Tebuquine
Tebuquine (WR228258), a 4-aminoquinoline, is a potent antimalarial agent. Tebuquine is active against the Chloroquine (HY-17589A) sensitive HB3 strain and the Chloroquine resistant K1 strain of Plasmodium falciparum with IC50s of 0.9 nM and 20.8 nM, respectively.
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- CAS No.: 74129-03-6
- Formule: C26H25Cl2N3O
- Masse moléculaire:466.40
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| J774 | IC50 |
1.8 μg/mL
Compound: tebuquine
|
Toxicity against murine J774 macrophage cells
Toxicity against murine J774 macrophage cells
|
[PMID: 17266295] |
Chemical Information
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CAS No. 74129-03-6
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Masse moléculaire 466.40
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Formule C26H25Cl2N3O
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SMILES
ClC1=CC=C(C2=CC(NC3=C4C=CC(Cl)=CC4=NC=C3)=CC(CNC(C)(C)C)=C2O)C=C1
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Synonyms
WR228258
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)