Rutarin
Based on 1 Customer Validation
Rutarin is a Coumarin (HY-N0709) derivative with antimalarial and antifungal activities. Rutarin inhibits Plasmodium falciparum with an IC50 of 88 μg/mL. Rutarin also inhibits Coniophora cerebella.
For research use only. We do not sell to patients.
- Purity : 99.84%
- CAS No.: 20320-81-4
- Formula: C20H24O10
- Molecular Weight:424.40
-
Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
All Parasite Isoforms
More
Biological Activity
Description
In Vitro
Rutarin completely inhibited Coniophora cerebella at a concentration of 40 μg/disc[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
-
CAS No. 20320-81-4
-
Appearance Solid
-
Molecular Weight 424.40
-
Formula C20H24O10
-
Color White to off-white
-
SMILES
O=C1C=CC2=CC3=C(C(OC4C(O)C(O)C(O)C(O4)CO)=C2O1)OC(C3)C(O)(C)C
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
-
Data Sheet (273 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
[2]. Lacroix D, et al. Structure and in vitro antiparasitic activity of constituents of Citropsis articulata root bark. J Nat Prod. 2011 Oct 28;74(10):2286-9. [Content Brief]
[3]. Wolters B, et al. Antimicrobial substances in callus cultures of Ruta graveolens. Planta Med. 1981 Oct;43(2):166-74. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)