2. Metabolic Enzyme/Protease
  3. Farnesyl Transferase
  4. FTI 276

FTI-276 is a protein farnesyl transferase (PFT) inhibitor with IC50s of 0.9 and 0.5 nM for Plasmodium falciparum and human.

The free form of the compound is prone to instability, it is advisable to consider the stable salt form (FTI 276 TFA) that retains the same biological activity.

For research use only. We do not sell to patients.

FTI 276 Chemical Structure

FTI 276 Chemical Structure

CAS No. : 170006-72-1

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Other Forms of FTI 276:

FTI 276 Related Antibodies

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Description

FTI-276 is a protein farnesyl transferase (PFT) inhibitor with IC50s of 0.9 and 0.5 nM for Plasmodium falciparum and human.

IC50 & Target

IC50: 0.9 and 0.5 nM for Plasmodium falciparum and human[1].
Molecular Weight

433.59

Formula

C21H27N3O3S2
CAS No.
SMILES

O=C(O)[C@@H](NC(C1=CC=C(NC[C@@H](N)CS)C=C1C2=CC=CC=C2)=O)CCSC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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FTI 276 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FTI 276170006-72-1FTI276FTI-276Farnesyl TransferaseFtaseInhibitorinhibitorinhibit

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