2. MAPK/ERK Pathway NF-κB Stem Cell/Wnt
  3. NF-κB ERK
  4. Resolvin D5

Resolvin D5 is a prolytic mediator (SPM) with anti-inflammatory activity derived from oxidized lipids DHA. Resolvin D5 inhibits Th17 cell differentiation and promotes regulatory T cell differentiation, and inhibits CD4+ T cell proliferation. Resolvin D5 attenuates osteoclast differentiation and interferes with osteoclastogenesis. Resolvin D5 also regulates ERK phosphorylation and nuclear translocation of NF-kappaB. Resolvin D5 could be used in rheumatoid arthritis research.

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Resolvin D5 Chemical Structure

Resolvin D5 Chemical Structure

CAS No. : 578008-43-2

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Resolvin D5 Related Antibodies

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Description

Resolvin D5 is a prolytic mediator (SPM) with anti-inflammatory activity derived from oxidized lipids DHA. Resolvin D5 inhibits Th17 cell differentiation and promotes regulatory T cell differentiation, and inhibits CD4+ T cell proliferation. Resolvin D5 attenuates osteoclast differentiation and interferes with osteoclastogenesis. Resolvin D5 also regulates ERK phosphorylation and nuclear translocation of NF-kappaB. Resolvin D5 could be used in rheumatoid arthritis research[1][2].

Molecular Weight

360.49

Formula

C22H32O4
CAS No.
SMILES

CC/C=C\C[C@H](O)/C=C/C=C\C/C=C\C=C\[C@@H](O)C/C=C\CCC(O)=O
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

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Resolvin D5 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Resolvin D5578008-43-2Resolvin D 5Resolvin D-5NF-κBERKNuclear factor-κBNuclear factor-kappaBExtracellular signal regulated kinasesInhibitorinhibitorinhibit

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