SB 452533 (Standard)
SB 452533 (Standard) is the analytical standard of SB 452533 (HY-108458). This product is intended for research and analytical applications. SB 452533 is a potent and selective TRPV1 antagonist with the pKb of 7.8.
For research use only. We do not sell to patients.
- CAS No.: 459429-39-1
- Formula: C18H22BrN3O
- Molecular Weight:376.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 459429-39-1
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Molecular Weight 376.29
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Formula C18H22BrN3O
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SMILES
O=C(NCCN(CC)C1=CC=CC(C)=C1)NC2=CC=CC=C2Br
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Harshad K Rami, et al. Discovery of small molecule antagonists of TRPV1. Bioorg Med Chem Lett. 2004 Jul 16;14(14):3631-4. [Content Brief]
[2]. Parisa Vahidi Ferdowsi, et al. TRPV1 Activation by Capsaicin Mediates Glucose Oxidation and ATP Production Independent of Insulin Signalling in Mouse Skeletal Muscle Cells. Cells. 2021 Jun 21;10(6):1560. [Content Brief]
[3]. Lin Ming Lu, et al. Effect of small dose capsaicin for treatment of pulmonary fibrosis in mice and its mechanism. Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2020 May;36(3):216-222. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)