2. Immunology/Inflammation
  3. COX
  4. COX-1/2-IN-3

COX-1/2-IN-3 (Compound 7a) is a COX-1 and COX-2 inhibitor. COX-2-IN-15 shows anti-inflammatory activity with low toxicity.

For research use only. We do not sell to patients.

COX-1/2-IN-3 Chemical Structure

COX-1/2-IN-3 Chemical Structure

CAS No. : 2428387-82-8

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COX-1/2-IN-3 Related Antibodies

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Description

COX-1/2-IN-3 (Compound 7a) is a COX-1 and COX-2 inhibitor. COX-2-IN-15 shows anti-inflammatory activity with low toxicity[1].

IC50 & Target

COX-1

 

COX-2

 

In Vivo

COX-1/2-IN-3 (Compound 7a) (1.25 and 0.625 mg/ear) exhibits a high level of in vivo anti-inflammatory activity, reducing ear edema and myeloperoxidase (MPO) activity[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

332.22

Formula

C14H8N2O8
CAS No.
SMILES

O=C1NC(C(O)=O)=C(C(C2=CC=C(C=C2)[N+]([O-])=O)=O)C=C1C(O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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COX-1/2-IN-3 Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

COX-1/2-IN-32428387-82-8COXCyclooxygenaseanti-inflammatorylow toxicitymyeloperoxidaseear edemaInhibitorinhibitorinhibit

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