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AMG-8562

AMG-8562 is a TRPV1 modulator. AMG-8562 blocks Capsaicin (HY-10448) activation of TRPV1 without affecting heat activation of TRPV1. AMG-8562 potentiates pH 5 activation of TRPV1. AMG-8562 blocks capsaicin-induced flinching behavior in pain models. AMG-8562 produces significant efficacy in CFA- and skin incision-induced thermal hyperalgesia, and in the Acetic acid (HY-Y0319)-induced writhing models.

For research use only. We do not sell to patients.

  • CAS No.: 1041478-78-7
  • Formula: C24H25F3N2O2
  • Molecular Weight:430.47
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • AMG-8562 Chemical Structure
    AMG-8562 Chemical Structure
CAS No.: 1041478-78-7
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Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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  • AMG-8562 Chemical Structure
    AMG-8562 Chemical Structure
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  • AMG-8562