1. Anti-infection
  2. HBV

Clevudine 

Cat. No.: HY-13859 Purity: >98.0%
Handling Instructions

Clevudine is an antiviral drug for the treatment of hepatitis B.

For research use only. We do not sell to patients.

Clevudine Chemical Structure

Clevudine Chemical Structure

CAS No. : 163252-36-6

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 296 In-stock
Estimated Time of Arrival: December 31
10 mg USD 269 In-stock
Estimated Time of Arrival: December 31
50 mg USD 815 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Clevudine is an antiviral drug for the treatment of hepatitis B. Target: HBV Clevudine is a nucleoside analog with an unnatural beta-L configuration. Clevudine showed potent antiviral activity during therapy and induced a sustained posttreatment antiviral effect for 6 months after a 12-week treatment period, and this was associated with a sustained normalization of ALT levels [1]. Clevudine showed a potent antiviral response, and its effect was higher in HBeAg-negative patients, with rapid viral load reduction after therapy. However, long-term therapy for more than 1 year resulted in the development of considerable resistance and myopathy. Therefore, we should consider alternative antiviral agents if clevudine resistance or clevudine-induced myopathy is developed in patients on clevudine for the treatment of CHB [2].

Clinical Trial
Solvent & Solubility
In Vitro: 

DMSO : ≥ 50 mg/mL (192.15 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8429 mL 19.2145 mL 38.4290 mL
5 mM 0.7686 mL 3.8429 mL 7.6858 mL
10 mM 0.3843 mL 1.9215 mL 3.8429 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

260.22

Formula

C₁₀H₁₃FN₂O₅

CAS No.

163252-36-6

SMILES

O=C(C(C)=CN1[[email protected]]2O[[email protected]@H](CO)[[email protected]](O)[[email protected]]2F)NC1=O

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Clevudine
Cat. No.:
HY-13859
Quantity:

Clevudine

Cat. No.: HY-13859