Cordysinin C/D
Cordysinin C/D (compound 9) is a potential anti-plasmodial compound that can effectively inhibit Plasmodium falciparum 3D7 strain.
For research use only. We do not sell to patients.
- CAS No.: 148683-93-6
- Formula: C13H12N2O
- Molecular Weight:212.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Parasite Isoforms
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Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | GI50 |
>40 μM
Compound: 42
|
Cytotoxicity activity against human A549 cells assessed as growth inhibition at 10 ug/ml after 72 hrs sulforhodamine B assay
Cytotoxicity activity against human A549 cells assessed as growth inhibition at 10 ug/ml after 72 hrs sulforhodamine B assay
|
[PMID: 21316977] |
| DU-145 | GI50 |
>40 μM
Compound: 42
|
Cytotoxicity activity against human DU145 cells assessed as growth inhibition at 10 ug/ml after 72 hrs sulforhodamine B assay
Cytotoxicity activity against human DU145 cells assessed as growth inhibition at 10 ug/ml after 72 hrs sulforhodamine B assay
|
[PMID: 21316977] |
| KB | GI50 |
>40 μM
Compound: 42
|
Cytotoxicity activity against human KB cells assessed as growth inhibition at 10 ug/ml after 72 hrs sulforhodamine B assay
Cytotoxicity activity against human KB cells assessed as growth inhibition at 10 ug/ml after 72 hrs sulforhodamine B assay
|
[PMID: 21316977] |
| Neutrophil | IC50 |
>30 μM
Compound: 42
|
Antiinflammatory activity against human neutrophil assessed as inhibition of N-formyl-l-methionyl phenylalanine/cytochalasin B-induced elastase release
Antiinflammatory activity against human neutrophil assessed as inhibition of N-formyl-l-methionyl phenylalanine/cytochalasin B-induced elastase release
|
[PMID: 21316977] |
| Neutrophil | IC50 |
9.4 μM
Compound: 42
|
Antiinflammatory activity against human neutrophil assessed as inhibition of N-formyl-l-methionyl phenylalanine/cytochalasin B-induced superoxide anion generation by spectrophotometry
Antiinflammatory activity against human neutrophil assessed as inhibition of N-formyl-l-methionyl phenylalanine/cytochalasin B-induced superoxide anion generation by spectrophotometry
|
[PMID: 21316977] |
Chemical Information
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CAS No. 148683-93-6
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Molecular Weight 212.25
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Formula C13H12N2O
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SMILES
OC(C)C1=NC=CC2=C1NC3=C2C=CC=C3
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Structure Classification
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Initial Source
Orthoscuticella ventricosa
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)