1. Anti-infection
  2. Fungal Bacterial Parasite
  3. Mollicellin K

Mollicellin K is a depsidone that can be isolated from the fungus Chaetomium brasiliense. Mollicellin K exhibits antimicrobial activity against Myobacterium tuberculosis, antimalarial activity (IC50 = 1.2 μM) against Plasmodium falciparum as well as antifungal property (IC50 = 1.2 μM) against Candida albicans. Mollicellin K is cytotoxic against KB (IC50 = 1.9 μM), BC1 (IC50 = 6.8 μM), NCI-H187 (IC50 = 0.35 μM), and five cholangiocarcinoma cell lines. Mollicellin K also has an MIC of 12.5 μM for tuberculosis.

For research use only. We do not sell to patients.

Mollicellin K

Mollicellin K Chemical Structure

CAS No. : 1179374-63-0

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Description

Mollicellin K is a depsidone that can be isolated from the fungus Chaetomium brasiliense. Mollicellin K exhibits antimicrobial activity against Myobacterium tuberculosis, antimalarial activity (IC50 = 1.2 μM) against Plasmodium falciparum as well as antifungal property (IC50 = 1.2 μM) against Candida albicans. Mollicellin K is cytotoxic against KB (IC50 = 1.9 μM), BC1 (IC50 = 6.8 μM), NCI-H187 (IC50 = 0.35 μM), and five cholangiocarcinoma cell lines. Mollicellin K also has an MIC of 12.5 μM for tuberculosis[1].

Molecular Weight

382.36

Formula

C21H18O7

CAS No.
SMILES

O=CC1=C(C=C(C)C(C(OC2=C3C)=O)=C1OC2=CC(O)=C3C(/C=C(C)\C)=O)O

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Mollicellin K
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HY-178724
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