1. Epigenetics
  2. MicroRNA
  3. LIN28 inhibitor LI71

LIN28 inhibitor LI71 

Cat. No.: HY-123905
Handling Instructions

LIN28 inhibitor LI71 is a potent and cell-permeable LIN28 inhibitor, which abolishes LIN28-mediated oligouridylation with an IC50 of 7 uM. LIN28 inhibitor LI71 directly binds the cold shock domain (CSD) to suppress LIN28’s activity against let-7 in leukemia cells and embryonic stem cells.

For research use only. We do not sell to patients.

LIN28 inhibitor LI71 Chemical Structure

LIN28 inhibitor LI71 Chemical Structure

CAS No. : 1357248-83-9

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Description

LIN28 inhibitor LI71 is a potent and cell-permeable LIN28 inhibitor, which abolishes LIN28-mediated oligouridylation with an IC50 of 7 uM. LIN28 inhibitor LI71 directly binds the cold shock domain (CSD) to suppress LIN28’s activity against let-7 in leukemia cells and embryonic stem cells[1].

IC50 & Target

IC50: 7 uM (LIN28)[1]

Molecular Weight

335.40

Formula

C₂₁H₂₁NO₃

CAS No.

1357248-83-9

SMILES

O=C(O)C1=CC=C([[email protected]@H]2NC3=C(C=CC=C3OCC)[[email protected]@]4([H])[[email protected]]2([H])CC=C4)C=C1

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Please store the product under the recommended conditions in the Certificate of Analysis.

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LIN28 inhibitor LI71
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HY-123905
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