2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. TRP Channel
  4. AZ12099548

AZ12099548 is a TRPV1 antagonist. AZ12099548 inhibits both Capsaicin (HY-10448)- and low pH-induced calcium mobilization.

For research use only. We do not sell to patients.

AZ12099548

AZ12099548 Chemical Structure

CAS No. : 790689-76-8

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AZ12099548 Related Antibodies

Top Publications Citing Use of Products

View All TRP Channel Isoform Specific Products:

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TRPA1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TRPM8 TRPM2 TRPM3 TRPM4 TRPM7 TRPML1 TRPML2 TRPML3 TRPV1 TRPV2 TRPV3 TRPV4 TRPV6

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Description

AZ12099548 is a TRPV1 antagonist. AZ12099548 inhibits both Capsaicin (HY-10448)- and low pH-induced calcium mobilization[1].

IC50 & Target[1]

hTRPV1

 

In Vitro

AZ12099548 (Compound AZ C) inhibits both Capsaicin (HY-10448)- and low pH-induced calcium mobilization in human TRPV1-expressing cells, with IC50 values of 10 nM and 22 nM, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

AZ12099548 Related Antibodies
Molecular Weight

356.44

Formula

C19H20N2O3S
CAS No.
SMILES

O=C(NC=1C=CC=2SC(=NC2C1)CO)C3=CC=C(OC(C)(C)C)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AZ12099548 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AZ12099548790689-76-8AZ 12099548AZ-12099548TRP ChannelTransient receptor potential channelscalcium mobilizationhVR1capsaicinTRPV1 antagonisthuman TRPV1-expressing cellsInhibitorinhibitorinhibit

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HY-167160
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