1. Anti-infection
  2. HBV

Clevudine 

Cat. No.: HY-13859 Purity: >98.0%
Data Sheet SDS Handling Instructions

Clevudine is an antiviral drug for the treatment of hepatitis B.

For research use only. We do not sell to patients.
Clevudine Chemical Structure

Clevudine Chemical Structure

CAS No. : 163252-36-6

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 296 In-stock
10 mg USD 269 In-stock
50 mg USD 815 In-stock
100 mg   Get quote  
200 mg   Get quote  

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  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Clevudine is an antiviral drug for the treatment of hepatitis B. Target: HBV Clevudine is a nucleoside analog with an unnatural beta-L configuration. Clevudine showed potent antiviral activity during therapy and induced a sustained posttreatment antiviral effect for 6 months after a 12-week treatment period, and this was associated with a sustained normalization of ALT levels [1]. Clevudine showed a potent antiviral response, and its effect was higher in HBeAg-negative patients, with rapid viral load reduction after therapy. However, long-term therapy for more than 1 year resulted in the development of considerable resistance and myopathy. Therefore, we should consider alternative antiviral agents if clevudine resistance or clevudine-induced myopathy is developed in patients on clevudine for the treatment of CHB [2].

Clinical Trial
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References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 3.8429 mL 19.2145 mL 38.4290 mL
5 mM 0.7686 mL 3.8429 mL 7.6858 mL
10 mM 0.3843 mL 1.9215 mL 3.8429 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

260.22

Formula

C₁₀H₁₃FN₂O₅

CAS No.

163252-36-6

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 50 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
Clevudine
Cat. No.:
HY-13859
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