JNJ-38893777
JNJ-38893777 is an orally active and highly selective transient receptor potential vanilloid type 1 (TRPV1) channel antagonist. JNJ-38893777 inhibits neuronal hyperactivation and reduces inflammatory hyperalgesia. JNJ-38893777 is promising for research of migraine headaches, neuropathic and inflammatory pain.
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- No. CAS: 951135-00-5
- Fòrmula: C26H26F6N6
- Peso molecular:536.52
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 951135-00-5
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Peso molecular 536.52
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Fòrmula C26H26F6N6
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SMILES
FC(C1=CC=CN=C1N2CCC3=NC(N4CCCCC4)=NC(NC5=CC=C(C(F)(F)F)C=C5)=C3CC2)(F)F
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Manitpisitkul P, et al. Safety, Tolerability and Pharmacokinetic and Pharmacodynamic Learnings from a Double-Blind, Randomized, Placebo-Controlled, Sequential Group First-in-Human Study of the TRPV1 Antagonist, JNJ-38893777, in Healthy Men. Clin Drug Investig. 2015 Jun;35(6):353-63. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
JNJ-38893777 Related Classifications
HY-119121 Related Classifications
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