2. Anti-infection
  3. Fungal
  4. Antifungal agent 51

Antifungal agent 51 (Compound 5c) has potent antifungal activity, especially against Candida albicans FDC 151 , Candida parapsilosis ATCC 22019 and Candida tropicalis FDC 138, with the MIC value is less than 0.063 μg/mL, and it has low toxicity to cells and no carcinogenicity.

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Antifungal agent 51 Chemical Structure

Antifungal agent 51 Chemical Structure

CAS No. : 2896209-47-3

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Antifungal agent 51 Related Antibodies

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Description

Antifungal agent 51 (Compound 5c) has potent antifungal activity, especially against Candida albicans FDC 151 , Candida parapsilosis ATCC 22019 and Candida tropicalis FDC 138, with the MIC value is less than 0.063 μg/mL, and it has low toxicity to cells and no carcinogenicity[1].

In Vitro

Antifungal agent 51 has potent antifungal activity, especially against Candida albicans FDC 151, Candida parapsilosis ATCC 22019 and Candida tropicalis FDC 138, with the MIC value is less than 0.063 μg/mL, and against Candida albicans CMRC 19 and Candida glabrata FDC 192 with MIC value of 0.125 μg/mL, against Candida albicans CMRC 192, with MIC value of 0.25 μg/mL, against Candida glabrata CMRC 89, with MIC value of 1 μg/mL[1].
Antifungal agent 51 (6.25, 12.5, 25 μg/mL; 48 h) partially affects the viability of cell lines even at relatively high concentration of 25 μg/mL in BEAS-2B and HepG2 cells [1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antifungal agent 51 Related Antibodies

Cell Viability Assay[1]

Cell Line: BEAS-2B and HepG2 cells
Concentration: 6.25, 12.5, and 25 μg/mL
Incubation Time: 48 h
Result: Partially affected the viability of cell lines even at relatively high concentration of 25 μg/mL in BEAS-2B and HepG2 cells
Molecular Weight

369.42

Formula

C18H16FN5OS
CAS No.
SMILES

FC1=CC=C(C(CSC2=NC3=C(N2)C=CC=C3)(CN4N=CN=C4)O)C=C1
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
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Antifungal agent 51 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antifungal agent 512896209-47-3Antifungal agent51Antifungal agent-51FungalAntifungalCandida albicans FDC 151 Candida parapsilosis ATCC 22019Candida tropicalis FDC 138Inhibitorinhibitorinhibit

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