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Cat. No.: HY-N18179

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8-Acetonyldihydrochelerythrine

8-Acetonylidihydrochelerythrine is a benzophenanthridine alkaloid found in the stem bark of Zanthoxylum gilletii. 8-Acetonylidihydrochelerythrine inhibits growth of Chloroquine (HY-17589A)-resistant and Chloroquine-sensitive Plasmodium falciparum strains. 8-Acetonylidihydrochelerythrine can be used for the research of malaria.

For research use only. We do not sell to patients.

CAS No.: 15575-49-2
Formula: C₂₄H₂₃NO₅
Molecular Weight:405.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

8-Acetonyldihydrochelerythrine Chemical Structure

CAS No.: 15575-49-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
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Biological Activity

Description

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Cellular Effect

Cell Line	Type	Value	Description	References
H9	EC₅₀	1.77 μg/mL Compound: (+/-)-3; (+/-)-ADC	Antiviral activity against HIV infected in human H9 cells Antiviral activity against HIV infected in human H9 cells	[PMID: 27234888]

In Vitro

8-Acetonyldihydrochelerythrine (97.7-50,000 ng/mL; 72 h) exhibits good antiplasmodial activity against Plasmodium falciparum W2, D6, and 3D7 strains, with IC₅₀ values of 9.92 μM, 10.0 μM, and 8.31 μM, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 15575-49-2
Molecular Weight 405.44
Formula C₂₄H₂₃NO₅
SMILES

O=C(CC1C2=C(C3=CC=C4C=C5OCOC5=CC4=C3N1C)C=CC(OC)=C2OC)C
Structure Classification
- Alkaloids
- Quinoline Alkaloids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Omosa LK, Okemwa EK. Antiplasmodial Activities of the Stem bark Extract and Compounds of Zanthoxylum gilletii (De wild) PG Waterman. Pharmacognosy Communications. 2017 Jan 1;7(1).

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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8-Acetonyldihydrochelerythrine

All Parasite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

8-Acetonyldihydrochelerythrine Related Classifications

HY-N18179 Related Classifications