Ferrocene
Based on 1 Customer Validation
Ferrocene is an organometallic compound. Ferrocene serves as an important structural core in bioorganometallic chemistry due to its inherent stability, excellent oxygen reduction performance, and low toxicity.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 102-54-5
- Formula: C10H10Fe
- Molecular Weight:186.03
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Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Ferrocene is referred to as a sandwich complex and is widely used in multiple fields including organometallic chemistry research, electrochemistry, catalysis, medicinal chemistry, and materials science. It can be used to design iron-containing drug molecules with anti-tumor and anti-malaria activities.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 102-54-5
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Appearance Solid
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Molecular Weight 186.03
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Formula C10H10Fe
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Color Light yellow to yellow
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SMILES
[][Fe][].c1cccc1.c2cccc2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 40 mg/mL (215.02 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 4 mg/mL (21.50 mM); Clear solution
This protocol yields a clear solution of ≥ 4 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (40.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (280 KB)
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SDS (915 KB)
- English - EN (915 KB)
- Français - FR (915 KB)
- Deutsch - DE (915 KB)
- Norwegian - NO (915 KB)
- Español - ES (915 KB)
- Swedish - SV (915 KB)
- Italian - IT (915 KB)
- Korean - KR (915 KB)
- Portuguese - PT (915 KB)
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Handling Instructions (2659 KB)
References
[1]. Rauf U, et al. Contemporary Developments in Ferrocene Chemistry: Physical, Chemical, Biological and Industrial Aspects. Molecules. 2023 Jul 30;28(15):5765. [Content Brief]
[2]. Sharma B, et al. Has Ferrocene Really Delivered Its Role in Accentuating the Bioactivity of Organic Scaffolds?. Journal of medicinal chemistry. 2021 Dec 09;64(23):16865-16921. [Content Brief]
[3]. van Staveren DR, Metzler-Nolte N. Bioorganometallic chemistry of ferrocene. Chem Rev. 2004 Dec;104(12):5931-85. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.3755 mL | 26.8774 mL | 53.7548 mL | 134.3869 mL |
| 5 mM | 1.0751 mL | 5.3755 mL | 10.7510 mL | 26.8774 mL | |
| 10 mM | 0.5375 mL | 2.6877 mL | 5.3755 mL | 13.4387 mL | |
| 15 mM | 0.3584 mL | 1.7918 mL | 3.5837 mL | 8.9591 mL | |
| 20 mM | 0.2688 mL | 1.3439 mL | 2.6877 mL | 6.7193 mL | |
| 25 mM | 0.2150 mL | 1.0751 mL | 2.1502 mL | 5.3755 mL | |
| 30 mM | 0.1792 mL | 0.8959 mL | 1.7918 mL | 4.4796 mL | |
| 40 mM | 0.1344 mL | 0.6719 mL | 1.3439 mL | 3.3597 mL | |
| 50 mM | 0.1075 mL | 0.5375 mL | 1.0751 mL | 2.6877 mL | |
| 60 mM | 0.0896 mL | 0.4480 mL | 0.8959 mL | 2.2398 mL | |
| 80 mM | 0.0672 mL | 0.3360 mL | 0.6719 mL | 1.6798 mL | |
| 100 mM | 0.0538 mL | 0.2688 mL | 0.5375 mL | 1.3439 mL |
Ferrocene Related Classifications
HY-79504 Related Classifications
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