1. Membrane Transporter/Ion Channel
  2. TRP Channel
  3. RN-1747

RN-1747 

Cat. No.: HY-19976
Handling Instructions

RN-1747 is a selective transient receptor potential cation channel subfamily V member 4 (TRPV4) agonist, with EC50 values are 0.77 μM, 4.0 μM and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4 respectively. RN-1747 also antagonizes TRPM8, with an IC50 of 4 μM.

For research use only. We do not sell to patients.

RN-1747 Chemical Structure

RN-1747 Chemical Structure

CAS No. : 1024448-59-6

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Description

RN-1747 is a selective transient receptor potential cation channel subfamily V member 4 (TRPV4) agonist, with EC50 values are 0.77 μM, 4.0 μM and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4 respectively. RN-1747 also antagonizes TRPM8, with an IC50 of 4 μM[1].

IC50 & Target

EC50: 0.77 μM (hTRPV4), 4.0 μM (mTRPV4), 4.1 μM (rTRPV4) [1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

395.86

Formula

C₁₇H₁₈ClN₃O₄S

CAS No.

1024448-59-6

SMILES

O=S(N1CCN(CC2=CC=CC=C2)CC1)(C3=CC=C(Cl)C=C3[N+]([O-])=O)=O

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
RN-1747
Cat. No.:
HY-19976
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RN-1747

Cat. No.: HY-19976