Mollicellin K
Mollicellin K is a depsidone that can be isolated from the fungus Chaetomium brasiliense. Mollicellin K exhibits antimicrobial activity against Myobacterium tuberculosis, antimalarial activity (IC50 = 1.2 μM) against Plasmodium falciparum as well as antifungal property (IC50 = 1.2 μM) against Candida albicans. Mollicellin K is cytotoxic against KB (IC50 = 1.9 μM), BC1 (IC50 = 6.8 μM), NCI-H187 (IC50 = 0.35 μM), and five cholangiocarcinoma cell lines. Mollicellin K also has an MIC of 12.5 μM for tuberculosis.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 1179374-63-0
- Formel: C21H18O7
- Molecular Weight:382.36
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Alle Parasite Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
Beschreibung
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| KB | IC50 |
1.9 μg/mL
Compound: 1
|
Cytotoxicity against human KB cells by SRB assay
Cytotoxicity against human KB cells by SRB assay
|
[PMID: 19663417] |
Chemical Information
-
CAS. Nr. 1179374-63-0
-
Molecular Weight 382.36
-
Formel C21H18O7
-
SMILES
O=CC1=C(C=C(C)C(C(OC2=C3C)=O)=C1OC2=CC(O)=C3C(/C=C(C)\C)=O)O
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)