(S)-DSM1465
Based on 1 Customer Validation
(S)-DSM1465 is a Plasmodium dihydroorotate dehydrogenase (DHODH) inhibitor. (S)-DSM1465 exhibits potential inhibitory activity against Plasmodium falciparum and Plasmodium vivax, and can be used in malaria research.
For research use only. We do not sell to patients.
- Purity: 99.53%
- CAS No.: 3109381-05-4
- Formula: C17H12ClF6N5O2
- Molecular Weight:467.75
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 3109381-05-4
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Appearance Solid
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Molecular Weight 467.75
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Formula C17H12ClF6N5O2
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Color White to off-white
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SMILES
O=C1C2=NN(C)C([C@@](O)(C3=CC(Cl)=C(C(F)(F)F)N=C3)C(F)(F)F)=C2N=CN1C4CC4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (213.79 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1379 mL | 10.6895 mL | 21.3789 mL | 53.4474 mL |
| 5 mM | 0.4276 mL | 2.1379 mL | 4.2758 mL | 10.6895 mL | |
| 10 mM | 0.2138 mL | 1.0689 mL | 2.1379 mL | 5.3447 mL | |
| 15 mM | 0.1425 mL | 0.7126 mL | 1.4253 mL | 3.5632 mL | |
| 20 mM | 0.1069 mL | 0.5345 mL | 1.0689 mL | 2.6724 mL | |
| 25 mM | 0.0855 mL | 0.4276 mL | 0.8552 mL | 2.1379 mL | |
| 30 mM | 0.0713 mL | 0.3563 mL | 0.7126 mL | 1.7816 mL | |
| 40 mM | 0.0534 mL | 0.2672 mL | 0.5345 mL | 1.3362 mL | |
| 50 mM | 0.0428 mL | 0.2138 mL | 0.4276 mL | 1.0689 mL | |
| 60 mM | 0.0356 mL | 0.1782 mL | 0.3563 mL | 0.8908 mL | |
| 80 mM | 0.0267 mL | 0.1336 mL | 0.2672 mL | 0.6681 mL | |
| 100 mM | 0.0214 mL | 0.1069 mL | 0.2138 mL | 0.5345 mL |