2. Metabolic Enzyme/Protease
  3. Pyruvate Kinase
  4. TEPC466

TEPC466 is a novel TEPP-46-based aggregation-induced emission (AIE) probe. TEPC466 shows a high degree of selectivity and sensitivity for the detection of PKM2 protein via the AIE effect. EPC466 can be used for the detection of PKM2. TEPC466 is successfully applied in imaging the PKM2 protein in colorectal cancer cells with low toxicity. TEPC466 is a useful tool for cancer diagnosis and research.

For research use only. We do not sell to patients.

TEPC466 Chemical Structure

TEPC466 Chemical Structure

CAS No. : 2621957-88-6

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Description

TEPC466 is a novel TEPP-46-based aggregation-induced emission (AIE) probe. TEPC466 shows a high degree of selectivity and sensitivity for the detection of PKM2 protein via the AIE effect. EPC466 can be used for the detection of PKM2. TEPC466 is successfully applied in imaging the PKM2 protein in colorectal cancer cells with low toxicity. TEPC466 is a useful tool for cancer diagnosis and research[1].

Molecular Weight

544.60

Formula

C27H20N4O5S2
CAS No.
Appearance

Solid

Color

Off-white to yellow

SMILES

O=C1N(N=CC2=C1N(C)C3=C2SC(S(C)=O)=C3)CC4=CC=CC(NC(C5=CC6=CC=CC=C6OC5=O)=O)=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
References
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TEPC466 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TEPC4662621957-88-6TEPC 466TEPC-466Pyruvate Kinaseaggregation-induced emissionAIEselectivitysensitivityPKM2 colorectal cancerlow toxicitycancer diagnosisInhibitorinhibitorinhibit

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