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  4. BODIPY-TS

BODIPY-TS  (Synonyms: Thiol-green 2)

Cat. No.: HY-D1262 Purity: 97.22%
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BODIPY-TS (Thiol-green 2) is a fast response and thiol-specific turn-on probe. BODIPY-TS utilizes the thiosulfonate scaffold as a thiol recognition unit. BODIPY-TS has low toxicity, and features high selectivity, low detection limit, and quantitative reaction to thiols. Ex: 490 nM; Em: 515 nM.

For research use only. We do not sell to patients.

BODIPY-TS Chemical Structure

BODIPY-TS Chemical Structure

CAS No. : 1808174-52-8

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1 mg USD 350 In-stock
5 mg USD 770 In-stock
10 mg USD 1240 In-stock
25 mg USD 2480 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

BODIPY-TS (Thiol-green 2) is a fast response and thiol-specific turn-on probe. BODIPY-TS utilizes the thiosulfonate scaffold as a thiol recognition unit. BODIPY-TS has low toxicity, and features high selectivity, low detection limit, and quantitative reaction to thiols[1]. Ex: 490 nM; Em: 515 nM.

Molecular Weight

434.33

Formula

C20H21BF2N2O2S2
CAS No.
Appearance

Solid

Color

Orange to red

Emission (Em)

515
Excitation (Ex)

505
SMILES

CS(SC1=CC=C(C2=C3[N+]([B-](F)(F)N4C2=C(C)C=C4C)=C(C)C=C3C)C=C1)(=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (230.24 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3024 mL 11.5120 mL 23.0240 mL
5 mM 0.4605 mL 2.3024 mL 4.6048 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3024 mL 11.5120 mL 23.0240 mL 57.5599 mL
5 mM 0.4605 mL 2.3024 mL 4.6048 mL 11.5120 mL
10 mM 0.2302 mL 1.1512 mL 2.3024 mL 5.7560 mL
15 mM 0.1535 mL 0.7675 mL 1.5349 mL 3.8373 mL
20 mM 0.1151 mL 0.5756 mL 1.1512 mL 2.8780 mL
25 mM 0.0921 mL 0.4605 mL 0.9210 mL 2.3024 mL
30 mM 0.0767 mL 0.3837 mL 0.7675 mL 1.9187 mL
40 mM 0.0576 mL 0.2878 mL 0.5756 mL 1.4390 mL
50 mM 0.0460 mL 0.2302 mL 0.4605 mL 1.1512 mL
60 mM 0.0384 mL 0.1919 mL 0.3837 mL 0.9593 mL
80 mM 0.0288 mL 0.1439 mL 0.2878 mL 0.7195 mL
100 mM 0.0230 mL 0.1151 mL 0.2302 mL 0.5756 mL
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BODIPY-TS Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BODIPY-TS1808174-52-8Thiol-green 2Fluorescent Dyethiol-specificthiosulfonatelow detectionlow toxicityprobeInhibitorinhibitorinhibit

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