CB2 receptor antagonist 1
Hexyl resorcinol derivative 29 has been proved to be a CB2 selective competitive antagonist / reverse agonist with good potency. Olivanol and 5- (2-methyloctane-2-yl) resorcinol derivatives 23 and 24 showed significant antinociceptive activity. Compound 24 was shown to activate cannabinoid and TRPV1 receptors.
For research use only. We do not sell to patients.
- CAS No.: 2772693-05-5
- Formula: C28H47NO3
- Molecular Weight:445.68
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | EC50 |
173.6 nM
Compound: 29
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Agonist activity at human CB2 receptor expressed in CHO cell membrane assessed as inhibition of [35S]-GTPgammaS binding incubated for 1 hr by by liquid scintillation counting assay
Agonist activity at human CB2 receptor expressed in CHO cell membrane assessed as inhibition of [35S]-GTPgammaS binding incubated for 1 hr by by liquid scintillation counting assay
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[PMID: 32340793] |
Chemical Information
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CAS No. 2772693-05-5
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Molecular Weight 445.68
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Formula C28H47NO3
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SMILES
CCCCCCC1=CC=C(C=C1OC)OCCCCCCCCCCC(NCC2CC2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CB2 receptor antagonist 1 Related Classifications
HY-147707 Related Classifications
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