VF-149
VF-149 is a Ribonucleotide reductase inhibitor. VF-149 significantly inhibits Plasmodium falciparum growth with an IC50 of 6.4 μM. VF-149 has antimalarial and antitumor activities. VF-149 can be used for malarial infections and cancers research.
For research use only. We do not sell to patients.
- CAS No.: 16053-97-7
- Formula: C7H7NO4
- Molecular Weight:169.13
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 16053-97-7
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Molecular Weight 169.13
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Formula C7H7NO4
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SMILES
O=C(C1=C(O)C(O)=CC=C1)NO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Holland KP, et al. Antimalarial activities of polyhydroxyphenyl and hydroxamic acid derivatives. Antimicrob Agents Chemother. 1998 Sep;42(9):2456-8. [Content Brief]
[2]. Elford HL, et al. New ribonucleotide reductase inhibitors with antineoplastic activity. Cancer Res. 1979 Mar;39(3):844-51. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)