HC-067047 (Standard)
HC-067047 (Standard) is the analytical standard of HC-067047 (HY-100208). This product is intended for research and analytical applications. HC-067047 is a potent and selective TRPV4 antagonist and reversibly inhibits currents through the human, rat, and mouse TRPV4 orthologs with IC50 values of 48 nM, 133 nM, and 17 nM, respectively.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 98%
- CAS No.: 883031-03-6
- 화학식: C26H28F3N3O2
- 분자량:471.51
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- 순도&문서
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Help & FAQs
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HY-100208
HC-067047TRPV4 Antagonist -
HY-12245
SB-366791VR1/TRPV1 Antagonist -
HY-101736
AMG9810TRPV1 Antagonist -
HY-108463
A-967079TRPA1 Receptor Antagonist -
HY-19960
BCTCTRPV1/TRPM8 Antagonist -
HY-19975
RN-1734TRP Channel Antagonist -
HY-101840
EIPATRPP3 Channel Inhibitor -
HY-15064
HC-030031TRP Channel Inhibitor -
HY-100720
GSK2193874TRPV4 Antagonist -
HY-11062
IcilinTRPM8 Agonist -
HY-100001
SKF-96365 (hydrochloride)TRPC Channel Antagonist, SOCE Inhibitor -
HY-108449
AcoltremonTRPM8 agonist
Product Information
Information
신청
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 883031-03-6
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분자량 471.51
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화학식 C26H28F3N3O2
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SMILES
O=C(C1=C(C)N(CCCN2CCOCC2)C(C3=CC=CC=C3)=C1)NC4=CC=CC(C(F)(F)F)=C4
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Everaerts W et al. Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis.Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):19084-9. [Content Brief]
[2]. Xing Y, et al. Decreased Expression of TRPV4 Channels in HEI-OC1 Cells Induced by High Glucose Is Associated with Hearing Impairment. Yonsei Med J. 2018 Nov;59(9):1131-1137. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HC-067047 (Standard) Related Classifications
HY-100208R Related Classifications
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