3,4,5'-Trihydroxy-3'-methoxy-trans-stilbene
3,4,5'-Trihydroxy-3'-methoxy-trans-stilbene (Compound 3) is a stilbenoid compound found in Stuhlmannia moavi. 3,4,5'-Trihydroxy-3'-methoxy-trans-stilbene exerts weak proliferative inhibitory activity and antimalarial activity with IC50 values of 54 and 27 μM against A2780 human ovarian cancer cells and Plasmodium falciparum. 3,4,5'-Trihydroxy-3'-methoxy-trans-stilbene can be used for researches of ovarian cancer and malaria.
For research use only. We do not sell to patients.
- CAS No.: 96853-54-2
- Formula: C15H14O4
- Molecular Weight:258.27
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Parasite Isoforms
More
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
54 μM
Compound: 3
|
Antiproliferative activity against human A2780 cells after 2 days by Alamar Blue assay
Antiproliferative activity against human A2780 cells after 2 days by Alamar Blue assay
|
[PMID: 24239390] |
Chemical Information
-
CAS No. 96853-54-2
-
Molecular Weight 258.27
-
Formula C15H14O4
-
SMILES
OC(C=C1/C=C/C2=CC(OC)=CC(O)=C2)=C(C=C1)O
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)