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Plasmodium+falciparum

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acetyl-CoA synthetase (1) Adrenergic Receptor (2) Akt (2) Aminoacyl-tRNA Synthetase (2) Aminopeptidase (1) Antibiotic (12) Apoptosis (12) Bacterial (24) Bcl-2 Family (2) Beta-secretase (2) Caspase (1) Cathepsin (3) CDK (1) COX (1) CXCR (1) Cyclic GMP-AMP Synthase (1) Cytochrome P450 (1) Dihydrofolate reductase (DHFR) (5) Dihydroorotate Dehydrogenase (5) DNA Alkylator/Crosslinker (1) DNA Methyltransferase (4) DNA/RNA Synthesis (4) Drug Derivative (3) Drug Intermediate (1) Drug Isomer (2) Drug Metabolite (1) Endogenous Metabolite (5) Enolase (1) Eukaryotic Initiation Factor (eIF) (1) Farnesyl Transferase (1) FKBP (1) Fungal (3) GABA Receptor (2) Glucosylceramide Synthase (GCS) (1) GLUT (2) GSK-3 (2) HCV (2) HDAC (5) HMG-CoA Reductase (HMGCR) (1) HSP (1) HSV (1) Huntingtin (1) Isotope-Labeled Compounds (2) Lactate Dehydrogenase (1) Ligands for E3 Ligase (1) MAP4K (1) MicroRNA (2) Mitochondrial Metabolism (1) mTOR (2) Na+/K+ ATPase (2) NF-κB (1) Parasite (189) Phosphodiesterase (PDE) (1) PI3K (4) PI4K (7) Potassium Channel (1) PROTACs (2) Proteasome (2) Protein Arginine Deiminase (2) Reactive Oxygen Species (ROS) (3) Reference Standards (10) SARS-CoV (1) Ser/Thr Kinase (1) SHMT (1) STING (1) Syk (1) TrxR (2) Virus Protease (1)
By Research Areas:	Cancer (37) Cardiovascular Disease (3) Endocrinology (1) Infection (204) Inflammation/Immunology (11) Metabolic Disease (5) Neurological Disease (2)

By Targets:

Acetyl-CoA synthetase (1)

Adrenergic Receptor (2)

Akt (2)

Aminoacyl-tRNA Synthetase (2)

Aminopeptidase (1)

Antibiotic (12)

Apoptosis (12)

Bacterial (24)

Bcl-2 Family (2)

Beta-secretase (2)

Caspase (1)

Cathepsin (3)

CDK (1)

COX (1)

CXCR (1)

Cyclic GMP-AMP Synthase (1)

Cytochrome P450 (1)

Dihydrofolate reductase (DHFR) (5)

Dihydroorotate Dehydrogenase (5)

DNA Alkylator/Crosslinker (1)

DNA Methyltransferase (4)

DNA/RNA Synthesis (4)

Drug Derivative (3)

Drug Intermediate (1)

Drug Isomer (2)

Drug Metabolite (1)

Endogenous Metabolite (5)

Enolase (1)

Eukaryotic Initiation Factor (eIF) (1)

Farnesyl Transferase (1)

FKBP (1)

Fungal (3)

GABA Receptor (2)

Glucosylceramide Synthase (GCS) (1)

GLUT (2)

GSK-3 (2)

HCV (2)

HDAC (5)

HMG-CoA Reductase (HMGCR) (1)

HSP (1)

HSV (1)

Huntingtin (1)

Isotope-Labeled Compounds (2)

Lactate Dehydrogenase (1)

Ligands for E3 Ligase (1)

MAP4K (1)

MicroRNA (2)

Mitochondrial Metabolism (1)

mTOR (2)

Na+/K+ ATPase (2)

NF-κB (1)

Parasite (189)

Phosphodiesterase (PDE) (1)

PI3K (4)

PI4K (7)

Potassium Channel (1)

PROTACs (2)

Proteasome (2)

Protein Arginine Deiminase (2)

Reactive Oxygen Species (ROS) (3)

Reference Standards (10)

SARS-CoV (1)

Ser/Thr Kinase (1)

SHMT (1)

STING (1)

Syk (1)

TrxR (2)

Virus Protease (1)

By Research Areas:

Cancer (37)

Cardiovascular Disease (3)

Endocrinology (1)

Infection (204)

Inflammation/Immunology (11)

Metabolic Disease (5)

Neurological Disease (2)

213

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0770

Artemotil 1 Publications Verification β-Arteether; (+)-Arteether; Arteether	CXCR Parasite	Infection Cancer
Artemotil (β-Arteether) has antimalarial activity for the treatment of chloroquine-resistant *Plasmodium falciparum* malaria with an IC₅₀ of 1.61 nM. Artemotil also has central nervous system (CNS) neurotoxicity and anorectic toxicity in rats, dogs and monkeys .

HY-128204

AN3661 2 Publications Verification	Parasite	Infection
AN3661, a potent antimalarial lead compound, targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue subunit 3 (PfCPSF3). AN3661 inhibits Plasmodium falciparum laboratory-adapted strains (mean IC₅₀=32 nM), Ugandan field isolates (mean ex vivo IC₅₀=64 nM), and murine P. berghei and P. falciparum infections .

HY-B0529A

Azlocillin sodium salt 1 Publications Verification Sodium azlocillin	Bacterial Parasite Antibiotic	Infection
Azlocillin sodium salt (Sodium azlocillin), a semisynthetic penicillin, is a broad spectrum β-lactam antibiotic. Azlocillin sodium salt shows antipseudomonal activity, and also potent against the malarial parasite Plasmodium falciparum .

HY-153007

DHFR-IN-5	Dihydrofolate reductase (DHFR)	Infection
DHFR-IN-5 is a potent and orally active dihydrofolate reductase (DHFR) inhibitor with a K_i value of 0.54 nM for quadruple mutant Plasmodium falciparum DHFR. DHFR-IN-5 shows anti-malaria activity .

HY-126130

LysRs-IN-2 1 Publications Verification	Aminoacyl-tRNA Synthetase	Infection
LysRs-IN-2 is a lysyl-tRNA synthetase (KRS) inhibitor with IC₅₀s of 0.015 μM and 0.13 μM for Plasmodium falciparum lysyl-tRNA synthetase (PfKRS) and Cryptosporidium parvum lysyl-tRNA synthetase (CpKRS), respectively .

HY-N7583

Norcaesalpinin E	Parasite	Infection
Norcaesalpinin E, a C-17-norcassane-type diterpene found in Caesalpinia crista, is a *Plasmodium falciparum* growth inhibitor with an IC₅₀ of 90 nM. Norcaesalpinin E induces dose-dependent growth inhibition of Plasmodium falciparum. Norcaesalpinin E can be used for the research of malaria .

HY-129651

SHMT-IN-1	SHMT	Infection
SHMT-IN-1 is a Plasmodium falciparum Serine Hydroxymethyltransferase (PfSHMT) inhibitor with an IC₅₀ of 350 nM. SHMT-IN-1 can be used for the research of malaria .

HY-100358

AQ-13 dihydrochloride	Parasite	Infection
AQ-13 dihydrochloride is an aminoquinoline antimalarial agent that is effective against drug-resistant strains of Plasmodium falciparum.

HY-15873

FTI 276	Farnesyl Transferase	Cancer
FTI-276 is a protein farnesyl transferase (PFT) inhibitor with IC₅₀s of 0.9 and 0.5 nM for Plasmodium falciparum and human.

HY-148433

SpdSyn binder-1	Parasite	Infection Inflammation/Immunology
SpdSyn binder-1 is a weak binder, which binds in the active site of plasmodium falciparum spermidine synthase. SpdSyn binder-1 can be used for the research of malaria .

HY-135578

Artelinic acid	Parasite	Infection
Artelinic acid, a derivative of Artemisinin, is an antimalarial agent for the treatment of multidrug resistant strains of Plasmodium falciparum. Artelinic acid can be administered by various routes of administration, including intravenous, intramuscular and oral routes .

HY-117015

Purfalcamine	Parasite	Infection
Purfalcamine is an orally active, selective Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) inhibitor with an IC₅₀ of 17 nM and an EC₅₀ of 230 nM. Purfalcamine has antimalarial activity and causes malaria parasites developmental arrest at the schizont stage .

HY-A0163D

trans-Clopenthixol (E)-Clopenthixol	Antibiotic Bacterial Parasite	Infection
trans-Clopenthixol ((E)-Clopenthixol) is an antibiotic, without neuroleptic effect. trans-Clopenthixol can be used to inhibit Pseudomonas aeruginosa and Plasmodium falciparum in vitro .

HY-135648

PfDHODH-IN-1	Parasite Lactate Dehydrogenase DNA/RNA Synthesis	Infection
PfDHODH-IN-1 is an analogue of the active metabolite of Leflunomide. PfDHODH-IN-1 is a Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitor. PfDHODH-IN-1 has antimalarial activity .

HY-W109038

4-Propylcatechol	Drug Derivative Parasite	Infection
4-Propylcatechol is an Allylpyrocatechol (HY-124127) analog. 4-Propylcatechol shows anti-malarial activity against Plasmodium falciparum CDC-1 with an IC₅₀ of 32 µM .

HY-112435

UCT943	PI4K Parasite	Infection
UCT943 is a next-generation Plasmodium falciparum PI4K inhibitor. UCT943 inhibits the P. vivax PI4K (PvPI4K) enzyme with an IC₅₀ of 23 nM .

HY-B1401

Euquinine Quinine ethyl carbonate	Parasite	Infection
Euquinine is an odorless salt that can be used as a substitute for quinine. Euquinine has anti-Plasmodium falciparum activity. Euquinine can be used for the study of multidrug resistance and bioavailability of Plasmodium falciparum .

HY-159637

IWY357 NVP-IWY357	Parasite	Infection
IWY357 is a long-acting, blood-stage inhibitor of Plasmodium falciparum .

HY-N10928

Lettowienolide	Parasite	Infection
Lettowienolide, a geranylbenzoquinonoid, exhibits mild in vitro activity against the Plasmodium falciparum malaria parasite (IC₅₀~20 μg/mL) .

HY-N9320

13,21-Dihydroeurycomanone	Parasite	Infection
13,21-Dihydroeurycomanone, a natural compound isolated from Eurycoma longifolia root, possesses anti-parasite activity for Plasmodium falciparum and Toxoplasma gondii .

HY-121770

Rutarin	Drug Derivative Parasite Fungal	Infection
Rutarin is a Coumarin (HY-N0709) derivative with antimalarial and antifungal activities. Rutarin inhibits Plasmodium falciparum with an IC₅₀ of 88 μg/mL. Rutarin also inhibits Coniophora cerebella .

HY-N11031

Z-Antiepilepsirine	Parasite	Infection
Z-Antiepilepsirine is an amide alkaloid that can be found in Piper capense L.f. Z-Antiepilepsirine shows antiplasmodial activity with an IC₅₀ value of 27 µM for W2 strain of Plasmodium falciparum .

HY-161079

TDI-8304	Parasite	Infection
TDI-8304, a macrocyclic peptide, is a potent, species selective, and noncovalent Plasmodium falciparum (Pf20S) inhibitor. TDI-8304 shows highly selective for Pf20S over human proteasomes .

HY-121211

Digitolutein	Parasite	Infection
Digitolutein is a natural product that can be isolated from the stem bark and the roots of Morinda lucida Benth. Digitolutein effectively inhibits the growth of *Plasmodium falciparum* with an IC₅₀ value of 12.92 μg/mL. Digitolutein can be used for the research of infection .

HY-186055

Antimalarial agent 58	Parasite	Infection
Antimalarial agent 58 is a diaminoquinoline methanol compound with weak in vitro activity against Plasmodium falciparum strain D6, and no activity against Plasmodium falciparum strains W2, C235 and C2A .

HY-N8257

Dehydrobruceine A	Parasite	Infection Inflammation/Immunology
Dehydrobruceine A is a low potent antitrypanosomal agent, with an IC₅₀ of 88.5 nM for Plasmodium falciparum .

HY-W010354

2,2-Diethoxyethanol	Drug Intermediate	Infection
2,2-Diethoxyethanol is a drug intermediate used in research related to Plasmodium falciparum infection .

HY-A0163C

trans-Clopenthixol dihydrochloride (E)-Clopenthixol dihydrochloride	Antibiotic Bacterial Parasite	Infection
trans-Clopenthixol ((E)-Clopenthixol) dihydrochloride is an antibiotic agent, without neuroleptic effect. trans-Clopenthixol dihydrochloride can be used to inhibit Pseudomonas aeruginosa and Plasmodium falciparum in vitro .

HY-174393

Gamhepathiopine	Parasite Mitochondrial Metabolism	Infection
Gamhepathiopine is a thienopyrimidinone compound. Gamhepathiopine exerts antimalarial effects by targeting the Q_o site of Plasmodium falciparum cytochrome b and inhibiting the activity of complex III in the electron transport chain .

HY-149289

DNMT-IN-3	Parasite DNA Methyltransferase	Others
DNMT-IN-3 is an DNA Methyltransferase (DNMT) inhibitor, and plays an antimalarial role with IC₅₀ of 60 nM against Plasmodium falciparum (Plasmodium). DNMT-IN-3 can be used for malaria related research .

HY-122274

MMV666693	Parasite	Infection
MMV666693 is a translation inhibitor specific for Plasmodium falciparum. MMV666693 has low cytotoxicity in human fibroblasts (IC₅₀>32 µM) and can be used in the development of antimalarial drugs .

HY-111746

CWHM-1008 1 Publications Verification	Parasite	Infection
CWHM-1008 is a potent and orally active antimalarial agent, with EC₅₀ values of 46 and 21 nM against agent-sensitive Plasmodium falciparum 3D7 and drug-resistant Dd2 strains, respectively .

HY-175362

WEHI-326	Parasite	Infection
WEHI-326 is a potent antimalarial agent targeting Plasmodium falciparum ROM8 and CSC1 proteins (IC₅₀=0.006 μM). WEHI-326 is promising for research of malaria .

HY-N7648

Atherosperminine Atherospermine	Parasite Phosphodiesterase (PDE)	Infection
Atherosperminine (Atherospermine) is a phosphodiesterase inhibitor. Atherosperminine inhibits growth of chloroquine-resistant Plasmodium falciparum. Atherosperminine scavenges DPPH free radicals, exhibits ferric reducing power, and chelates metal ions. Atherosperminine can be used for the research of malaria .

HY-175732

PI4Kβ-IN-1	PI4K Parasite	Infection
PI4Kβ-IN-1 is an orally active and selective PI4Kβ inhibitor, with an IC₅₀ of 0.9 nM. PI4Kβ-IN-1 exhibits inhibitory activity against all stages of the P. falciparum life cycle, including blood, liver, and transmission stages. PI4Kβ-IN-1 demonstrates potent antimalarial efficacy in the mouse model infected with Plasmodium falciparum. PI4Kβ-IN-1 can be used for the study of malaria caused by Plasmodium falciparum .

HY-161801

MMV006833 M-833	Parasite	Infection
MMV006833 is an inhibitor for Plasmodium falciparum. MMV006833 targets the lipid-transfer protein PfSTART1 and inhibits the development of Plasmodium falciparum at the ring stage .

HY-148178

MMV688533	Parasite	Infection
MMV688533 is an antimalarial agent. MMV688533 interferes with intracellular trafficking, lipid utilization, and endocytosis pathways in Plasmodium falciparum. MMV688533 rapidly kills asexual blood-stage Plasmodium falciparum and Plasmodium vivax parasites in vitro and reduces parasitemia in a Plasmodium falciparum NSG mouse model. MMV688533 can be used for the research of malaria .

HY-158818

DXR-IN-2	Parasite	Infection
DXR-IN-2 is a 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) inhibitor and an antimalarial agent (IC₅₀: 0.1062 μM for Plasmodium falciparum DXR and 0.369 μM for Plasmodium falciparum). DXR-IN-2 inhibits Plasmodium falciparum growth by suppressing the methyl erythritol phosphate (MEP) pathway via DXR .

HY-122385

Dabequin phosphate	Parasite	Infection
Dabequin phosphate is an antimalarial agent, that exhibits inhibitory activity against Plasmodium falciparum .

HY-170848

Antimalarial agent 48	Parasite	Infection
Antimalarial agent 48 (Compound 15a) is a triazine-class compound with antimalarial activity, showing inhibitory concentrations of 280 nM against Plasmodium falciparum K1 and 290 nM against Plasmodium falciparum FCR3. Antimalarial agent 48 is expected to be useful for research in the field of antimalarial infections .

HY-W779377

Erythromycin B	Parasite	Infection
Erythromycin B has anti-malarial activity and effectively inhibits the asexual reproduction of Plasmodium falciparum .

HY-145233

PfPKG-IN-1	Parasite	Infection
PfPKG-IN-1 is a imidazole-based inhibitor of Plasmodium falciparum cGMP-dependent protein kinase (PfPKG).

HY-163833

MMV1634566	Parasite	Infection Cancer
MMV1634566 is a potent antimalarial agent. MMV1634566 inhibits Plasmodium falciparum. MMV1634566 shows cytotoxicity .

HY-125419

Amythiamicin B	Antibiotic Parasite Bacterial	Infection
Amythiamicin B is a trisubstituted pyridine thiopeptide with antibiotic properties against Gram-positive bacteria and activity against Plasmodium falciparum .

HY-170840

Antimalarial agent 47	Parasite	Infection
Antimalarial agent 47 (compound F14) is an antimalarial compound, with an IC₅₀ of 235 nM for the Plasmodium falciparum W2 strain .

HY-155130

Antimalarial agent 31	Parasite	Infection
Antimalarial agent 31 (compound 7k) is an orally active Plasmodium falciparum aspartic protease plasmepsin X (PMX) inhibitor .

HY-N12452

Myrrhterpenoid O	Parasite	Infection
Myrrhterpenoid O (Compound 18) is a sesquiterpenoid compound that exhibits good inhibitory activity against Plasmodium falciparum (IC₅₀ = 21 μM) .

HY-N13885

Amythiamicin A	Antibiotic Bacterial Parasite	Infection
Amythiamicin A is an antimicrobial antibiotic against Gram-positive bacteria (including methicillin-resistant Staphylococcus aureus (MRSA)) and activity against Plasmodium falciparum .

HY-N12538

trans-Cinnamic anhydride	Parasite	Infection
trans-Cinnamic anhydride is a Parasite inhibitor tnat can be isolated from Cinnamomum zeylanicum and exhibits moderate activity against Plasmodium falciparum .

HY-N13288

Cordysinin C/D	Parasite	Infection
Cordysinin C/D (compound 9) is a potential anti-plasmodial compound that can effectively inhibit Plasmodium falciparum 3D7 strain .

Cat. No.	Product Name	Type

HY-143218

TPE-MI

10+ Cited Publications

Tetraphenylethene maleimide

Fluorescent Dyes

TPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasites Plasmodium falciparum .

Cat. No.	Product Name	Type

HY-134421

2-Butenoyl coenzyme A lithium

Biochemical Assay Reagents

2-Butenoyl coenzyme A lithium is an inactivator and a substrate of Plasmodium falciparum enoyl-β-hydroxyacyl-acyl carrier protein (ACP) reductase and other enoyl-CoA reductases, and it is also the lithium salt of trans-2-methyl-2-butenoyl coenzyme A. 2-Butenoyl coenzyme A lithium acts on short-chain and medium-chain coenzyme A dehydrogenases as well as glutaryl-CoA dehydrogenase, and shows no activity against wild-type isovaleryl-CoA dehydrogenase. 2-Butenoyl coenzyme A lithium functions as a metabolite in the L-isoleucine catabolic pathway, and can serve as a substrate in the activity assay of 3-ketothiolase. 2-Butenoyl coenzyme A lithium is applicable to research related to 3-ketothiolase deficiency .

Cat. No.	Product Name	Target	Research Area

HY-P5344

Dabcyl-LNKRLLHETQ-Edans Fluorigenic PEXEL peptide	Parasite	Others
Dabcyl-LNKRLLHETQ-Edans (Fluorigenic PEXEL peptide) is a biological active peptide. (This FRET substrate peptide for Plasmepsin V (PMV) is derived from the conserved Plasmodium Export Element (PEXEL) motif of Histidine-Rich Protein II (HRPII). PMV is an ER aspartic protease that recognizes and cleaves the RXL sequence within the PEXEL motif of proteins exported by human malaria parasite Plasmodium falciparum, allowing them to translocate into host erythrocytes.)

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0941

beta-Mangostin 4 Publications Verification β-Mangostin	Infection Xanthones Classification of Application Fields Guttiferae Phenols Polyphenols Garcinia mangostana Linn. Plants Disease Research Fields Source Classification Cancer	Bacterial Parasite Apoptosis
beta-Mangostin (β-Mangostin) is a xanthone compound present in Cratoxylum arborescens, with antibacterial and antimalarial activities. beta-Mangostin exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg/mL. beta-Mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC₅₀ of 3.00 μg/mL. beta-Mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic) .

HY-N6742

Borrelidin 1 Publications Verification Treponemycin	Infection Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Anti-parasitic Antibacterial Disease Research Disease Research Fields Source Classification	CDK Parasite Apoptosis Antibiotic
Borrelidin (Treponemycin) is a bacterial and eukaryal threonyl-tRNA synthetase inhibitor which is a nitrile-containing macrolide antibiotic isolated from Streptomyces rochei . Borrelidin is an inhibitor of Cdc28/Cln2 of the budding yeast, with an IC₅₀ of 24 μM . Borrelidin is a potent angiogenesis inhibitor, with an IC₅₀ of 0.8 nM. Borrelidin induces apoptosis in the tube-forming cells . Borrelidin has strong antimalarial activities, with IC₅₀s of 1.9 nM and 1.8 nM against K1 and FCR3 strains of Plasmodium falciparum, respectively .

HY-B0770

Artemotil 1 Publications Verification β-Arteether; (+)-Arteether; Arteether	Natural Products Classification of Application Fields Artemisia carvifolia Buch.-Ham. ex Roxb. Plants Compositae Disease Research Fields Source Classification Cancer	CXCR Parasite
Artemotil (β-Arteether) has antimalarial activity for the treatment of chloroquine-resistant *Plasmodium falciparum* malaria with an IC₅₀ of 1.61 nM. Artemotil also has central nervous system (CNS) neurotoxicity and anorectic toxicity in rats, dogs and monkeys .

HY-N1255

Scoulerine (-)-Scoulerine; Discretamine	Alkaloids Structural Classification other families Classification of Application Fields Phenols Polyphenols Plants Isoquinoline Alkaloids Disease Research Fields Source Classification Cancer	Bcl-2 Family Apoptosis mTOR GABA Receptor PI3K Adrenergic Receptor Beta-secretase Akt
Scoulerine ((-)-Scoulerine; Discretamine) hydrochloride is a multi-target inhibitor with anti-tumor and antioxidant activities. Scoulerine mainly targets the PI3K/Akt/mTOR signaling axis and α1D-adrenergic receptor, disrupts microtubule structure, and induces cell cycle arrest and apoptosis. Scoulerine effectively inhibits mitochondrial dehydrogenase activity, targets GABA receptors and BACE1, and suppresses the proliferation, migration, invasion, epithelial-mesenchymal transition and stem cell properties of cancer cells. Scoulerine also exhibits multiple pharmacological activities including anti-Plasmodium falciparum, antibacterial, antiemetic and antitussive effects, and regulates endoplasmic reticulum stress and mitochondrial function (modulates Bax, Bcl-2 and cytochrome c). Scoulerine is applicable to research related to leukemia, ovarian cancer, and colorectal cancer .

HY-121362

Evernic Acid	Structural Classification other families Classification of Application Fields Ketones, Aldehydes, Acids Plants Inflammation/Immunology Disease Research Fields Source Classification	Bacterial Endogenous Metabolite TrxR
Evernic Acid is an orally active thioredoxin reductase 1 (TrxR1) inhibitor and antiproliferative agent. Evernic Acid inhibits the proliferation and migration of human breast cancer cells. Evernic Acid blocks the NF-κB pathway by inhibiting p65 nuclear translocation and IκBα phosphorylation, thereby suppressing downstream inflammatory mediators. Evernic Acid acts as an antioxidant, anti-inflammatory agent and neuroprotective agent, protects neurons from cell death, mitochondrial dysfunction and oxidative stress damage, reduces astrocyte activation, and ameliorates dopaminergic neuron loss and neuroinflammation. Evernic Acid inhibits enoyl reductases FabI and FabZ of Plasmodium falciparum. Evernic Acid downregulates the expression of lasB and rhlA genes in Pseudomonas aeruginosa, inhibits quorum sensing and biofilm formation, and exerts antibacterial activity against Gram-positive bacteria, Gram-negative bacteria and fungi. Evernic Acid is applicable to research related to breast cancer, Parkinson's disease, bacterial infections and fungal infections .

HY-N2815

Ursolic acid acetate Acetylursolic acid; 3-Acetylursolic acid	Triterpenes other families Classification of Application Fields Terpenoids Plants Disease Research Fields Source Classification Cancer	Parasite HSP
Ursolic acid acetate (Acetylursolic acid) is a triterpenoid compound and an inhibitor of Plasmodium falciparum heat shock protein 90 (PfHsp90) with a K_D of 8.16 μM. Ursolic acid acetate is cytotoxic to KB cells, with an IC₅₀ value of 8.4 μM. Ursolic acid acetate can be used in tumor and antimalarial research .

HY-129476

L-Canaline	Infection other families Classification of Application Fields Amino acids Plants Endogenous metabolite Disease Research Fields Source Classification	Parasite Endogenous Metabolite
L-Canaline is a nonprotein amino acid stored in many leguminous plants. L-Canaline is a cytotoxic metabolite catalyzed by L-canavanine and its arginase. L-Canaline is a potent and irreversible inhibitor of ornithine aminotransferase. L-Canaline inhibits the growth of the malaria parasite *Plasmodium falciparum* with an IC₅₀ of 297 nM. L-Canaline has anticancer and antiproliferative effects .

HY-N0352

Tuberostemonine 1 Publications Verification	Infection Alkaloids other families Pyrrole Alkaloids Classification of Application Fields Plants Disease Research Fields Source Classification	Parasite
Tuberostemonine is a stenine alkaloid that can be isolated from Stemona tuberosa and Stemona sessifolia. Tuberostemonine is an antimalarial agent that has inhibitory activity against Ferredoxin-NADP ⁺ reductases (FNRs) from Plasmodium falciparum (PfFNR). Tuberostemonine can reduce the number of citric acid-induced coughs in guinea pigs. Tuberostemonine decreases bronchoalveolar lavage fluid (BALF), neutrophil and macrophage infiltration and reduces peribronchial and perivascular inflammatory cell infiltration in mouse model of acute lung inflammation. Tuberostemonine has a level of activity as a feeding deterrent .

HY-42034

Hydroquinine Dihydroquinine	Alkaloids Classification of Application Fields Rubiaceae Cinchona calisaya Wedd. Quinoline Alkaloids Plants Inflammation/Immunology Disease Research Fields Source Classification	Bacterial Parasite Reactive Oxygen Species (ROS) Protein Arginine Deiminase
Hydroquinine (Dihydroquinine) is an anti-bacterial agent that inhibits both Gram-positive and Gram-negative bacteria. Hydroquinine inhibits the growth of multidrug-resistant pseudomonas aeruginosa via the suppression of the arginine deiminase pathway genes. Hydroquinine inhibits Plasmodium falciparum and Plasmodium berghei. Hydroquinine displays anti-malarial and demelanizing activities. Hydroquinine effectively induces specific RND-type efflux pump systems in Pseudomonas aeruginosa, particularly the MexCD-OprJ and MexXY efflux pumps. Hydroquinine inhibits Pseudomonas aeruginosa adhesion and biofilm formation. Hydroquinine serves as a precursor for derivatives such as C9 epihydroquinine, 9-acetoxy-10,11-dihydroquinine, and 10,11-dihydroquinine monohydrochloride .

HY-134421

2-Butenoyl coenzyme A lithium	Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	HMG-CoA Reductase (HMGCR)
2-Butenoyl coenzyme A lithium is an inactivator and a substrate of Plasmodium falciparum enoyl-β-hydroxyacyl-acyl carrier protein (ACP) reductase and other enoyl-CoA reductases, and it is also the lithium salt of trans-2-methyl-2-butenoyl coenzyme A. 2-Butenoyl coenzyme A lithium acts on short-chain and medium-chain coenzyme A dehydrogenases as well as glutaryl-CoA dehydrogenase, and shows no activity against wild-type isovaleryl-CoA dehydrogenase. 2-Butenoyl coenzyme A lithium functions as a metabolite in the L-isoleucine catabolic pathway, and can serve as a substrate in the activity assay of 3-ketothiolase. 2-Butenoyl coenzyme A lithium is applicable to research related to 3-ketothiolase deficiency .

HY-N7583

Norcaesalpinin E	Structural Classification Leguminosae Caesalpinia crista L. Terpenoids Diterpenoids Plants Source Classification	Parasite
Norcaesalpinin E, a C-17-norcassane-type diterpene found in Caesalpinia crista, is a *Plasmodium falciparum* growth inhibitor with an IC₅₀ of 90 nM. Norcaesalpinin E induces dose-dependent growth inhibition of Plasmodium falciparum. Norcaesalpinin E can be used for the research of malaria .

HY-N5109

Cheilanthifoline	Infection Alkaloids Structural Classification Monophenols other families Classification of Application Fields Phenols Plants Isoquinoline Alkaloids Disease Research Fields Source Classification	Parasite
Cheilanthifoline, an alkaloid, is isolated from Corydalis calliantha. Cheilanthifoline exhibits antiplasmodial activities against Plasmodium falciparum, with IC₅₀s of 0.90 μg/mL and 1.22 μg/mL for wild type (TM4) and multidrug resistant (K1) strains, respectively .

HY-N6009

8-Deoxygartanin	Infection other families Xanthones Classification of Application Fields Phenols Polyphenols Plants Disease Research Fields Source Classification	Parasite NF-κB
8-Deoxygartanin, a prenylated xanthones from G. mangostana, is a selective inhibitor of butyrylcholinesterase (BChE) . 8-Deoxygartanin exhibits antiplasmodial activity with an IC₅₀ of 11.8 μM for the W2 strain of Plasmodium falciparum . 8-Deoxygartanin inhibits NF-κB (p65) activation with an IC₅₀ of 11.3 μM .

HY-N5005

Guanfu base H Atisinium chloride	Infection Alkaloids Classification of Application Fields Ranunculaceae Quinoline Alkaloids Aconitum carmichaeli Debx. Plants Disease Research Fields Source Classification	Parasite
Guanfu base H (Atisinium chloride) is a diterpenoid alkaloid isolated from Aconitum coreanum and has antiplasmodial activity against the malarial *Plasmodium falciparum* strains TM4/8.2 (wild type) and K1CB1 with IC₅₀ values of 4 μM and 3.6 μM, respectively .

HY-N15159

Cladophorol A	Structural Classification Marine algae Marine natural products Phenols Polyphenols Source Classification	Cyclic GMP-AMP Synthase STING Parasite
Cladophorol A is a cyclic GMP-AMP synthase (cGAS) inhibitor. Cladophorol A binds to the conserved adenosine nucleobase binding site within the cGAS active site to inhibit its catalytic activity. Cladophorol A effectively inhibits the overactivation of the cGAS-STING pathway with an IC₅₀ of 370 nM. Cladophorol A inhibits asexual blood-stage Plasmodium falciparum with an EC₅₀ of 0.7 μg/mL. Cladophorol A can be used for the researches of inflammatory disease and malaria .

HY-N10928

Lettowienolide	Quinones Stellaria media (L.) Villars Phenols Benzene Quinones Plants Caryophyllaceae Source Classification	Parasite
Lettowienolide, a geranylbenzoquinonoid, exhibits mild in vitro activity against the Plasmodium falciparum malaria parasite (IC₅₀~20 μg/mL) .

HY-N9320

13,21-Dihydroeurycomanone	Infection other families Classification of Application Fields Ketones, Aldehydes, Acids Eurycoma longifolia Jack Plants Disease Research Fields Source Classification	Parasite
13,21-Dihydroeurycomanone, a natural compound isolated from Eurycoma longifolia root, possesses anti-parasite activity for Plasmodium falciparum and Toxoplasma gondii .

HY-121770

Rutarin	Rutaceae Coumarins Glycosmis pseudoracemosa (Guill.) Swinge Phenylpropanoids Plants Source Classification	Drug Derivative Parasite Fungal
Rutarin is a Coumarin (HY-N0709) derivative with antimalarial and antifungal activities. Rutarin inhibits Plasmodium falciparum with an IC₅₀ of 88 μg/mL. Rutarin also inhibits Coniophora cerebella .

HY-N11031

Z-Antiepilepsirine	Alkaloids Piperidine Alkaloids Piper capense Piperaceae Plants Source Classification	Parasite
Z-Antiepilepsirine is an amide alkaloid that can be found in Piper capense L.f. Z-Antiepilepsirine shows antiplasmodial activity with an IC₅₀ value of 27 µM for W2 strain of Plasmodium falciparum .

HY-121211

Digitolutein	Morinda lucida Benth. Rubiaceae Plants	Parasite
Digitolutein is a natural product that can be isolated from the stem bark and the roots of Morinda lucida Benth. Digitolutein effectively inhibits the growth of *Plasmodium falciparum* with an IC₅₀ value of 12.92 μg/mL. Digitolutein can be used for the research of infection .

HY-120104

Nitidanin (±)-Nitidanin	Buxaceae Lignans Phenylpropanoids Plants Source Classification Buxus microphylla S.et Z.var. Sinica Rehd.et Wils.	Parasite HCV
Nitidanin ((±)-Nitidanin) is an antimalarial and antiviral compound that can be isolated from the wood of Xanthoxylum nitidun D. C. Nitidanin is shows IC₅₀ values of 21.2 and 18.4 μM for D6 and W2 clones of Plasmodium falciparum, respectively. Nitidanin can be used for the research of malaria and virus infection .

HY-N15748

Pelorol (-)-Pelorol	Terpenoids Sesquiterpenes Marine natural products Sponge Source Classification	Parasite
Pelorol ((-)-Pelorol) is a sesquiterpene found in the tropical marine sponge Dactylospongia elegans. Pelorol has weak antitrypanosomal activity with an IC₅₀ of 17.4 μg/mL and antiplasmodial activity against Plasmodium falciparum clones K1 and NF54 with IC₅₀ values of 786 ng/mL and 1911 ng/mL, respectively. Pelorol is promising for research of parasitic diseases, such as trypanosomiasis and malaria .

HY-N10096

Epoxyazadiradione	Infection Triterpenes other families Classification of Application Fields Terpenoids Plants Disease Research Fields Biological Pesticide Research Agricultural Research Source Classification	Parasite
Epoxyazadiradione is a limonoid purified from neem (Azadirachta indica) fruits. Epoxyazadiradione inhibits the tautomerase activity of MIF of both human (huMIF) and malaria parasites (Plasmodium falciparum (PfMIF) and Plasmodium yoelii (PyMIF)) non-competitively in a reversible fashion (K_i, 2.11-5.23 μM). Epoxyazadiradione has the potential against proinflammatory reactions induced by MIF of both malaria parasites and human .

HY-N2891

Aristolactam A II Aristololactam A II	Piper longum Linn. Structural Classification Alkaloids Pyrrole Alkaloids Piperaceae Plants Source Classification	Parasite COX
Aristolactam A II (Aristololactam A II) is a weak COX inhibitor with cytotoxic and anti-plasmodial activities. Aristolactam A II exhibits inhibitory activity against Chloroquine (HY-17589A)-sensitive strains, and exerts its inhibitory effect on Plasmodium falciparum growth by inducing cell membrane damage marked by LDH release. Aristolactam A II can be applied to the research of malaria-related mechanisms .

HY-N8257

Dehydrobruceine A	Simaroubaceae Classification of Application Fields Terpenoids Diterpenoids Plants Inflammation/Immunology Disease Research Fields Source Classification Brucea javanica (L.) Merr.	Parasite
Dehydrobruceine A is a low potent antitrypanosomal agent, with an IC₅₀ of 88.5 nM for Plasmodium falciparum .

HY-W010354

2,2-Diethoxyethanol	Structural Classification Natural Products Cestrum nocturnum Linn. Solanaceae Plants Source Classification	Drug Intermediate
2,2-Diethoxyethanol is a drug intermediate used in research related to Plasmodium falciparum infection .

HY-N7648

Atherosperminine Atherospermine	Infection Alkaloids Structural Classification Classification of Application Fields Other Alkaloids Fissistigma glaucescens Plants Annonaceae Disease Research Fields Source Classification	Parasite Phosphodiesterase (PDE)
Atherosperminine (Atherospermine) is a phosphodiesterase inhibitor. Atherosperminine inhibits growth of chloroquine-resistant Plasmodium falciparum. Atherosperminine scavenges DPPH free radicals, exhibits ferric reducing power, and chelates metal ions. Atherosperminine can be used for the research of malaria .

HY-N0352R

Tuberostemonine (Standard)	Alkaloids Structural Classification other families Pyrrole Alkaloids Plants Source Classification	Reference Standards Parasite
Tuberostemonine (Standard) is the analytical standard of Tuberostemonine. This product is intended for research and analytical applications. Tuberostemonine is a stenine alkaloid that can be isolated from Stemona tuberosa and Stemona sessifolia. Tuberostemonine is an antimalarial agent that has inhibitory activity Ferredoxin-NADP ⁺ reductases (FNRs) from Plasmodium falciparum (PfFNR). Tuberostemonine has a level of activity as a feeding deterrent .

HY-N16123

Chloranthalactone C	Terpenoids Sesquiterpenes Chloranthaceae Plants Chloranthus fortunei (A. Gray) Solms-Laub Source Classification	Parasite
Chloranthalactone C (Compound 43), a lindenane-type sesquiterpenoid, is an antimalarial agent. Chloranthalactone C can be isolated from plant Chloranthus japonicas Sieb. Chloranthalactone C inhibits Chloroquine (HY-17589A)-resistant Plasmodium falciparum strain Dd2 growth. Chloranthalactone C can be used for parasitic infections research .

HY-N3702

Dehydroabietinol	Structural Classification Terpenoids Verbenaceae Callicarpa bodinieri Levl. Diterpenoids Plants Source Classification	Syk
Dehydroabietinol is a SYK inhibitor with an IC₅₀ of 46.4 μM. Dehydroabietinol inhibits the growth of Trypanosoma cruzi epimastigotes, Leishmania braziliensis promastigotes and Leishmania infantum promastigotes. Dehydroabietinol indirectly inhibits the growth of Plasmodium falciparum, alters the erythrocyte membrane, and induces spherostomatocyte transformation and endovesicle formation. Dehydroabietinol can be used in studies related to immune-mediated diseases, Chagas disease, leishmaniasis and malaria .

HY-126640

Phomoxanthone A	Quinones Microorganisms Anthraquinones Source Classification	Parasite
Phomoxanthone A is a xanthone dimer, which can be isolated from Phomopsis. Phomoxanthone A exhibits antimalarial and antitubercular activities against Plasmodium falciparum (K1, multidrug-resistant strain, IC₅₀ is 0.11 µg/mL) and Mycobacterium tuberculosis (H37Ra strain, MIC is 0.50 µg/mL). Phomoxanthone A exhibits cytotoxicity in cells KB, BC-1 and Vero, IC₅₀ is 0.99, 0.51 and 1.4 µg/mL, respectively .

HY-158721

Penicinoline Marinamide	Structural Classification Alkaloids Microorganisms Indole Alkaloids Source Classification	Endogenous Metabolite Parasite
Penicinoline (Marinamide) (Compound 1), a pyrrolyl 4-quinolinone alkaloid, is a microbial secondary metabolite. Penicinoline can be isolated from endophytic fungus Penicillium sp. Penicinoline has antimalarial activity against Chloroquine (HY-17589A) sensitive strain (pf3d7) and against Chloroquine resistant strain (pfDd2) of plasmodium falciparum. Penicinoline also has strong insecticidal activity against Aphis gossypii and selective anticancer effect with significant cytotoxicity for 95-D and HepG2 cells .

HY-W779377

Erythromycin B	Microorganisms Antibiotics Source Classification	Parasite
Erythromycin B has anti-malarial activity and effectively inhibits the asexual reproduction of Plasmodium falciparum .

HY-125419

Amythiamicin B	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Parasite Bacterial
Amythiamicin B is a trisubstituted pyridine thiopeptide with antibiotic properties against Gram-positive bacteria and activity against Plasmodium falciparum .

HY-N12452

Myrrhterpenoid O	Structural Classification Commiphora myrrha (Nees) Engl. Terpenoids Sesquiterpenes Plants Burseraceae Source Classification	Parasite
Myrrhterpenoid O (Compound 18) is a sesquiterpenoid compound that exhibits good inhibitory activity against Plasmodium falciparum (IC₅₀ = 21 μM) .

HY-N13885

Amythiamicin A	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial Parasite
Amythiamicin A is an antimicrobial antibiotic against Gram-positive bacteria (including methicillin-resistant Staphylococcus aureus (MRSA)) and activity against Plasmodium falciparum .

HY-N12538

trans-Cinnamic anhydride	Natural Products Cinnamomum verum J. Presl Plants Lauraceae Source Classification	Parasite
trans-Cinnamic anhydride is a Parasite inhibitor tnat can be isolated from Cinnamomum zeylanicum and exhibits moderate activity against Plasmodium falciparum .

HY-N13288

Cordysinin C/D	Alkaloids Animals Other Alkaloids Source Classification	Parasite
Cordysinin C/D (compound 9) is a potential anti-plasmodial compound that can effectively inhibit Plasmodium falciparum 3D7 strain .

HY-N8383

Butyrolactone V	Infection Monophenols Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Phenols Disease Research Fields Source Classification	Parasite
Butyrolactone V is a butanolide compound. Butyrolactone V shows antiplasmodial activity against Plasmodium falciparum K1 with an IC₅₀ of 7.9 µg/ml .

HY-N13881

Amythiamicin C	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial Parasite
Amythiamicin C is an antimicrobial antibiotic against Gram-positive bacteria (including methicillin-resistant Staphylococcus aureus (MRSA)) and activity against Plasmodium falciparum .

HY-N8513

Brevicompanine B	Infection Alkaloids Microorganisms Classification of Application Fields Disease Research Fields Source Classification	Parasite
Brevicompanine B, a diketopiperazine alkaloid, is an antiplasmodial agent. Brevicompanine B is active against the malaria parasite Plasmodium falciparum 3D7 IC₅₀ of 35 mg/mL .

HY-N8338

Pancixanthone A	Flavonoids Guttiferae Garcinia vieillardii Pierre Plants Other Flavonoids Source Classification	Parasite
Pancixanthone A is a xanthone that can be isolated from Garcinia vieillardii. Pancixanthone A has antimalarial activity against chloroquino-resistant strains of Plasmodium falciparum with an IC₅₀ of 1.6 μg/mL .

HY-N8455

Isocudraniaxanthone A Assiguxanthone A	Flavonoids Xanthones Calophyllum caledonicum Vieill. ex Planch. & Triana Phenols Plants Calophyllaceae Other Flavonoids Source Classification	Parasite
Isocudraniaxanthone A is a xanthone that can be isolated from Garcinia vieillardii. Isocudraniaxanthone A has antimalarial activity against chloroquino-resistant strains of Plasmodium falciparum with an IC₅₀ of 2.3 μg/mL .

HY-N3957

1-(26-Hydroxyhexacosanoyl)-glycerol	Natural Products Rourea minor (Gaerth.) Leenh. Plants Connaraceae Source Classification	Parasite
1-(26-Hydroxyhexacosanoyl)-glycerol is a potent antimalarial agent. 1-(26-Hydroxyhexacosanoyl)-glycerol shows antimalarial activity with an IC₅₀ value of 9.48 µM for Plasmodium falciparum .

HY-N15562

Batzelladine L	Alkaloids Other Alkaloids Marine natural products Sponge Source Classification	Parasite
Batzelladine L is a potent *Plasmodium falciparum* inhibitor (IC₅₀= 0.4 μM). Batzelladine L shows moderate cytotoxicity to HepG2 cells (CC₅₀= 14 μM) with antimalarial properties. Batzelladine L is promising for research of antimalarial agents .

HY-N12151

Chaparrinone	Natural Products Simaroubaceae Eurycoma harmandiana Pierre Plants Source Classification	Parasite
Chaparrinone is a quassinoid that can be isolated from the root of Eurycoma harmandiana. Chaparrinone has antimalarial and cytotoxic activities against Plasmodium falciparum and P-388 cells (IC₅₀: 0.037 and 0.34 μg/mL respectively) .

HY-N10109A

Gallinamide A TFA	Natural Products Microorganisms Source Classification	SARS-CoV Parasite Cathepsin
Gallinamide A TFA is a linearly depositing peptide and a potent inhibitor of cathepsin L (CatL) (IC₅₀: 17.6 pM). Gallinamide A TFA inhibits SARS-CoV-2 infection by inhibiting CatL (EC₅₀: 28 nM). Gallinamide A TFA also inhibits Plasmodium falciparum (IC₅₀: 50 nM) .

HY-145379

Miaosporone A	Infection Quinones Structural Classification Monophenols Classification of Application Fields Anthraquinones Phenols Endogenous metabolite Disease Research Fields Source Classification	Parasite Endogenous Metabolite
Miaosporone A, an angucyclic quinone, exhibits antimalarial activity against Plasmodium falciparum K1 and antibacterial activity against Mycobacterium tuberculosis with respective IC₅₀ values of 2.5 and 2.4 μM and displays cytotoxic activities against both cancerous (MCF-7 and NCI-H187) and nonmalignant (Vero) cells .

HY-N12232

Carbazomycin D	Structural Classification Alkaloids Microorganisms Indole Alkaloids Source Classification	Parasite Bacterial
Carbazomycin D exhibits antituberculosis and antimalarial activities, that inhibits Plasmodium falciparum with an IC₅₀ > 10 μg/mL, inhibits Mycobacterium tuberculosis with MIC of 25 μg/mL. Carbazomycin D exhibits cytotoxicity in cell MCF-7, KB, NCI-H187 and Vero, with IC₅₀s of 21.3, 33.2, 12.9, and 34.3 μg/mL, respectively .

HY-N8374

Pheanthine	Alkaloids Piperidine Alkaloids Triclisia gilletii (De Wild.) Staner Plants Menispermaceae Source Classification	Parasite
Pheanthine (Compound 2) is an antiplasmodial agent, that inhibits chloroquine-resistant Plasmodium falciparum K-1 (IC₅₀ is 0.8 μM) and chloroquine-sensitive P. falciparum strain NF54 A19A (IC₅₀ of 0.03 μM). Pheanthine exhibits low cytotoxicity in human lung fibrosblast (MRC-5, IC₅₀ is 11.2 μM) and macrophages (PMM, IC₅₀ is 8 μM) .

Cat. No.	Product Name	Chemical Structure

HY-B0439S1

Sulfadoxine D3

Sulfadoxine-d₃ is a deuterium labeled Sulfadoxine (HY-B0439). Sulfadoxine is a sulfonamide that is used, usually in combination with Pyrimethamine(HY-18062), for multidrug-resistant Plasmodium falciparum and P. vivax inhibition. Unlike PYR, Sulfadoxine has no impact on HIV replication or MT-2 cell cycle progression. But also Sulfadoxine exhibits suppression on respiratory, and urinary tract infections .

HY-B0148S

Risedronic acid-d4

Risedronic acid-d₄ (Risedronate-d₄) is the deuterium labeled Risedronic acid (HY-B0148). Risedronic acid (Risedronate) is a bisphosphonate and potent antiresorptive agent. Risedronic acid induces Apoptosis. Risedronic acid inhibits the transfer of farnesyl pyrophosphate groups to parasite proteins. Risedronic acid inhibits osteoclast-mediated bone resorption and alters bone metabolism. Risedronic acid inhibits blood-stage Plasmodium falciparum (IC₅₀ of 20.3 μM) .

HY-N12700S

Puberulic acid-13C8
Puberulic acid- ¹³C₈ is the ¹³C-labeled Puberulic acid. Puberulic acid possesses anti-malarial activity with an IC₅₀ value of 0.050 μM against Plasmodium falciparum K1 (chloroquine-resistant) .

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