PROTAC CDK4/6/9 degrader 2
PROTAC CDK4/6/9 degrader 2 (Compound P4) is a CDK4/6/9 PROTAC prodrug with oral activity and low toxicity. PROTAC CDK4/6/9 degrader 2 can significantly inhibit tumor growth and suppress tumor lung metastasis. PROTAC CDK4/6/9 degrader 2 can be used in the research of cancer such as breast cancer. (Pink: CDK4/6/9 Ligand (HY-168440); Blue: CRBN Ligand (HY-178517); Black: Linker (HY-178512))
(Pink: CDK4 and CDK6 ligand (HY-168440); Blue: Cereblon ligand (HY-178517); Black: linker (HY-178512)).
For research use only. We do not sell to patients.
- Formula: C64H86N12O9
- Molecular Weight:1167.44
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All PROTACs Isoforms
More
Biological Activity
|
CDK4 |
CDK6 |
CDK9 |
Chemical Information
-
Molecular Weight 1167.44
-
Formula C64H86N12O9
-
SMILES
O=C(N(C)C)C1=CC2=CN=C(N=C2N1C3CCCC3)NC4=CC=C(C=C4)C(CN5CCN(CC5)CC6CCN(CC6)CC(N7CCN(CC7)C8=CC9=C(C=C8)C(N(C9=O)C(C(N%10COC(CCCCCCCCCCC)=O)=O)CCC%10=O)=O)=O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)