Antifungal agent 43
Antifungal agent 43 (compound B05) is an antifungal agent. Antifungal agents 43 has antifungal activity by inhibiting biofilm formation. Antifungal agent 43 has low toxicity in human cancer cell lines.
For research use only. We do not sell to patients.
- CAS No.: 3033703-29-3
- Formula: C24H26N4Se2
- Molecular Weight:528.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
14.74 μM
Compound: B05
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Cytotoxicity against human HL-60 cells by MTT assay
Cytotoxicity against human HL-60 cells by MTT assay
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[PMID: 36057236] |
| MDA-MB-231 | IC50 |
5.04 μM
Compound: B05
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Cytotoxicity against human MDA-MB-231 cells by MTT assay
Cytotoxicity against human MDA-MB-231 cells by MTT assay
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[PMID: 36057236] |
| PC-3 | IC50 |
7.43 μM
Compound: B05
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Cytotoxicity against human PC-3 cells by MTT assay
Cytotoxicity against human PC-3 cells by MTT assay
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[PMID: 36057236] |
Antifungal agent 43 (compound B05; 0.25-128 μg/mL) has antifungal activity against fungi strains with MIC values of 1, 1, 4, 4, 8, and 8 μg/mL for C.alb(sc5314), C.zey, C.alb, C.par, C.gla, and C.kru, respectively[1].
Antifungal agent 43 (0.25-128 μg/mL) has antifungal activity against azole-resistant strains with MIC values of 2, 4, 4, 4, and 32 μg/mL for strain CaR, strain 632, strain 901, strain 904, and strain 17#, respectively[1].
Antifungal agent 43 (0-10 μM) has low toxicity in human cancer cell lines with IC50 values of 5.04, 7.43 and 14.74 for MDA-MB-231, PC-3, and HL-60 cells, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3033703-29-3
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Molecular Weight 528.41
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Formula C24H26N4Se2
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SMILES
CC1=CC=C(C([Se][Se]C(C2=CC=C(C)C=C2)CN3C=CN=C3)CN4C=CN=C4)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antifungal agent 43 Related Classifications
HY-151442 Related Classifications
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