113168-57-3
113168-57-3
Chemical Structure
Linopirdine dihydrochloride
Synonym(s): DuP 996 dihydrochloride
- CAS No.: 113168-57-3
- Formula:C26H23Cl2N3O
- Molecular Weight:464.39
IUPAC Name: 1-phenyl-3,3-bis(pyridin-4-ylmethyl)indolin-2-one dihydrochloride
InChIKey: ZEVVHCGTTNRYOY-UHFFFAOYSA-N
SMILES: O=C1N(C2=CC=CC=C2)C3=C(C=CC=C3)C1(CC4=CC=NC=C4)CC5=CC=NC=C5.Cl.Cl
Biological Activity: Linopirdine dihydrochloride is a agonist of capsaicin receptor TRPV1. Linopirdine increases the intracellular calcium concentration in HEK293 cells. Linopirdine dihydrochloride exerts an excitatory action on mammalian nociceptors[1].
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Linopirdine dihydrochloride | Linopirdine dihydrochloride is a agonist of capsaicin receptor TRPV1. Linopirdine increases the intracellular calcium concentration in HEK293 cells. Linopirdine dihydrochloride exerts an excitatory action on mammalian nociceptors. | |||||||||||||||||||||
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