1. Epigenetics
  2. MicroRNA
  3. LIN28 inhibitor LI71

LIN28 inhibitor LI71 

Cat. No.: HY-123905 Purity: 98.10%
Handling Instructions

LIN28 inhibitor LI71 is a potent and cell-permeable LIN28 inhibitor, which abolishes LIN28-mediated oligouridylation with an IC50 of 7 uM. LIN28 inhibitor LI71 directly binds the cold shock domain (CSD) to suppress LIN28’s activity against let-7 in leukemia cells and embryonic stem cells.

For research use only. We do not sell to patients.

LIN28 inhibitor LI71 Chemical Structure

LIN28 inhibitor LI71 Chemical Structure

CAS No. : 1357248-83-9

Size Price Stock Quantity
5 mg USD 420 In-stock
Estimated Time of Arrival: December 31
10 mg USD 700 In-stock
Estimated Time of Arrival: December 31
50 mg USD 2000 In-stock
Estimated Time of Arrival: December 31
100 mg USD 3000 In-stock
Estimated Time of Arrival: December 31
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500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

LIN28 inhibitor LI71 is a potent and cell-permeable LIN28 inhibitor, which abolishes LIN28-mediated oligouridylation with an IC50 of 7 uM. LIN28 inhibitor LI71 directly binds the cold shock domain (CSD) to suppress LIN28’s activity against let-7 in leukemia cells and embryonic stem cells[1].

IC50 & Target

IC50: 7 uM (LIN28)[1]

Molecular Weight

335.40

Formula

C₂₁H₂₁NO₃

CAS No.
SMILES

O=C(O)C1=CC=C([[email protected]@H]2NC3=C(C=CC=C3OCC)[[email protected]@]4([H])[[email protected]]2([H])CC=C4)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
References
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Keywords:

LIN28 inhibitor LI71MicroRNAmiRNAInhibitorinhibitorinhibit

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LIN28 inhibitor LI71
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HY-123905
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