrobial properties against certain bacteria and fungi.

HY-W009141S

1-Monopalmitin-d31

1-Monopalmitin-d₃₁ (Glyceryl palmitate-d₃₁) is the deuterium labeled 1-Monopalmitin (HY-W009141). 1-Monopalmitin (Glyceryl palmitate) is an activator of the PI3K/Akt pathway and an inhibitor of P-glycoprotein (P-gp). 1-Monopalmitin can induce G2/M arrest and caspase-dependent apoptosis in cancer cells, while inhibiting IAPs protein expression. 1-Monopalmitin can increase drug accumulation by inhibiting P-gp activity in intestinal Caco-2 cells. 1-Monopalmitin has the ability to induce protective autophagy and apoptosis of lung cancer cells (IC₅₀=50-58 μg/mL), with low toxicity to normal cells .

HY-W010639S

4-Penten-ol-d9

4-Penten-ol-d₉ (Pent-4-en-1-ol-d₉) is the deuterium labeled 4-Penten-1-ol (HY-W010639). 4-Penten-1-ol is commonly used as a flavor ingredient in various products, including food, beverages, and perfumes, and can also be used as a starting material for the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. In addition, 4-Penten -1-ol has been investigated for its potential use as a biobased solvent due to its low toxicity and biodegradability, and its antimicrobial properties against certain bacteria and fungi, which may make it useful for developing new Antibacterial agents.

Cat. No.	Product Name		Classification

HY-D1583

Cyanine5 DBCO hexafluorophosphate 4 Publications Verification DBCO-Cy5 hexafluorophosphate; Cyanine5 dibenzocyclooctyne hexafluorophosphate		DBCO
Cyanine5 DBCO (DBCO-Cy5) hexafluorophosphate is a low-toxicity azide reactive probe (NIR fluorescent dye), for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO hexafluorophosphate has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO hexafluorophosphate can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .

HY-W250928D

Biotin-PEG3400-azide		Azide
Biotin-PEG3400-azide is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; azide, is a moderately good leaving group, can react with alkyne by Cu-catalyzation, which improve the efficiency of biotin binding targets. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-W250928C

Biotin-PEG2000-azide		Azide
Biotin-PEG2000-azide is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; azide, is a moderately good leaving group, can react with alkyne by Cu-catalyzation, which improve the efficiency of biotin binding targets. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-W704973

F-ara-EdU		Alkynes
F-ara-EdU is a low-toxic, highly stable probe for DNA synthesis that is used as a marker for cell proliferation and DNA replication by binding to DNA or RNA in cells. F-ara-EdU can also be used to detect the rate of DNA synthesis within cells, as well as to study the mechanisms of DNA repair and damage .

HY-178925

PROTAC GPX4 degrader-5		Alkynes
PROTAC GPX4 degrader-5 (compound N15) is an efficient and highly selective PROTAC GPX4 degrader (DC₅₀ = 28 nM). PROTAC GPX4 degrader-5 can induce ferroptosis and has low toxicity to normal cells. PROTAC GPX4 degrader-5 can significantly increase ROS. PROTAC GPX4 degrader-5 exerts anti proliferative effects on various tumor cells. PROTAC GPX4 degrader-5 is commonly used in cancer research .

HY-146691

hMAO-B-IN-2		Alkynes
hMAO-B-IN-2 (compound 6j) is an orally active, potent, selective and BBB penetrated and competitive reversible hMAO-B inhibitor, with an IC₅₀ of 4 nM. hMAO-B-IN-2 shows low toxicity and good neuroprotective effects in SH-SY5Y cell. hMAO-B-IN-2 can be used for alzheimer’s disease research . hMAO-B-IN-2 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-147206C

Biotin-PEG3400-Alk		Alkynes
Biotin-PEG3400-Alk is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG3400-Alk is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-147206A

Biotin-PEG1000-Alk		Alkynes
Biotin-PEG1000-Alk is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG1000-Alk is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-147206E

Biotin-PEG10000-Alk		Alkynes
Biotin-PEG10000-Alk is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG10000-Alk is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-147206B

Biotin-PEG2000-Alk		Alkynes
Biotin-PEG2000-Alk is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG2000-Alk is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-147206F

Biotin-PEG20000-Alk		Alkynes
Biotin-PEG20000-Alk is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG20000-Alk is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-B2247A

PLGA (75:25) 5+ Cited Publications poly(lactic-co-glycolic acid) (75:25)		Polymers
PLGA (75:25) is a low toxicity, biocompatible and biodegradable controlled drug delivery carrier, can achieve slow release in the organism. PLGA (75:25) is a copolymer of 75% poly lactic acid (PLA) and 25% poly glycolic acid (PGA). PLGA (75:25) has been extensively studied as delivery vehicles for agents, proteins and various other macromolecules such as DNA, RNA and peptides .

HY-13859

Clevudine 1 Publications Verification L-FMAU		Nucleoside Analogs Thymidine
Clevudine (L-FMAU), a nucleoside analog of the unnatural L-configuration, has potent anti-HBV activity with long half-life, low toxicity. Clevudine is a non-competitive inhibitor that is not incorporated into the viral DNA but rather binds to the polymerase. Clevudine is active against cowpox virus respiratory infection in mice .

HY-160062

S2.2 aptamer sodium		Aptamers
S2.2 aptamer sodium is a nucleic acid-based MUC1-binding aptamer with high affinity and low toxicity. Upon binding to its target, S2.2 aptamer sodium undergoes a conformational switch and restores fluorescence signal, serving as a targeted imaging agent for MUC1-positive cancer cells. S2.2 aptamer sodium enables targeted delivery to breast cancer cells with overexpressed MUC1. When formulated as the S2.2-PEG-MZF molecular probe, S2.2 aptamer sodium possesses the functions of T2 signal inhibition, magnetic field-induced hyperthermia and targeted magnetic resonance molecular imaging. In the S2.2-PEG-MZF/DOX nanoliposome, S2.2 aptamer sodium supports targeted thermochemotherapy, effectively inhibiting cancer cell proliferation and invasion as well as inducing apoptosis, and is widely used in studies related to breast cancer .

HY-166997

AL-A12		Cationic Lipids
AL-A12 is a short-chain amino lipid with high gene delivery efficiency and low toxicity, and can be used in drug delivery research .

HY-147207C

Phospholipid-PEG5000-Biotin		Pegylated Lipids
Phospholipid-PEG5000-Biotin is a phospholipid PEG derivative, can be used for modify liposome and cells surface, and pancreatic islets for cell transplantation. Phospholipid is a class of lipid containing a hydrophilic “head” and two hydrophobic “tails”; PEG is a hydrophilic and water-soluble polymer with low toxicity; Biotin is an enzyme co-factor, can be used for labeling protein .

HY-147207A

Phospholipid-PEG2000-Biotin		Pegylated Lipids
Phospholipid-PEG2000-Biotin is a Biotin labeled phospholipid PEG derivative, can be used for modify liposome and cells surface, and pancreatic islets for cell transplantation. Phospholipid is a class of lipid containing a hydrophilic "head" and two hydrophobic "tails" ; PEG is a hydrophilic and water-soluble polymer with low toxicity; Biotin is an enzyme co-factor, can be used for labeling protein .

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