287974-44-1
Chemical Structure
Pelorol
Synonym(s): (-)-Pelorol
- CAS No.: 287974-44-1
- Formula:C23H32O4
- Molecular Weight:372.50
SMILES: C[C@]12C3=C(C(OC)=O)C=C(O)C(O)=C3C[C@]1([H])[C@@]4([C@@](C(C)(CCC4)C)([H])CC2)C
Biological Activity: Pelorol ((-)-Pelorol) is a sesquiterpene found in the tropical marine sponge Dactylospongia elegans. Pelorol has weak antitrypanosomal activity with an IC50 of 17.4 μg/mL and antiplasmodial activity against Plasmodium falciparum clones K1 and NF54 with IC50 values of 786 ng/mL and 1911 ng/mL, respectively. Pelorol is promising for research of parasitic diseases, such as trypanosomiasis and malaria[1].
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Pelorol | Pelorol ((-)-Pelorol) is a sesquiterpene found in the tropical marine sponge Dactylospongia elegans. Pelorol has weak antitrypanosomal activity with an IC50 of 17.4 μg/mL and antiplasmodial activity against Plasmodium falciparum clones K1 and NF54 with IC50 values of 786 ng/mL and 1911 ng/mL, respectively. Pelorol is promising for research of parasitic diseases, such as trypanosomiasis and malaria. | |||||||||||||||||||||
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Keywords
