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Referencia número: HY-142620

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TRPV4 antagonist 3

TRPV4 antagonist 3 is a TRPV4 antagonist (pIC₅₀ = 8.4).

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No. CAS: 2681273-35-6
Fòrmula: C₂₀H₁₈F₄N₄O₃S
Peso molecular:470.44

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

TRPV4 antagonist 3 Chemical Structure

No. CAS: 2681273-35-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- IC₅₀ & Target
Chemical Information
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Actividad biológica

Descripciòn

TRPV4 antagonist 3 is a TRPV4 antagonist (pIC₅₀ = 8.4).

IC₅₀ & Target

TRPV4

Ver todos los productos específicos de isoformas TRP Channel :

Chemical Information

No. CAS 2681273-35-6
Peso molecular 470.44
Fòrmula C₂₀H₁₈F₄N₄O₃S
SMILES

O=S(C1=CC=C(C#N)C=C1C(F)(F)F)(NCC[C@](C)(N)COC2=CC=C(C#N)C(F)=C2)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Patterson JR, et al. Design and Optimization of an Acyclic Amine Series of TRPV4 Antagonists by Electronic Modulation of Hydrogen Bond Interactions. J Med Chem. 2020 Dec 10;63(23):14867-14884. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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TRPV4 antagonist 3

Ver todos los productos específicos de isoformas TRP Channel