trans-Clopenthixol dihydrochloride
Based on 1 Customer Validation
trans-Clopenthixol ((E)-Clopenthixol) dihydrochloride is an antibiotic agent, without neuroleptic effect. trans-Clopenthixol dihydrochloride can be used to inhibit Pseudomonas aeruginosa and Plasmodium falciparum in vitro.
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- Purity : 99.98%
- CAS No.: 58045-22-0
- 화학식: C22H27Cl3N2OS
- 분자량:473.89
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보관:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
Chemical Information
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CAS No. 58045-22-0
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Appearance Solid
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분자량 473.89
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화학식 C22H27Cl3N2OS
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Color Off-white to light yellow
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SMILES
OCCN(CC1)CCN1CC/C=C2C3=CC(Cl)=CC=C3SC4=CC=CC=C4/2.[H]Cl.[H]Cl
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Synonyms
(E)-Clopenthixol dihydrochloride
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
용액&용해도
In Vitro:
DMSO : 10 mg/mL (21.10 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
순도&문서
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Kristiansen JE, et al. The susceptibility of Plasmodium falciparum in vitro to chlorpromazine and the stereo-isomeric compounds cis(Z)- and trans(E)-clopenthixol. Acta Pathol Microbiol Immunol Scand B. 1985 Jun;93(3):249-51. [Content Brief]
[2]. Kristiansen JE, et al. Stereo-isomeric dissociation of the antibacterial and the neuroleptic effect of clopenthixol. Acta Pathol Microbiol Scand B. 1981 Dec;89(6):437-8. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1102 mL | 10.5510 mL | 21.1019 mL | 52.7549 mL |
| 5 mM | 0.4220 mL | 2.1102 mL | 4.2204 mL | 10.5510 mL | |
| 10 mM | 0.2110 mL | 1.0551 mL | 2.1102 mL | 5.2755 mL | |
| 15 mM | 0.1407 mL | 0.7034 mL | 1.4068 mL | 3.5170 mL | |
| 20 mM | 0.1055 mL | 0.5275 mL | 1.0551 mL | 2.6377 mL |
trans-Clopenthixol dihydrochloride Related Classifications
HY-A0163C Related Classifications
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