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Cat. No.: HY-N8383

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Butyrolactone V

Butyrolactone V is a butanolide compound. Butyrolactone V shows antiplasmodial activity against Plasmodium falciparum K1 with an IC₅₀ of 7.9 µg/ml.

For research use only. We do not sell to patients.

CAS No.: 1151509-01-1
Formula: C₂₄H₂₄O₈
Molecular Weight:440.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Butyrolactone V Chemical Structure

CAS No.: 1151509-01-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Butyrolactone V is a butanolide compound. Butyrolactone V shows antiplasmodial activity against Plasmodium falciparum K1 with an IC₅₀ of 7.9 µg/ml^[1].

IC₅₀ & Target

Plasmodium

All Parasite Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
BEAS-2B	IC₅₀	>20 μM Compound: 8	Antiproliferative activity against human BEAS2B cells after 24 hrs by CCK8 assay Antiproliferative activity against human BEAS2B cells after 24 hrs by CCK8 assay	[PMID: 30392953]
HCC1806	IC₅₀	>20 μM Compound: 8	Antiproliferative activity against human HCC1806 cells after 24 hrs by CCK8 assay Antiproliferative activity against human HCC1806 cells after 24 hrs by CCK8 assay	[PMID: 30392953]
HepG2	IC₅₀	>20 μM Compound: 8	Antiproliferative activity against human HepG2 cells after 24 hrs by CCK8 assay Antiproliferative activity against human HepG2 cells after 24 hrs by CCK8 assay	[PMID: 30392953]
HT-29	IC₅₀	>20 μM Compound: 8	Antiproliferative activity against human HT-29 cells after 24 hrs by CCK8 assay Antiproliferative activity against human HT-29 cells after 24 hrs by CCK8 assay	[PMID: 30392953]
PANC-1	IC₅₀	>20 μM Compound: 8	Antiproliferative activity against human PANC1 cells after 24 hrs by CCK8 assay Antiproliferative activity against human PANC1 cells after 24 hrs by CCK8 assay	[PMID: 30392953]

Chemical Information

CAS No. 1151509-01-1
Molecular Weight 440.44
Formula C₂₄H₂₄O₈
SMILES

O=C([C@](C(C1=CC=C(O)C=C1)=C2O)(CC3=CC=C4C(C[C@H](O)C(C)(C)O4)=C3)OC2=O)OC
Structure Classification
- Phenols
- Monophenols
- Ketones, Aldehydes, Acids
Initial Source
- Microorganisms
Aspergillus terreus BCC 4651
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Haritakun R, et al. Butyrolactones from the fungus Aspergillus terreus BCC 4651. Chem Pharm Bull (Tokyo). 2010;58(11):1545-1548. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Butyrolactone V

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Penicolinate B

Steffimycin B

Aszonapyrone A

Carbazomycin B

Carbazomycin C

Penicolinate A

Cycloguanil-d6 hydrochloride

Telomycin

Pyrocoll

All Parasite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Butyrolactone V

2-epi-Abamectin

2'-C-Methyladenosine

1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PE

Penicolinate B

Steffimycin B

Aszonapyrone A

Carbazomycin B

Carbazomycin C

Penicolinate A

Cycloguanil-d6 hydrochloride

Telomycin

Pyrocoll

All Parasite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Butyrolactone V Related Classifications

HY-N8383 Related Classifications