Etimicin sulfate
Based on 1 Customer Validation
Etimicin (sulfate), a fourth-generation aminoglycoside antibiotic, is now widely clinically used due to its high efficacy and low toxicity.
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- Purity : 99.59%
- CAS No.: 362045-44-1
- 화학식: C21H43N5O7.xH2SO4
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Antibiotic Isoforms
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Biological Activity
제품 설명
IC50 & Target
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Aminoglycoside |
Chemical Information
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CAS No. 362045-44-1
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Appearance Solid
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화학식 C21H43N5O7.xH2SO4
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Color White to off-white
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SMILES
O=S(O)(O)=O.CCN[C@H](C[C@@H]([C@H]([C@@H]1O)O[C@H]2O[C@@H](CC[C@H]2N)CN)N)[C@@H]1O[C@@H]3[C@@H]([C@H]([C@@](O)(CO3)C)NC)O.[x]
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
용액&용해도
In Vitro:
H2O : 100 mg/mL (Need ultrasonic)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
순도&문서
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Yao L, Zhang JW, Chen B, et al. Mechanisms and pharmacokinetic/pharmacodynamic profiles underlying the low nephrotoxicity and ototoxicity of etimicin. Acta Pharmacol Sin. 2020;41(6):866-878. [Content Brief]
[2]. Shao W, Zhong D, Jiang H, et al. A new aminoglycoside etimicin shows low nephrotoxicity and ototoxicity in zebrafish embryos. J Appl Toxicol. 2021;41(7):1063-1075. [Content Brief]