N-Linolenoylethanolamine (Synonyms: 18:3 NAE; α-Linolenoyl ethanolamide)

Cat. No.: HY-W747573: Data Sheet
COA

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Handling Instructions
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N-Linolenoylethanolamine (18:3 NAE) is an endocannabinoid. N-Linolenoylethanolamine is a vanillin receptor (TRPV1) agonist.

For research use only. We do not sell to patients.

N-Linolenoylethanolamine Chemical Structure

CAS No. : 57086-93-8

Size	Price	Stock	Quantity
Solvent
5 mg (155.52 mM * 100 μL in Ethanol)		Get quote 2 - 3 weeks 4 - 5 weeks 5 - 6 weeks 1 - 2 weeks	Estimated Time of Arrival: December 31

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Other Forms of N-Linolenoylethanolamine:

N-Linolenoylethanolamine-d₄ Get quote

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•Related Small Molecules:

•Related Proteins:

View All TRP Channel Isoform Specific Products:

View All Isoforms

TRPA1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TRPM8 TRPM2 TRPM3 TRPM4 TRPM7 TRPML1 TRPML2 TRPML3 TRPV1 TRPV2 TRPV3 TRPV4 TRPV6

Biological Activity
Purity & Documentation
References
Customer Review

Description

N-Linolenoylethanolamine (18:3 NAE) is an endocannabinoid. N-Linolenoylethanolamine is a vanillin receptor (TRPV1) agonist^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
RBL-2H3	IC₅₀	29 μM Compound: 12	Antiallergic activity in rat RBL2H3 cells assessed as inhibition of DNP-HSA-mediated degranulation by measuring decrease in beta-hexosaminidase activity preincubated for 30 mins followed by DNP-HSA stimulation and measured after 30 mins by 4-nitrophenyl 2-acetamido-2-deoxy-beta-D-glucopyranoside substrate based assay Antiallergic activity in rat RBL2H3 cells assessed as inhibition of DNP-HSA-mediated degranulation by measuring decrease in beta-hexosaminidase activity preincubated for 30 mins followed by DNP-HSA stimulation and measured after 30 mins by 4-nitrophenyl 2-acetamido-2-deoxy-beta-D-glucopyranoside substrate based assay	[PMID: 31618024]

Molecular Weight

321.50

Formula

C₂₀H₃₅NO₂

CAS No.

57086-93-8

Appearance

Liquid

Color

Colorless to light yellow

SMILES

CC/C=C\C/C=C\C/C=C\CCCCCCCC(NCCO)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Solution, -20°C, 2 years

Purity & Documentation

Purity: 99.9%

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Data Sheet (260 KB) SDS (393 KB)

COA (237 KB)

Handling Instructions (2659 KB)

References

[1]. Movahed P, et al. Endogenous unsaturated C18 N-acylethanolamines are vanilloid receptor (TRPV1) agonists. J Biol Chem. 2005 Nov 18;280(46):38496-504. [Content Brief]

N-Linolenoylethanolamine Related Classifications

Neurological Disease

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Linolenoylethanolamine57086-93-818:3 NAE α-Linolenoyl ethanolamideTRP ChannelTransient receptor potential channelsα-Linolenoyl ethanolamideTRPV1AgonistInhibitorinhibitorinhibit

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