1. GPCR/G Protein
    Metabolic Enzyme/Protease
  2. Prostaglandin Receptor
    Phospholipase
  3. 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide

2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide 

Cat. No.: HY-100287
Handling Instructions

2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide is a compound that inhibits stress-induced ulcer and low toxicity, and can maintain the content of phospholipase A2 and prostaglandin E2 in ulcerated rats induced by water immersed restrained stress.

For research use only. We do not sell to patients.

2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide Chemical Structure

2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide Chemical Structure

CAS No. : 137089-36-2

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Description

2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide is a compound that inhibits stress-induced ulcer and low toxicity, and can maintain the content of phospholipase A2 and prostaglandin E2 in ulcerated rats induced by water immersed restrained stress.

IC50 & Target[1]

PGE2

 

PGI2

 

PLA2

 

In Vivo

2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (compd.III-1α, 100 mg/kg, p.o.) maintains the relative content of Fr.I hexose, lipid peroxide and phospholipase A2 (PLA2) in normal level in ulcerated rats induced by water immersed restrained stress via dosing twice a day for 3 day (b.i.d. for 3 d). 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (100 mg/kg, p.o.) reduces the hexosamine content equally with the control group 4 h after the stress loading, and then markedly increases 7 h after stress loading. 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (25 mg/kg, p.o.) blocks the reduction of prostaglandin E2 (PGE2) and PGI2 in early phase and accelerates the increase of PGE2 and PGI2 in the late phase of the stress. 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (25 mg/kg, p.o.) also significantly accelerates the cell proliferation in fundic glands in gastric mucosa of mice[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

339.58

Formula

C₂₀H₃₇NOS

CAS No.

137089-36-2

SMILES

CCCCCCC/C=C/C(NCCSCCC1CCCCC1)=O

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Room temperature in continental US; may vary elsewhere

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Product Name:
2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide
Cat. No.:
HY-100287
Quantity:

2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide

Cat. No.: HY-100287