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Cat. No.: HY-167160

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AZ12099548

AZ12099548 is a TRPV1 antagonist. AZ12099548 inhibits both Capsaicin (HY-10448)- and low pH-induced calcium mobilization.

For research use only. We do not sell to patients.

CAS No.: 790689-76-8
Formula: C₁₉H₂₀N₂O₃S
Molecular Weight:356.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

AZ12099548 Chemical Structure

CAS No.: 790689-76-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Bioz

Biological Activity

Description

AZ12099548 is a TRPV1 antagonist. AZ12099548 inhibits both Capsaicin (HY-10448)- and low pH-induced calcium mobilization^[1].

IC₅₀ & Target^[1]

hTRPV1

All TRP Channel Isoforms :

In Vitro

AZ12099548 (Compound AZ C) inhibits both Capsaicin (HY-10448)- and low pH-induced calcium mobilization in human TRPV1-expressing cells, with IC₅₀ values of 10 nM and 22 nM, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 790689-76-8
Molecular Weight 356.44
Formula C₁₉H₂₀N₂O₃S
SMILES

O=C(NC=1C=CC=2SC(=NC2C1)CO)C3=CC=C(OC(C)(C)C)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Cuypers E, et al. Transient receptor potential vanilloid 1 and xenobiotics. CNS Neurol Disord Drug Targets. 2008;7(2):159-171. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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AZ12099548

All TRP Channel Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

AZ12099548 Related Classifications

HY-167160 Related Classifications