Pelorol
Pelorol ((-)-Pelorol) is a sesquiterpene found in the tropical marine sponge Dactylospongia elegans. Pelorol has weak antitrypanosomal activity with an IC50 of 17.4 μg/mL and antiplasmodial activity against Plasmodium falciparum clones K1 and NF54 with IC50 values of 786 ng/mL and 1911 ng/mL, respectively. Pelorol is promising for research of parasitic diseases, such as trypanosomiasis and malaria.
For research use only. We do not sell to patients.
- CAS No.: 287974-44-1
- Formula: C23H32O4
- Molecular Weight:372.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Parasite Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 287974-44-1
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Molecular Weight 372.50
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Formula C23H32O4
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SMILES
C[C@]12C3=C(C(OC)=O)C=C(O)C(O)=C3C[C@]1([H])[C@@]4([C@@](C(C)(CCC4)C)([H])CC2)C
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Synonyms
(-)-Pelorol
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Structure Classification
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Initial Source
Dactylospongia elegans
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)