1. Membrane Transporter/Ion Channel
  2. TRP Channel
  3. Camphor

Camphor (Synonyms: (±)-Camphor)

Cat. No.: HY-N0808 Purity: >98.0%
Handling Instructions

Camphor ((±)-Camphor) is a topical anti-infective and anti-pruritic and internally as a stimulant and carminative. However, Camphor is poisonous when ingested. Antiviral, antitussive, and anticancer activities. Camphor is a TRPV3 agonist.

For research use only. We do not sell to patients.

Camphor Chemical Structure

Camphor Chemical Structure

CAS No. : 76-22-2

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Estimated Time of Arrival: December 31
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Description

Camphor ((±)-Camphor) is a topical anti-infective and anti-pruritic and internally as a stimulant and carminative. However, Camphor is poisonous when ingested. Antiviral, antitussive, and anticancer activities[1]. Camphor is a TRPV3 agonist[2].

IC50 & Target

TRPV3[2]

In Vitro

Camphor induces fibroblast proliferation through the PI3K/AKT and ERK signaling pathways[3].
The MTT assay results show that 32.5, 65, 130, and 260 μM Camphor increase fibroblast viability to 108.9±6.6%, 118.6±2.8%, 127.7±4.2%, and 131.6±7.2%, respectively, compared to 0 μM Camphor treatment[3].
Camphor (0-260 μM) treatment for 24 hours increases the generation of ROS by up to 17.97% compared to 5.04% in the no-treatment control[3]. Camphor (0-260 μM, 24 hours) induces the phosphorylation of PI3K, AKT, ERK, and 4EBP1 in a dose- and time-dependent manner[3].

Cell Viability Assay[3]

Cell Line: Primary dermal fibroblast cells
Concentration: 0-260 μM
Incubation Time: 24 hours
Result: 32.5, 65, 130, and 260 μM increased fibroblast viability to 108.9±6.6%, 118.6±2.8%, 127.7±4.2%, and 131.6±7.2%, respectively, compared to 0 μM treatment.

Western Blot Analysis[3]

Cell Line: Primary dermal fibroblast cells
Concentration: 0-260 μM
Incubation Time: 24 hours
Result: Induced the phosphorylation of PI3K, AKT, ERK, and 4EBP1, a repressor of mRNA translation and mTOR substrate, in a dose- and time-dependent manner.
Storage
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
References
Molecular Weight

152.23

Formula

C₁₀H₁₆O

CAS No.

76-22-2

SMILES

O=C1C(C2(C)C)(C)CCC2C1

Shipping

Room temperature in continental US; may vary elsewhere

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Camphor
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Camphor

Cat. No.: HY-N0808