COX-1/2-IN-3
COX-1/2-IN-3 (Compound 7a) is a COX-1 and COX-2 inhibitor. COX-2-IN-15 shows anti-inflammatory activity with low toxicity.
For research use only. We do not sell to patients.
- CAS No.: 2428387-82-8
- Formula: C14H8N2O8
- Molecular Weight:332.22
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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COX-1 |
COX-2 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| J774.A1 | CC50 |
387.67 μM
Compound: 7a
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Cytotoxicity against mouse J774A1 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
Cytotoxicity against mouse J774A1 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
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[PMID: 32503692] |
| L929 | CC50 |
439.39 μM
Compound: 7a
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Cytotoxicity against mouse L929 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against mouse L929 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
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[PMID: 32503692] |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2428387-82-8
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Molecular Weight 332.22
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Formula C14H8N2O8
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SMILES
O=C1NC(C(O)=O)=C(C(C2=CC=C(C=C2)[N+]([O-])=O)=O)C=C1C(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
COX-1/2-IN-3 Related Classifications
HY-147693 Related Classifications
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