THAM maleate
Based on 1 publication(s) in Google Scholar
THAM (Tris) maleate is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. THAM maleate is an effective amine compound for pH control in the physiological range.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 72200-76-1
- Formula: C8H15NO7
- Molecular Weight:237.21
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) THAM maleate
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Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 72200-76-1
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Appearance Solid
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Molecular Weight 237.21
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Formula C8H15NO7
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Color White to off-white
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SMILES
OCC(CO)(N)CO.OC(/C=C\C(O)=O)=O
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Synonyms
Tris maleate; Tris(hydroxymethyl)aminomethane maleate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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ACS Omega
Highly Efficient Photoelectrochemical Detection of Cystatin C Based on a Core-Shell MOF Nanocomposite with Biomimetic-Catalysis Amplification. [Abstract]2024 Jun 14;9(26):28228-28236. PMID: 38973831
Solvent & Solubility
H2O : ≥ 100 mg/mL (421.57 mM)
DMSO : 87.5 mg/mL (368.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Nahas GG, et al. Guidelines for the treatment of acidaemia with THAM. Drugs. 1998 Feb;55(2):191-224. [Content Brief]
[2]. Höstman S, et al. THAM reduces CO2-associated increase in pulmonary vascular resistance - an experimental study in lung-injured piglets. Crit Care. 2015 Sep 17;19(1):331. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 4.2157 mL | 21.0784 mL | 42.1567 mL | 105.3918 mL |
| 5 mM | 0.8431 mL | 4.2157 mL | 8.4313 mL | 21.0784 mL | |
| 10 mM | 0.4216 mL | 2.1078 mL | 4.2157 mL | 10.5392 mL | |
| 15 mM | 0.2810 mL | 1.4052 mL | 2.8104 mL | 7.0261 mL | |
| 20 mM | 0.2108 mL | 1.0539 mL | 2.1078 mL | 5.2696 mL | |
| 25 mM | 0.1686 mL | 0.8431 mL | 1.6863 mL | 4.2157 mL | |
| 30 mM | 0.1405 mL | 0.7026 mL | 1.4052 mL | 3.5131 mL | |
| 40 mM | 0.1054 mL | 0.5270 mL | 1.0539 mL | 2.6348 mL | |
| 50 mM | 0.0843 mL | 0.4216 mL | 0.8431 mL | 2.1078 mL | |
| 60 mM | 0.0703 mL | 0.3513 mL | 0.7026 mL | 1.7565 mL | |
| 80 mM | 0.0527 mL | 0.2635 mL | 0.5270 mL | 1.3174 mL | |
| 100 mM | 0.0422 mL | 0.2108 mL | 0.4216 mL | 1.0539 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
THAM maleate Related Classifications
HY-W393372 Related Classifications
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