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Cat. No.: HY-108576

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Linopirdine dihydrochloride

(Synonyms: DuP 996 dihydrochloride)

2 Cited Publications

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Based on 2 publication(s) in Google Scholar

Linopirdine dihydrochloride is a agonist of capsaicin receptor TRPV1. Linopirdine increases the intracellular calcium concentration in HEK293 cells. Linopirdine dihydrochloride exerts an excitatory action on mammalian nociceptors.

For research use only. We do not sell to patients.

CAS No.: 113168-57-3
Formula: C₂₆H₂₃Cl₂N₃O
Molecular Weight:464.39

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Linopirdine dihydrochloride Chemical Structure

CAS No.: 113168-57-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All TRP Channel Isoforms :

Chemical Information

CAS No. 113168-57-3
Molecular Weight 464.39
Formula C₂₆H₂₃Cl₂N₃O
SMILES

O=C1N(C2=CC=CC=C2)C3=C(C=CC=C3)C1(CC4=CC=NC=C4)CC5=CC=NC=C5.Cl.Cl
Synonyms

DuP 996 dihydrochloride
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (2)

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Curr Biol

Venom resistance mechanisms in centipede show tissue specificity. [Abstract]

2022 Aug 22;32(16):3556-3563.e3. PMID: 35863353
Res Sq

2025 Nov 12.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Neacsu C, et al. The M-channel blocker linopirdine is an agonist of the capsaicin receptor TRPV1. J Pharmacol Sci. 2010;114(3):332-40. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Linopirdine dihydrochloride

2 Cited Publications

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Publications (2)
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Linopirdine dihydrochloride

Publications Citing Use of MedChemExpress (MCE) Linopirdine dihydrochloride

All TRP Channel Isoforms

Biological Activity

Chemical Information

Publications (2)

Purity & Documentation

References

Calculators

Help & FAQs

Linopirdine dihydrochloride Related Classifications

HY-108576 Related Classifications