1. Metabolic Enzyme/Protease
  2. Drug Metabolite
  3. Didesethyl chloroquine

Didesethyl chloroquine  (Synonyms: Bisdesethylchloroquine)

Cat. No.: HY-100662 Purity: 99.91%
COA Handling Instructions

Didesethyl chloroquine (Bisdesethylchloroquine) is a major metabolite of the antimalarial agent Chloroquine. Didesethyl chloroquine is a potent myocardial depressant.

For research use only. We do not sell to patients.

Didesethyl chloroquine Chemical Structure

Didesethyl chloroquine Chemical Structure

CAS No. : 4298-14-0

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
USD 605 In-stock
Solution
10 mM * 1 mL in DMSO USD 605 In-stock
Solid
5 mg USD 550 In-stock
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50 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of Didesethyl chloroquine:

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Description

Didesethyl chloroquine (Bisdesethylchloroquine) is a major metabolite of the antimalarial agent Chloroquine. Didesethyl chloroquine is a potent myocardial depressant[1][2].

Molecular Weight

263.77

Formula

C14H18ClN3

CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

CC(NC1=CC=NC2=CC(Cl)=CC=C12)CCCN

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (379.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7912 mL 18.9559 mL 37.9118 mL
5 mM 0.7582 mL 3.7912 mL 7.5824 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.7912 mL 18.9559 mL 37.9118 mL 94.7795 mL
5 mM 0.7582 mL 3.7912 mL 7.5824 mL 18.9559 mL
10 mM 0.3791 mL 1.8956 mL 3.7912 mL 9.4780 mL
15 mM 0.2527 mL 1.2637 mL 2.5275 mL 6.3186 mL
20 mM 0.1896 mL 0.9478 mL 1.8956 mL 4.7390 mL
25 mM 0.1516 mL 0.7582 mL 1.5165 mL 3.7912 mL
30 mM 0.1264 mL 0.6319 mL 1.2637 mL 3.1593 mL
40 mM 0.0948 mL 0.4739 mL 0.9478 mL 2.3695 mL
50 mM 0.0758 mL 0.3791 mL 0.7582 mL 1.8956 mL
60 mM 0.0632 mL 0.3159 mL 0.6319 mL 1.5797 mL
80 mM 0.0474 mL 0.2369 mL 0.4739 mL 1.1847 mL
100 mM 0.0379 mL 0.1896 mL 0.3791 mL 0.9478 mL
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Didesethyl chloroquine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Didesethyl chloroquine
Cat. No.:
HY-100662
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