1. Signaling Pathways
  2. Membrane Transporter/Ion Channel
    Neuronal Signaling
  3. TRP Channel
  4. TRPV Isoform
  5. TRPV Antagonist

TRPV Antagonist

TRPV Antagonists (10):

Cat. No. Product Name Effect Purity
  • HY-12245
    SB-366791
    Antagonist 98.72%
    SB-366791 is a potent and selective vanilloid receptor (VR1/TRPV1) antagonist (IC50=5.7 nM).
  • HY-18662
    RQ-00203078
    Antagonist 99.84%
    RQ-00203078 is a highly selective, potent and orally active TRPM8 antagonist with IC50s of 5.3 nM and 8.3 nM for rat and human TRPM8 channels, respectively.
  • HY-100129
    JNJ-17203212
    Antagonist 99.94%
    JNJ-17203212 is a selective, potent and competitive TRPV1 antagonist.
  • HY-114017
    Vanilloid receptor antagonist 1
    Antagonist 98.07%
    Vanilloid receptor antagonist 1 is a potent vanilloid receptor TRPV1 antagonist extracted from patent US8349852B2, compound B8.
  • HY-19589
    JTS-653
    Antagonist
    JTS-653 is a highly potent and selective transient receptor potential vanilloid 1 (TRPV1) antagonist in vitro and in vivo.
  • HY-144372
    TRPV1 antagonist 3
    Antagonist
    TRPV1 antagonist 3 (Compound 7q) is a potent TRPV1 antagonist with an IC50 of 2.66 nM against capsaicin.
  • HY-P1175A
    L-R4W2 TFA
    Antagonist
    L-R4W2 TFA is a potent antagonist of vanilloid receptor 1 (VR1, TRPV1), with an IC50 of 0.1 μM.
  • HY-131868
    TRPV3 antagonist 74a
    Antagonist
    TRPV3 antagonist 74a is a potent and selective TRPV3 antagonist.
  • HY-P1175
    L-R4W2
    Antagonist
    L-R4W2 is a potent antagonist of vanilloid receptor 1 (VR1, TRPV1), with an IC50 of 0.1 μM.
  • HY-12914
    V116517
    Antagonist
    V116517 is a potent, orally active transient receptor potential vanilloid (TRPV1) antagonist.