Sulfalene (Standard)
Sulfalene (Standard) is the analytical standard of Sulfalene. This product is intended for research and analytical applications. Sulfalene (Sulfametopyrazine; AS-18908) is an orally active antimalarial agent. Sulfalene competes for para-aminobenzoic acid binding in plasmodial folic acid synthesis. Sulfalene, combined with Trimethoprim (HY-B0510), clears parasites, resolves fever, and resists induced resistance against drug-sensitive and drug-resistant Plasmodium falciparum. Sulfalene can be used for the research of acute falciparum malaria and Schistosoma mansoni infection.
For research use only. We do not sell to patients.
- CAS No.: 152-47-6
- Formula: C11H12N4O3S
- Molecular Weight:280.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 152-47-6
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Molecular Weight 280.30
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Formula C11H12N4O3S
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SMILES
O=S(C1=CC=C(N)C=C1)(NC2=NC=CN=C2OC)=O
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Synonyms
Sulfametopyrazine (Standard); AS-18908 (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Martin DC, et al. Treatment of acute falciparum malaria with sulfalene and trimethoprim. JAMA. 1968 Feb 12;203(7):476-80. [Content Brief]
[2]. Obonyo CO, et al. Efficacy of artesunate with sulfalene plus pyrimethamine versus praziquantel for treatment of Schistosoma mansoni in Kenyan children: an open-label randomised controlled trial. Lancet Infect Dis. 2010;10(9):603-611. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)