PfCLK3-IN-1
PfCLK3-IN-1 (Compound 4) is a covalent inhibitor for Plasmodium falciparum CLK3 (Pf CLK3) under alkaline conditions with an pEC50 of 7.1. PfCLK3-IN-1 reduces mature gametocytes in sexual stage parasites, and prevents transmission. PfCLK3-IN-1 inhibits P. falciparum Dd2-B2 clone with an IC50 of 239.5 nM.
For research use only. We do not sell to patients.
- Formula: C28H27ClN4O4
- Molecular Weight:518.99
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Parasite Isoforms
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Biological Activity
Chemical Information
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Molecular Weight 518.99
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Formula C28H27ClN4O4
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SMILES
O=C(O)C1=CC=C(C2=C3C(NC(C4=CC(CN5CCN(C(CCl)=O)CC5)=CC=C4OC)=C3)=NC=C2)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)