1. Anti-infection
  2. Antibiotic Bacterial
  3. Carbenicillin disodium

Carbenicillin disodium  (Synonyms: Sodium carbenicillin)

Cat. No.: HY-B0525A Purity: 99.14%
COA Handling Instructions

Carbenicillin disodium (Sodium carbenicillin) is a broad-spectrum semi-synthetic penicillin antibiotic for gram-negative bacteria. Carbenicillin disodium can interfere the cell wall synthesis while displaying low toxicity to plant tissue.

For research use only. We do not sell to patients.

Carbenicillin disodium Chemical Structure

Carbenicillin disodium Chemical Structure

CAS No. : 4800-94-6

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Customer Review

Based on 4 publication(s) in Google Scholar

Other Forms of Carbenicillin disodium:

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Description

Carbenicillin disodium (Sodium carbenicillin) is a broad-spectrum semi-synthetic penicillin antibiotic for gram-negative bacteria. Carbenicillin disodium can interfere the cell wall synthesis while displaying low toxicity to plant tissue[1].

IC50 & Target

β-lactam

 

In Vivo

Carbenicillin (100-400 mg/kg; intramuscular injection every 8 h for 72 h) disodium significantly reduces mortality of neutropenic Pseudomonas-infected rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

422.36

Formula

C17H16N2Na2O6S

CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC(C(C(O[Na])=O)C3=CC=CC=C3)=O)N1C2=O)O[Na]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (295.96 mM; Need ultrasonic)

DMSO : 62.5 mg/mL (147.98 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3676 mL 11.8382 mL 23.6765 mL
5 mM 0.4735 mL 2.3676 mL 4.7353 mL
10 mM 0.2368 mL 1.1838 mL 2.3676 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (236.76 mM); Clear solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.08 mg/mL (4.92 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.08 mg/mL (4.92 mM); Clear solution

  • 4.

    Add each solvent one by one:  10% DMSO    90% Corn Oil

    Solubility: ≥ 2.08 mg/mL (4.92 mM); Clear solution

*All of the co-solvents are available by MedChemExpress (MCE).
Purity & Documentation

Purity: 99.14%

References
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Carbenicillin disodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Carbenicillin disodium
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HY-B0525A
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