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Cat. No.: HY-178482

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HDZI 2,4OH

HDZI 2,4OH exerts significant anti anxiety activity through GABA receptors. HDZI 2,4OH can penetrate the blood-brain barrier. HDZI 2,4OH exhibits low toxicity in zebrafish. HDZI 2,4OH can be used for research on neurological disorders such as anxiety disorders.

For research use only. We do not sell to patients.

CAS No.: 263153-49-7
Formula: C₁₃H₁₁N₃O₃
Molecular Weight:257.24

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

HDZI 2,4OH Chemical Structure

CAS No.: 263153-49-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	EC₅₀	4 μM Compound: 4	Cytotoxicity against human HCT116 p53 +/+ and -/- cells after 72 hrs by MTT assay Cytotoxicity against human HCT116 p53 +/+ and -/- cells after 72 hrs by MTT assay	[PMID: 23306052]

Chemical Information

CAS No. 263153-49-7
Molecular Weight 257.24
Formula C₁₃H₁₁N₃O₃
SMILES

O=C(N/N=C/C1=CC=C(O)C=C1O)C2=CC=NC=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Maria Barros Alves A, et al. Synthesis, Characterization, and Evaluation of the Anxiolytic Activity of Hydrazones Derived from the Drug Isoniazid, Using the Adult Zebrafish (Danio rerio) Model. ACS Omega. 2025 Sep 25;10(39):45152-45164. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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