JAK/HDAC-IN-4
JAK/HDAC-IN-4 (compound 11 i) is a JAK/HDAC inhibitor with the IC50 values of 0.49 nM and 12 nM for JAK2 and HDAC6, respectively. JAK/HDAC-IN-4 inhibits the cell proliferation and the production of nitric oxide. JAK/HDAC-IN-4 ameliorates psoriasis-like skin lesions in an Imiquimod (HY-B0180)-induced murine model with low toxicity.
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- No. CAS: 3064994-08-4
- Fòrmula: C30H32N8O5S
- Peso molecular:616.69
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 3064994-08-4
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Peso molecular 616.69
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Fòrmula C30H32N8O5S
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SMILES
O=S(NC1=CC=C(C=C1)C2=NC(NC3=CC=C(C=C3)N4CCN(CC4)CC(NC5=CC=C(C=C5)C(NO)=O)=O)=NC=C2)(C)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
JAK/HDAC-IN-4 Related Classifications
HY-169290 Related Classifications
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