MMV1634566
MMV1634566 is a potent antimalarial agent. MMV1634566 inhibits Plasmodium falciparum. MMV1634566 shows cytotoxicity.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C22H25N5O2
- Molecular Weight:391.47
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | CC50 |
4.81 μM
Compound: 5w; MMV1634566
|
Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth incubated for 48 hrs by CellTiter-Glo luminescence assay
Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth incubated for 48 hrs by CellTiter-Glo luminescence assay
|
[PMID: 39024967] |
In Vitro
MMV1634566 (0-40 µM; 48 h) inhibits cell growth with a CC50 value of 4.81 µM for HepG2 cells[1].
MMV1634566 (72 h) inhibits Plasmodium falciparum 3D7 parasites with EC50 value of 0.016 µM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 391.47
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Formel C22H25N5O2
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SMILES
O=C(C1=C2C(N(C(C)(C)C)N=C2C)=NC(C3CC3)=C1)N4C(C=NC=C5)=C5OCC4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)